Compounds in cluster

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3 similar compounds to monomer 50163999

Wt: 407.9
BDBM28961

Wt: 417.5
BDBM50163998

Wt: 387.4
BDBM50164001

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 28961,50163998,50164001
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-Secretase (Homo sapiens (human)-Homo sapiens (Human))	BDBM28961 (CHEMBL180641 \| ethyl 4-[(4-chlorobenzene)sulfonyl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...				Bioorg Med Chem Lett 18: 4232-6 (2008)
Wyeth Research					More data for this Ligand-Target Pair
Beta amyloid A4 protein (Homo sapiens (human))	BDBM28961 (CHEMBL180641 \| ethyl 4-[(4-chlorobenzene)sulfonyl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro effective concentration against beta amyloid protein 42 in ELISA				Bioorg Med Chem Lett 15: 1891-4 (2005)
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Beta amyloid A4 protein (Homo sapiens (human))	BDBM50164001 (4-Benzenesulfonyl-4-o-tolyl-piperidine-1-carboxyli...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro effective concentration against beta amyloid protein 40 in ELISA				Bioorg Med Chem Lett 15: 1891-4 (2005)
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Beta amyloid A4 protein (Homo sapiens (human))	BDBM28961 (CHEMBL180641 \| ethyl 4-[(4-chlorobenzene)sulfonyl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro effective concentration against beta amyloid protein 40 in ELISA				Bioorg Med Chem Lett 15: 1891-4 (2005)
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Beta amyloid A4 protein (Homo sapiens (human))	BDBM50163998 (4-(4-Methoxy-benzenesulfonyl)-4-o-tolyl-piperidine...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro effective concentration against beta amyloid protein 40 in ELISA				Bioorg Med Chem Lett 15: 1891-4 (2005)
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair