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53 similar compounds to monomer 50217172

Compile data set for download or QSAR
Wt: 509.4
BDBM29012
Wt: 421.4
BDBM50227352
Wt: 285.3
BDBM50217151
Wt: 485.6
BDBM50217143
Wt: 246.3
BDBM50217144
Wt: 442.5
BDBM50217145
Wt: 456.6
BDBM50217140
Wt: 462.6
BDBM50217138
Wt: 429.5
BDBM50217141
Wt: 472.6
BDBM50217142
Wt: 498.7
BDBM50217147
Wt: 471.6
BDBM50217148
Wt: 469.9
BDBM50217152
Wt: 574.6
BDBM50217165
Wt: 533.5
BDBM50217166
Displayed 1 to 15 (of 53 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 29012,50227352,50217151,50217143,50217144,50217145,50217140,50217138,50217141,50217142,50217147,50217148,50217152,50217165,50217166   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217138
PNG
(CHEMBL90433)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(N)sc2C1
Show InChI InChI=1S/C27H34N4OS/c1-2-17-31(23-14-15-24-25(19-23)33-27(28)30-24)18-7-6-16-29-26(32)22-12-10-21(11-13-22)20-8-4-3-5-9-20/h3-5,8-13,23H,2,6-7,14-19H2,1H3,(H2,28,30)(H,29,32)
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0.501n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217144
PNG
(CHEMBL91433)
Show SMILES CCCN1CCC[C@H]2Cc3nc(N)ncc3C[C@H]12
Show InChI InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m0/s1
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1n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217165
PNG
(CHEMBL367129)
Show SMILES CC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1
Show InChI InChI=1S/C29H29F3N2O5S/c1-20(35)21-4-6-22(7-5-21)23-8-10-25(11-9-23)28(36)33-15-2-3-16-34-17-14-24-12-13-27(18-26(24)19-34)39-40(37,38)29(30,31)32/h4-13,18H,2-3,14-17,19H2,1H3,(H,33,36)
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2.5n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells


Bioorg Med Chem Lett 9: 179-84 (1999)


Article DOI: 10.1016/s0960-894x(98)00699-4
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217142
PNG
(CHEMBL93794)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2ncnc(OC)c2C1
Show InChI InChI=1S/C29H36N4O2/c1-3-18-33(25-15-16-27-26(20-25)29(35-2)32-21-31-27)19-8-7-17-30-28(34)24-13-11-23(12-14-24)22-9-5-4-6-10-22/h4-6,9-14,21,25H,3,7-8,15-20H2,1-2H3,(H,30,34)
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3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217166
PNG
(CHEMBL52901)
Show SMILES FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3cnc4ccccc4c3)Cc2c1
Show InChI InChI=1S/C26H26F3N3O4S/c27-26(28,29)37(34,35)36-23-9-8-20-11-14-32(18-22(20)16-23)13-4-3-12-30-25(33)10-7-19-15-21-5-1-2-6-24(21)31-17-19/h1-2,5-10,15-17H,3-4,11-14,18H2,(H,30,33)/b10-7+
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4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells


Bioorg Med Chem Lett 9: 179-84 (1999)


Article DOI: 10.1016/s0960-894x(98)00699-4
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217140
PNG
(CHEMBL93336)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(C)ncc2C1
Show InChI InChI=1S/C29H36N4O/c1-3-18-33(27-15-16-28-26(20-27)21-31-22(2)32-28)19-8-7-17-30-29(34)25-13-11-24(12-14-25)23-9-5-4-6-10-23/h4-6,9-14,21,27H,3,7-8,15-20H2,1-2H3,(H,30,34)
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7.90n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217141
PNG
(CHEMBL93703)
Show SMILES CN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(N)ncc2C1
Show InChI InChI=1S/C26H31N5O/c1-31(23-13-14-24-22(17-23)18-29-26(27)30-24)16-6-5-15-28-25(32)21-11-9-20(10-12-21)19-7-3-2-4-8-19/h2-4,7-12,18,23H,5-6,13-17H2,1H3,(H,28,32)(H2,27,29,30)
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10n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217147
PNG
(CHEMBL92439)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(ncc2C1)C(C)(C)C
Show InChI InChI=1S/C32H42N4O/c1-5-20-36(28-17-18-29-27(22-28)23-34-31(35-29)32(2,3)4)21-10-9-19-33-30(37)26-15-13-25(14-16-26)24-11-7-6-8-12-24/h6-8,11-16,23,28H,5,9-10,17-22H2,1-4H3,(H,33,37)
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13n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217148
PNG
(CHEMBL91510)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(NC)ncc2C1
Show InChI InChI=1S/C29H37N5O/c1-3-18-34(26-15-16-27-25(20-26)21-32-29(30-2)33-27)19-8-7-17-31-28(35)24-13-11-23(12-14-24)22-9-5-4-6-10-22/h4-6,9-14,21,26H,3,7-8,15-20H2,1-2H3,(H,31,35)(H,30,32,33)
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16n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217143
PNG
(CHEMBL90897)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(ncc2C1)N(C)C
Show InChI InChI=1S/C30H39N5O/c1-4-19-35(27-16-17-28-26(21-27)22-32-30(33-28)34(2)3)20-9-8-18-31-29(36)25-14-12-24(13-15-25)23-10-6-5-7-11-23/h5-7,10-15,22,27H,4,8-9,16-21H2,1-3H3,(H,31,36)
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25n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50217145
PNG
(CHEMBL92438)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2ncncc2C1
Show InChI InChI=1S/C28H34N4O/c1-2-17-32(26-14-15-27-25(19-26)20-29-21-31-27)18-7-6-16-30-28(33)24-12-10-23(11-13-24)22-8-4-3-5-9-22/h3-5,8-13,20-21,26H,2,6-7,14-19H2,1H3,(H,30,33)
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126n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50227352
PNG
(CHEMBL300906)
Show SMILES COc1cc(ccc1Cc1nn(C)c2ccc(NC(=O)CC3CCCC3)cc12)C(O)=O
Show InChI InChI=1S/C24H27N3O4/c1-27-21-10-9-18(25-23(28)11-15-5-3-4-6-15)14-19(21)20(26-27)12-16-7-8-17(24(29)30)13-22(16)31-2/h7-10,13-15H,3-6,11-12H2,1-2H3,(H,25,28)(H,29,30)
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132n/an/an/an/an/an/an/an/a



ICI Pharmaceuticals Group

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]LTD4 on guinea pig lung parenchymal membranes.


J Med Chem 33: 1781-90 (1990)


Article DOI: 10.1021/jm00168a037
BindingDB Entry DOI: 10.7270/Q2862FDP
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217138
PNG
(CHEMBL90433)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(N)sc2C1
Show InChI InChI=1S/C27H34N4OS/c1-2-17-31(23-14-15-24-25(19-23)33-27(28)30-24)18-7-6-16-29-26(32)22-12-10-21(11-13-22)20-8-4-3-5-9-20/h3-5,8-13,23H,2,6-7,14-19H2,1H3,(H2,28,30)(H,29,32)
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200n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217165
PNG
(CHEMBL367129)
Show SMILES CC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1
Show InChI InChI=1S/C29H29F3N2O5S/c1-20(35)21-4-6-22(7-5-21)23-8-10-25(11-9-23)28(36)33-15-2-3-16-34-17-14-24-12-13-27(18-26(24)19-34)39-40(37,38)29(30,31)32/h4-13,18H,2-3,14-17,19H2,1H3,(H,33,36)
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200n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 179-84 (1999)


Article DOI: 10.1016/s0960-894x(98)00699-4
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217166
PNG
(CHEMBL52901)
Show SMILES FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3cnc4ccccc4c3)Cc2c1
Show InChI InChI=1S/C26H26F3N3O4S/c27-26(28,29)37(34,35)36-23-9-8-20-11-14-32(18-22(20)16-23)13-4-3-12-30-25(33)10-7-19-15-21-5-1-2-6-24(21)31-17-19/h1-2,5-10,15-17H,3-4,11-14,18H2,(H,30,33)/b10-7+
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316n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 179-84 (1999)


Article DOI: 10.1016/s0960-894x(98)00699-4
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217145
PNG
(CHEMBL92438)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2ncncc2C1
Show InChI InChI=1S/C28H34N4O/c1-2-17-32(26-14-15-27-25(19-26)20-29-21-31-27)18-7-6-16-30-28(33)24-12-10-23(11-13-24)22-8-4-3-5-9-22/h3-5,8-13,20-21,26H,2,6-7,14-19H2,1H3,(H,30,33)
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1.26E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217143
PNG
(CHEMBL90897)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(ncc2C1)N(C)C
Show InChI InChI=1S/C30H39N5O/c1-4-19-35(27-16-17-28-26(21-27)22-32-30(33-28)34(2)3)20-9-8-18-31-29(36)25-14-12-24(13-15-25)23-10-6-5-7-11-23/h5-7,10-15,22,27H,4,8-9,16-21H2,1-3H3,(H,31,36)
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1.59E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217141
PNG
(CHEMBL93703)
Show SMILES CN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(N)ncc2C1
Show InChI InChI=1S/C26H31N5O/c1-31(23-13-14-24-22(17-23)18-29-26(27)30-24)16-6-5-15-28-25(32)21-11-9-20(10-12-21)19-7-3-2-4-8-19/h2-4,7-12,18,23H,5-6,13-17H2,1H3,(H,28,32)(H2,27,29,30)
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1.59E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217142
PNG
(CHEMBL93794)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2ncnc(OC)c2C1
Show InChI InChI=1S/C29H36N4O2/c1-3-18-33(25-15-16-27-26(20-25)29(35-2)32-21-31-27)19-8-7-17-30-28(34)24-13-11-23(12-14-24)22-9-5-4-6-10-22/h4-6,9-14,21,25H,3,7-8,15-20H2,1-2H3,(H,30,34)
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1.59E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217147
PNG
(CHEMBL92439)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(ncc2C1)C(C)(C)C
Show InChI InChI=1S/C32H42N4O/c1-5-20-36(28-17-18-29-27(22-28)23-34-31(35-29)32(2,3)4)21-10-9-19-33-30(37)26-15-13-25(14-16-26)24-11-7-6-8-12-24/h6-8,11-16,23,28H,5,9-10,17-22H2,1-4H3,(H,33,37)
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1.59E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217148
PNG
(CHEMBL91510)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(NC)ncc2C1
Show InChI InChI=1S/C29H37N5O/c1-3-18-34(26-15-16-27-25(20-26)21-32-29(30-2)33-27)19-8-7-17-31-28(35)24-13-11-23(12-14-24)22-9-5-4-6-10-22/h4-6,9-14,21,26H,3,7-8,15-20H2,1-2H3,(H,31,35)(H,30,32,33)
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2.51E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50217140
PNG
(CHEMBL93336)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2nc(C)ncc2C1
Show InChI InChI=1S/C29H36N4O/c1-3-18-33(27-15-16-28-26(20-27)21-31-22(2)32-28)19-8-7-17-30-29(34)25-13-11-24(12-14-25)23-9-5-4-6-10-23/h4-6,9-14,21,27H,3,7-8,15-20H2,1-2H3,(H,30,34)
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2.51E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [125I]iodosulpiride from human Dopamine receptor D2 expressed in CHO cells


Bioorg Med Chem Lett 9: 2715-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00454-0
More data for this
Ligand-Target Pair
Gamma-Secretase


(Homo sapiens (Human))
BDBM29012
PNG
(N-[(4R)-4-{[5-chloro-2-(hydroxymethyl)phenyl](4-ch...)
Show SMILES C[C@H](CCCN(C)S(C)(=O)=O)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H26Cl2N2O5S2/c1-15(5-4-12-23(2)30(3,26)27)24(20-13-18(22)7-6-16(20)14-25)31(28,29)19-10-8-17(21)9-11-19/h6-11,13,15,25H,4-5,12,14H2,1-3H3/t15-/m1/s1
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n/an/an/an/a 0.320n/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...


Bioorg Med Chem Lett 18: 464-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.102
BindingDB Entry DOI: 10.7270/Q2Z60MD6
More data for this
Ligand-Target Pair
Sodium channel protein type I I alpha subunit


(Rattus norvegicus)
BDBM50217151
PNG
(CHEMBL419673)
Show SMILES C[C@H](NCc1ccc(OCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C17H19NO3/c1-13(17(19)20)18-11-14-7-9-16(10-8-14)21-12-15-5-3-2-4-6-15/h2-10,13,18H,11-12H2,1H3,(H,19,20)/t13-/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Pharmacia& Upjohn

Curated by ChEMBL


Assay Description
Inhibition of [3H]saxitoxin binding to rat brain sodium channel


Bioorg Med Chem Lett 9: 2521-4 (1999)


Article DOI: 10.1016/s0960-894x(99)00415-1
BindingDB Entry DOI: 10.7270/Q29887HT
More data for this
Ligand-Target Pair
Sodium channel protein type I I alpha subunit


(Rattus norvegicus)
BDBM50217151
PNG
(CHEMBL419673)
Show SMILES C[C@H](NCc1ccc(OCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C17H19NO3/c1-13(17(19)20)18-11-14-7-9-16(10-8-14)21-12-15-5-3-2-4-6-15/h2-10,13,18H,11-12H2,1H3,(H,19,20)/t13-/m0/s1
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n/an/a 1.51E+5n/an/an/an/an/an/a



Pharmacia& Upjohn

Curated by ChEMBL


Assay Description
Inhibition of [3H]batrachotoxin binding to rat brain sodium channel


Bioorg Med Chem Lett 9: 2521-4 (1999)


Article DOI: 10.1016/s0960-894x(99)00415-1
BindingDB Entry DOI: 10.7270/Q29887HT
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50217152
PNG
(CHEMBL314963)
Show SMILES CN1CCCC[C@H]1CCOc1c(c(O)nc2cc(Cl)c(cc12)[N+]([O-])=O)-c1cc(C)cc(C)c1
Show InChI InChI=1S/C25H28ClN3O4/c1-15-10-16(2)12-17(11-15)23-24(33-9-7-18-6-4-5-8-28(18)3)19-13-22(29(31)32)20(26)14-21(19)27-25(23)30/h10-14,18H,4-9H2,1-3H3,(H,27,30)/t18-/m0/s1
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n/an/a 20n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for Gonadotropin-releasing hormone receptor in rat pituitary membrane at 10 buserelin as radioligand


Bioorg Med Chem Lett 9: 2621-4 (1999)


Article DOI: 10.1016/s0960-894x(99)00447-3
BindingDB Entry DOI: 10.7270/Q2PN94VN
More data for this
Ligand-Target Pair