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2 similar compounds to monomer 35099

Wt: 437.9
BDBM35092
Wt: 375.8
BDBM35098

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35092,35098   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Liver X Receptor beta (LXR-beta)


(Homo sapiens (human))
BDBM35092
PNG
(biarylether alcohol quinoline, 5e)
Show SMILES OCc1ccc(Oc2cccc(c2)-c2c(cnc3c(Cl)cccc23)-c2ccccc2)cc1
Show InChI InChI=1S/C28H20ClNO2/c29-26-11-5-10-24-27(25(17-30-28(24)26)20-6-2-1-3-7-20)21-8-4-9-23(16-21)32-22-14-12-19(18-31)13-15-22/h1-17,31H,18H2
PDB
MMDB

KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.30n/a 1.01E+3n/an/a7.44



Wyeth Research



Assay Description
Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...


Citation and Details
More data for this
Ligand-Target Pair
Liver X Receptor alpha (LXR-alpha)


(Homo sapiens (human))
BDBM35098
PNG
(biarylether alcohol quinoline, 5h)
Show SMILES Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(CO)c2)c1
Show InChI InChI=1S/C23H18ClNO2/c1-15-13-25-23-20(9-4-10-21(23)24)22(15)17-6-3-8-19(12-17)27-18-7-2-5-16(11-18)14-26/h2-13,26H,14H2,1H3
PDB
MMDB

Reactome pathway

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 59n/an/an/an/a7.44



Wyeth Research



Assay Description
Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRalpha coated flash plates. Each concentration of...


Citation and Details
More data for this
Ligand-Target Pair
Liver X Receptor alpha (LXR-alpha)


(Homo sapiens (human))
BDBM35092
PNG
(biarylether alcohol quinoline, 5e)
Show SMILES OCc1ccc(Oc2cccc(c2)-c2c(cnc3c(Cl)cccc23)-c2ccccc2)cc1
Show InChI InChI=1S/C28H20ClNO2/c29-26-11-5-10-24-27(25(17-30-28(24)26)20-6-2-1-3-7-20)21-8-4-9-23(16-21)32-22-14-12-19(18-31)13-15-22/h1-17,31H,18H2
PDB
MMDB

Reactome pathway

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 36n/an/an/an/a7.44



Wyeth Research



Assay Description
Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRalpha coated flash plates. Each concentration of...


Citation and Details
More data for this
Ligand-Target Pair
Liver X Receptor beta (LXR-beta)


(Homo sapiens (human))
BDBM35098
PNG
(biarylether alcohol quinoline, 5h)
Show SMILES Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(CO)c2)c1
Show InChI InChI=1S/C23H18ClNO2/c1-15-13-25-23-20(9-4-10-21(23)24)22(15)17-6-3-8-19(12-17)27-18-7-2-5-16(11-18)14-26/h2-13,26H,14H2,1H3
PDB
MMDB

KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/a 938n/an/a7.44



Wyeth Research



Assay Description
Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...


Citation and Details
More data for this
Ligand-Target Pair