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2 similar compounds to monomer 3588

Compile data set for download or QSAR
Wt: 355.8
BDBM3591
Wt: 239.2
BDBM3629

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3591,3629   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM3629
PNG
(US8524699, 46)
Show SMILES O=c1c(c[nH]n1-c1cnccn1)-c1cccnc1
Show InChI InChI=1S/C12H9N5O/c18-12-10(9-2-1-3-13-6-9)7-16-17(12)11-8-14-4-5-15-11/h1-8,16H
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 930n/an/an/an/a7.525



Bayer Intellectual Property GmbH

US Patent


Assay Description
In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.


US Patent US8524699 (2013)


BindingDB Entry DOI: 10.7270/Q2TB15J4
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM3591
PNG
(US8524699, 7)
Show SMILES Clc1ccc(cc1)-c1nnc(s1)-n1[nH]cc(-c2cccnc2)c1=O
Show InChI InChI=1S/C16H10ClN5OS/c17-12-5-3-10(4-6-12)14-20-21-16(24-14)22-15(23)13(9-19-22)11-2-1-7-18-8-11/h1-9,19H
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 880n/an/an/an/a7.525



Bayer Intellectual Property GmbH

US Patent


Assay Description
In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.


US Patent US8524699 (2013)


BindingDB Entry DOI: 10.7270/Q2TB15J4
More data for this
Ligand-Target Pair