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24 similar compounds to monomer 50044849

Wt: 302.3
BDBM41345
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Wt: 331.3
BDBM71814
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Wt: 307.3
BDBM50441973
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Wt: 291.3
BDBM50441976
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Wt: 277.3
BDBM50441977
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Wt: 319.4
BDBM50044904
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Wt: 319.4
BDBM50044909
Wt: 347.4
BDBM50044918
Wt: 345.4
BDBM50044919
Wt: 291.3
BDBM50044851
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Wt: 291.3
BDBM50044853
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Wt: 359.3
BDBM50044856
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Wt: 309.3
BDBM50044858
Wt: 321.3
BDBM50044870
Wt: 331.4
BDBM50044873
Displayed 1 to 15 (of 24 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 41345,71814,50441973,50441976,50441977,50044904,50044909,50044918,50044919,50044851,50044853,50044856,50044858,50044870,50044873   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytohesin-2


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
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1.61E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cytohesin-2


(Homo sapiens)
BDBM50441976
PNG
(CHEMBL2440213)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO3S/c1-10-4-6-14(7-5-10)20(18,19)16-15-11(2)8-13(17)9-12(15)3/h4-9,16-17H,1-3H3
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1.91E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
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3.72E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hsf1 protein


(Mus musculus)
BDBM71814
PNG
(4-methoxy-N-[2-(trifluoromethyl)phenyl]benzenesulf...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(F)(F)F
Show InChI InChI=1S/C14H12F3NO3S/c1-21-10-6-8-11(9-7-10)22(19,20)18-13-5-3-2-4-12(13)14(15,16)17/h2-9,18H,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
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n/an/an/a 5.00E+5n/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044851
PNG
(CHEMBL3311306)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cccc1C
Show InChI InChI=1S/C15H17NO3S/c1-11-5-4-6-12(2)15(11)16-20(17,18)14-9-7-13(19-3)8-10-14/h4-10,16H,1-3H3
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n/an/an/an/a 3.16E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044853
PNG
(CHEMBL3311305)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C15H17NO3S/c1-11-4-9-15(12(2)10-11)16-20(17,18)14-7-5-13(19-3)6-8-14/h4-10,16H,1-3H3
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n/an/an/an/a 2.51E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044856
PNG
(CHEMBL3311313)
Show SMILES Cc1cc(C)c(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)c(C)c1
Show InChI InChI=1S/C16H16F3NO3S/c1-10-8-11(2)15(12(3)9-10)20-24(21,22)14-6-4-13(5-7-14)23-16(17,18)19/h4-9,20H,1-3H3
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n/an/an/an/a 1.26E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044858
PNG
(CHEMBL3311196)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(F)cc1C
Show InChI InChI=1S/C15H16FNO3S/c1-10-8-12(16)9-11(2)15(10)17-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,17H,1-3H3
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n/an/an/an/a 1.00E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044870
PNG
(CHEMBL3311198)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(OC)cc1C
Show InChI InChI=1S/C16H19NO4S/c1-11-9-14(21-4)10-12(2)16(11)17-22(18,19)15-7-5-13(20-3)6-8-15/h5-10,17H,1-4H3
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n/an/an/an/a 398n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044873
PNG
(CHEMBL3311327)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(CC=C)cc1C
Show InChI InChI=1S/C18H21NO3S/c1-5-6-15-11-13(2)18(14(3)12-15)19-23(20,21)17-9-7-16(22-4)8-10-17/h5,7-12,19H,1,6H2,2-4H3
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n/an/an/an/a 316n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044904
PNG
(CHEMBL3311307)
Show SMILES CCc1cccc(CC)c1NS(=O)(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C17H21NO3S/c1-4-13-7-6-8-14(5-2)17(13)18-22(19,20)16-11-9-15(21-3)10-12-16/h6-12,18H,4-5H2,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044909
PNG
(CHEMBL3311309)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(C)cc1C
Show InChI InChI=1S/C17H21NO3S/c1-12-10-13(2)17(14(3)11-12)18(4)22(19,20)16-8-6-15(21-5)7-9-16/h6-11H,1-5H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044918
PNG
(CHEMBL3311323)
Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C
Show InChI InChI=1S/C19H25NO3S/c1-5-6-11-23-17-7-9-18(10-8-17)24(21,22)20-19-15(3)12-14(2)13-16(19)4/h7-10,12-13,20H,5-6,11H2,1-4H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044919
PNG
(CHEMBL3311328)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(CC2CC2)cc1C
Show InChI InChI=1S/C19H23NO3S/c1-13-10-16(12-15-4-5-15)11-14(2)19(13)20-24(21,22)18-8-6-17(23-3)7-9-18/h6-11,15,20H,4-5,12H2,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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PCBioAssay
n/an/a 5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
Cathepsin (S and K)


(Homo sapiens (Human))
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (human))
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair