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24 similar compounds to monomer 50044849

Wt: 302.3
BDBM41345
Purchase
Wt: 331.3
BDBM71814
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Wt: 307.3
BDBM50441973
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Wt: 291.3
BDBM50441976
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Wt: 277.3
BDBM50441977
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Wt: 319.4
BDBM50044904
Purchase
Wt: 319.4
BDBM50044909
Wt: 347.4
BDBM50044918
Wt: 345.4
BDBM50044919
Wt: 291.3
BDBM50044851
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Wt: 291.3
BDBM50044853
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Wt: 359.3
BDBM50044856
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Wt: 309.3
BDBM50044858
Wt: 321.3
BDBM50044870
Wt: 331.4
BDBM50044873
Displayed 1 to 15 (of 24 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 41345,71814,50441973,50441976,50441977,50044904,50044909,50044918,50044919,50044851,50044853,50044856,50044858,50044870,50044873   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytohesin-2


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
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1.61E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cytohesin-2


(Homo sapiens)
BDBM50441976
PNG
(CHEMBL2440213)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO3S/c1-10-4-6-14(7-5-10)20(18,19)16-15-11(2)8-13(17)9-12(15)3/h4-9,16-17H,1-3H3
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1.91E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
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3.72E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hsf1 protein


(Mus musculus)
BDBM71814
PNG
(4-methoxy-N-[2-(trifluoromethyl)phenyl]benzenesulf...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(F)(F)F
Show InChI InChI=1S/C14H12F3NO3S/c1-21-10-6-8-11(9-7-10)22(19,20)18-13-5-3-2-4-12(13)14(15,16)17/h2-9,18H,1H3
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n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


Citation and Details
More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044851
PNG
(CHEMBL3311306)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cccc1C
Show InChI InChI=1S/C15H17NO3S/c1-11-5-4-6-12(2)15(11)16-20(17,18)14-9-7-13(19-3)8-10-14/h4-10,16H,1-3H3
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n/an/an/an/a 3.16E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044853
PNG
(CHEMBL3311305)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C15H17NO3S/c1-11-4-9-15(12(2)10-11)16-20(17,18)14-7-5-13(19-3)6-8-14/h4-10,16H,1-3H3
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n/an/an/an/a 2.51E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044856
PNG
(CHEMBL3311313)
Show SMILES Cc1cc(C)c(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)c(C)c1
Show InChI InChI=1S/C16H16F3NO3S/c1-10-8-11(2)15(12(3)9-10)20-24(21,22)14-6-4-13(5-7-14)23-16(17,18)19/h4-9,20H,1-3H3
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n/an/an/an/a 1.26E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044858
PNG
(CHEMBL3311196)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(F)cc1C
Show InChI InChI=1S/C15H16FNO3S/c1-10-8-12(16)9-11(2)15(10)17-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,17H,1-3H3
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n/an/an/an/a 1.00E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044870
PNG
(CHEMBL3311198)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(OC)cc1C
Show InChI InChI=1S/C16H19NO4S/c1-11-9-14(21-4)10-12(2)16(11)17-22(18,19)15-7-5-13(20-3)6-8-15/h5-10,17H,1-4H3
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n/an/an/an/a 398n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044873
PNG
(CHEMBL3311327)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(CC=C)cc1C
Show InChI InChI=1S/C18H21NO3S/c1-5-6-15-11-13(2)18(14(3)12-15)19-23(20,21)17-9-7-16(22-4)8-10-17/h5,7-12,19H,1,6H2,2-4H3
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n/an/an/an/a 316n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044904
PNG
(CHEMBL3311307)
Show SMILES CCc1cccc(CC)c1NS(=O)(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C17H21NO3S/c1-4-13-7-6-8-14(5-2)17(13)18-22(19,20)16-11-9-15(21-3)10-12-16/h6-12,18H,4-5H2,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044909
PNG
(CHEMBL3311309)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(C)cc1C
Show InChI InChI=1S/C17H21NO3S/c1-12-10-13(2)17(14(3)11-12)18(4)22(19,20)16-8-6-15(21-5)7-9-16/h6-11H,1-5H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044918
PNG
(CHEMBL3311323)
Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C
Show InChI InChI=1S/C19H25NO3S/c1-5-6-11-23-17-7-9-18(10-8-17)24(21,22)20-19-15(3)12-14(2)13-16(19)4/h7-10,12-13,20H,5-6,11H2,1-4H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50044919
PNG
(CHEMBL3311328)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(CC2CC2)cc1C
Show InChI InChI=1S/C19H23NO3S/c1-13-10-16(12-15-4-5-15)11-14(2)19(13)20-24(21,22)18-8-6-17(23-3)7-9-18/h6-11,15,20H,4-5,12H2,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
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n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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n/an/a 5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
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n/an/an/a 5.00E+5n/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cathepsin S


(Homo sapiens (Human))
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...


Citation and Details
More data for this
Ligand-Target Pair
Cathepsin L1


(Homo sapiens (human))
BDBM41345
PNG
(MLS000062036 | N-[4-(cyanomethyl)phenyl]-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CC#N)cc1
Show InChI InChI=1S/C15H14N2O3S/c1-20-14-6-8-15(9-7-14)21(18,19)17-13-4-2-12(3-5-13)10-11-16/h2-9,17H,10H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...


Citation and Details
More data for this
Ligand-Target Pair