Compounds in cluster

13 similar compounds to monomer 6474

Wt: 496.9 BDBM4547	Wt: 503.3 BDBM4549	Wt: 533.0 BDBM6460	Wt: 553.4 BDBM6462	Wt: 566.4 BDBM6463
Wt: 523.4 BDBM6468	Wt: 533.0 BDBM6469	Wt: 553.4 BDBM6471	Wt: 566.4 BDBM6472	Wt: 547.0 BDBM6475
Wt: 536.9 BDBM6476	Wt: 533.0 BDBM6465	Wt: 523.4 BDBM6480

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 4547,4549,6460,6462,6463,6468,6469,6471,6472,6475,6476,6465,6480
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4547 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2g \| ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
Wyeth-Ayerst Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4549 (4-Phenylamino 3-quinolinecarbonitrile deriv. 26 \| ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
Wyeth-Ayerst Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6460 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6462 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6463 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6465 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6471 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of c-SRC				Bioorg Med Chem 19: 2517-28 (2011) Article DOI: 10.1016/j.bmc.2011.03.021 BindingDB Entry DOI: 10.7270/Q2DN45CD
Institut de Recherches Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6469 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6471 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6472 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6475 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6476 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6480 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2989-92 (2002) Article DOI: 10.1016/s0960-894x(02)00577-2 BindingDB Entry DOI: 10.7270/Q24B2ZHC
Wyeth Research					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6468 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 48: 5909-20 (2005) Article DOI: 10.1021/jm050512u BindingDB Entry DOI: 10.7270/Q2833Q6N
Wyeth Research					More data for this Ligand-Target Pair