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3 similar compounds to monomer 39611

Compile data set for download or QSAR
Wt: 401.4
BDBM48794
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Wt: 427.5
BDBM73969
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Wt: 417.4
BDBM74536

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 48794,73969,74536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4


(Homo sapiens (Human))
BDBM48794
PNG
(3-(4-fluorophenyl)-1-[2-(2-methyl-1-piperidinyl)-2...)
Show SMILES CC1CCCCN1C(=O)Cn1c2ccsc2c(=O)n(-c2ccc(F)cc2)c1=O
Show InChI InChI=1S/C20H20FN3O3S/c1-13-4-2-3-10-22(13)17(25)12-23-16-9-11-28-18(16)19(26)24(20(23)27)15-7-5-14(21)6-8-15/h5-9,11,13H,2-4,10,12H2,1H3
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KEGG

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PC sid
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n/an/a 5.00E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2RN3686
More data for this
Ligand-Target Pair
LANA


(Human herpesvirus 8)
BDBM73969
PNG
(MLS000950288 | N-cyclohexyl-2-(2,4-diketo-3-p-phen...)
Show SMILES CCOc1ccc(cc1)-n1c(=O)n(CC(=O)NC2CCCCC2)c2ccsc2c1=O
Show InChI InChI=1S/C22H25N3O4S/c1-2-29-17-10-8-16(9-11-17)25-21(27)20-18(12-13-30-20)24(22(25)28)14-19(26)23-15-6-4-3-5-7-15/h8-13,15H,2-7,14H2,1H3,(H,23,26)
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n/an/an/an/a>7.50E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2HH6HHN
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM74536
PNG
(2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...)
Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O
Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)
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n/an/a>7.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CR5RTC
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM74536
PNG
(2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...)
Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O
Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)
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n/an/a>7.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VQ314Z
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM74536
PNG
(2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...)
Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O
Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)
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n/an/a>7.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24748BK
More data for this
Ligand-Target Pair