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2 similar compounds to monomer 46858

Compile data set for download or QSAR
Wt: 141.1
BDBM50000107
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Wt: 141.1
BDBM50024984
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000107,50024984   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50000107
PNG
(1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic ...)
Show SMILES CN1CCC=C(C1)C(O)=O
Show InChI InChI=1S/C7H11NO2/c1-8-4-2-3-6(5-8)7(9)10/h3H,2,4-5H2,1H3,(H,9,10)
PDB

UniProtKB/SwissProt

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CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.94E+5n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1


J Med Chem 35: 233-41 (1992)


Article DOI: 10.1021/jm00080a006
BindingDB Entry DOI: 10.7270/Q26W9911
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50024984
PNG
(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Show SMILES COC(=O)C1=CCCNC1
Show InChI InChI=1S/C7H11NO2/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lung


J Med Chem 29: 1004-9 (1986)


Article DOI: 10.1021/jm00156a018
BindingDB Entry DOI: 10.7270/Q2XP73XW
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50024984
PNG
(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Show SMILES COC(=O)C1=CCCNC1
Show InChI InChI=1S/C7H11NO2/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 300n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropine


J Med Chem 29: 1004-9 (1986)


Article DOI: 10.1021/jm00156a018
BindingDB Entry DOI: 10.7270/Q2XP73XW
More data for this
Ligand-Target Pair