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2 similar compounds to monomer 50001623

Compile data set for download or QSAR
Wt: 421.9
BDBM50001620
Wt: 359.4
BDBM50001631

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001620,50001631   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(Homo sapiens (Human))
BDBM50001620
PNG
(4-(4-Chloro-phenyl)-2-[5-methyl-5-(1H-tetrazol-5-y...)
Show SMILES CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1
Show InChI InChI=1S/C23H24ClN5O/c1-23(2,22-26-28-29-27-22)13-5-6-14-30-21-15-19(16-9-11-17(24)12-10-16)18-7-3-4-8-20(18)25-21/h3-4,7-12,15H,5-6,13-14H2,1-2H3,(H,26,27,28,29)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes


J Med Chem 35: 4306-14 (1992)


Article DOI: 10.1021/jm00101a007
BindingDB Entry DOI: 10.7270/Q2VH5MS6
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50001620
PNG
(4-(4-Chloro-phenyl)-2-[5-methyl-5-(1H-tetrazol-5-y...)
Show SMILES CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1
Show InChI InChI=1S/C23H24ClN5O/c1-23(2,22-26-28-29-27-22)13-5-6-14-30-21-15-19(16-9-11-17(24)12-10-16)18-7-3-4-8-20(18)25-21/h3-4,7-12,15H,5-6,13-14H2,1-2H3,(H,26,27,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes


J Med Chem 35: 4306-14 (1992)


Article DOI: 10.1021/jm00101a007
BindingDB Entry DOI: 10.7270/Q2VH5MS6
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50001631
PNG
(4-Phenyl-2-[5-(1H-tetrazol-5-yl)-pentyloxy]-quinol...)
Show SMILES C(CCOc1cc(-c2ccccc2)c2ccccc2n1)CCc1nnn[nH]1
Show InChI InChI=1S/C21H21N5O/c1-3-9-16(10-4-1)18-15-21(22-19-12-7-6-11-17(18)19)27-14-8-2-5-13-20-23-25-26-24-20/h1,3-4,6-7,9-12,15H,2,5,8,13-14H2,(H,23,24,25,26)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes


J Med Chem 35: 4306-14 (1992)


Article DOI: 10.1021/jm00101a007
BindingDB Entry DOI: 10.7270/Q2VH5MS6
More data for this
Ligand-Target Pair