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3 similar compounds to monomer 50002468

Compile data set for download or QSAR
Wt: 488.1
BDBM50002466
Wt: 462.1
BDBM50002467
Wt: 447.1
BDBM50002469

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002466,50002467,50002469   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002469
PNG
(ddTMPNPPDideoxythymidine 5'-[alpha,beta-imido]trip...)
Show SMILES Cc1cn([C@H]2CC[C@@H](OP([O-])(=O)NP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C9H16N3O12P3/c1-5-4-12(9(14)10-8(5)13)6-2-3-7(22-6)23-25(15,16)11-26(17,18)24-27(19,20)21/h4,6-7H,2-3H2,1H3,(H,10,13,14)(H2,19,20,21)(H3,11,15,16,17,18)/p-4/t6-,7-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.50E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).


J Med Chem 35: 1938-41 (1992)


Article DOI: 10.1021/jm00089a002
BindingDB Entry DOI: 10.7270/Q25B0336
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002467
PNG
(TMPNPNPthymidine 5'-[alpha,beta:beta,alpha-diimido...)
Show SMILES Cc1cn([C@H]2C[C@@H](O)[C@@H](OP([O-])(=O)NP([O-])(=O)NP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C9H17N4O12P3/c1-4-3-13(9(16)10-7(4)15)6-2-5(14)8(24-6)25-28(22,23)12-26(17,18)11-27(19,20)21/h3,5-6,8,14H,2H2,1H3,(H,10,15,16)(H6,11,12,17,18,19,20,21,22,23)/p-4/t5-,6-,8-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.91E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).


J Med Chem 35: 1938-41 (1992)


Article DOI: 10.1021/jm00089a002
BindingDB Entry DOI: 10.7270/Q25B0336
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002466
PNG
(AZTMPNPP3'-azido-3'-deoxythymidine 5'-[alpha,beta-...)
Show SMILES Cc1cn([C@H]2C[C@@H](N=[N+]=[N-])[C@@H](OP([O-])(=O)NP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C9H15N6O12P3/c1-4-3-15(9(17)11-7(4)16)6-2-5(12-13-10)8(25-6)26-28(18,19)14-29(20,21)27-30(22,23)24/h3,5-6,8H,2H2,1H3,(H,11,16,17)(H2,22,23,24)(H3,14,18,19,20,21)/p-4/t5-,6-,8-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).


J Med Chem 35: 1938-41 (1992)


Article DOI: 10.1021/jm00089a002
BindingDB Entry DOI: 10.7270/Q25B0336
More data for this
Ligand-Target Pair