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29 similar compounds to monomer 50044038

Compile data set for download or QSAR
Wt: 840.9
BDBM50002515
Wt: 782.8
BDBM50453649
Wt: 803.3
BDBM50453648
Wt: 854.9
BDBM50040520
Wt: 854.9
BDBM50040521
Wt: 740.8
BDBM50040522
Wt: 840.9
BDBM50040523
Wt: 754.8
BDBM50040524
Wt: 782.8
BDBM50044022
Wt: 839.9
BDBM50044024
Wt: 798.8
BDBM50044025
Wt: 858.9
BDBM50044026
Wt: 917.1
BDBM50044027
Wt: 826.9
BDBM50044028
Wt: 825.9
BDBM50044029
Displayed 1 to 15 (of 29 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50002515,50453649,50453648,50040520,50040521,50040522,50040523,50040524,50044022,50044024,50044025,50044026,50044027,50044028,50044029   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CCKBR


(GUINEA PIG)
BDBM50002515
PNG
((A-71623)3-[2-[2-tert-Butoxycarbonylamino-3-(1H-in...)
Show SMILES CN(C(Cc1ccccc1)C(N)=O)C(=O)C(CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(39(56)49-35(25-37(53)54)41(58)52(5)36(38(45)55)23-28-16-7-6-8-17-28)48-40(57)34(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,57)(H,49,56)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34?,35?,36?/m0/s1
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3.70n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 39: 346-51 (1991)


BindingDB Entry DOI: 10.7270/Q2222S8S
More data for this
Ligand-Target Pair
CCKBR


(GUINEA PIG)
BDBM50002515
PNG
((A-71623)3-[2-[2-tert-Butoxycarbonylamino-3-(1H-in...)
Show SMILES CN(C(Cc1ccccc1)C(N)=O)C(=O)C(CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(39(56)49-35(25-37(53)54)41(58)52(5)36(38(45)55)23-28-16-7-6-8-17-28)48-40(57)34(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,57)(H,49,56)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34?,35?,36?/m0/s1
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4.50E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 39: 346-51 (1991)


BindingDB Entry DOI: 10.7270/Q2222S8S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50453648
PNG
(CHEMBL63707)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(CCCCNC(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O
Show InChI InChI=1S/C40H47ClN8O8/c1-23-14-16-25(17-15-23)19-32(36(42)53)47-39(56)34(21-35(51)52)48-37(54)31(13-7-8-18-43-40(57)49-30-12-6-4-10-28(30)41)46-38(55)33(45-24(2)50)20-26-22-44-29-11-5-3-9-27(26)29/h3-6,9-12,14-17,22,31-34,44H,7-8,13,18-21H2,1-2H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,56)(H,48,54)(H,51,52)(H2,43,49,57)/t31?,32-,33+,34+/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes


J Med Chem 38: 207-11 (1995)


Article DOI: 10.1021/jm00001a027
BindingDB Entry DOI: 10.7270/Q28C9XF9
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50453649
PNG
(CHEMBL304524)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O
Show InChI InChI=1S/C41H50N8O8/c1-24-15-17-27(18-16-24)20-33(37(42)53)47-40(56)35(22-36(51)52)48-38(54)32(14-8-9-19-43-41(57)49-30-12-6-4-10-25(30)2)46-39(55)34(45-26(3)50)21-28-23-44-31-13-7-5-11-29(28)31/h4-7,10-13,15-18,23,32-35,44H,8-9,14,19-22H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,56)(H,48,54)(H,51,52)(H2,43,49,57)/t32?,33-,34+,35+/m1/s1
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n/an/a 5.01E+3n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes


J Med Chem 38: 207-11 (1995)


Article DOI: 10.1021/jm00001a027
BindingDB Entry DOI: 10.7270/Q28C9XF9
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50453649
PNG
(CHEMBL304524)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O
Show InChI InChI=1S/C41H50N8O8/c1-24-15-17-27(18-16-24)20-33(37(42)53)47-40(56)35(22-36(51)52)48-38(54)32(14-8-9-19-43-41(57)49-30-12-6-4-10-25(30)2)46-39(55)34(45-26(3)50)21-28-23-44-31-13-7-5-11-29(28)31/h4-7,10-13,15-18,23,32-35,44H,8-9,14,19-22H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,56)(H,48,54)(H,51,52)(H2,43,49,57)/t32?,33-,34+,35+/m1/s1
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n/an/a 20n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Displacement of CCK-8 from CHO cell membranes expressing human Cholecystokinin type A receptor


J Med Chem 38: 207-11 (1995)


Article DOI: 10.1021/jm00001a027
BindingDB Entry DOI: 10.7270/Q28C9XF9
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50453648
PNG
(CHEMBL63707)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(CCCCNC(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O
Show InChI InChI=1S/C40H47ClN8O8/c1-23-14-16-25(17-15-23)19-32(36(42)53)47-39(56)34(21-35(51)52)48-37(54)31(13-7-8-18-43-40(57)49-30-12-6-4-10-28(30)41)46-38(55)33(45-24(2)50)20-26-22-44-29-11-5-3-9-27(26)29/h3-6,9-12,14-17,22,31-34,44H,7-8,13,18-21H2,1-2H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,56)(H,48,54)(H,51,52)(H2,43,49,57)/t31?,32-,33+,34+/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Displacement of CCK-8 from CHO cell membranes expressing human Cholecystokinin type A receptor


J Med Chem 38: 207-11 (1995)


Article DOI: 10.1021/jm00001a027
BindingDB Entry DOI: 10.7270/Q28C9XF9
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044024
PNG
((S)-3-[(S)-2-[2-((S)-3-tert-Butyl-ureido)-3-(1H-in...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NC(C)(C)C
Show InChI InChI=1S/C44H57N9O8/c1-27-15-9-11-19-31(27)50-42(60)46-22-14-13-21-33(39(57)49-35(25-37(54)55)41(59)53(5)36(38(45)56)23-28-16-7-6-8-17-28)48-40(58)34(51-43(61)52-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,56)(H,48,58)(H,49,57)(H,54,55)(H2,46,50,60)(H2,51,52,61)/t33-,34-,35-,36-/m0/s1
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n/an/a 5.40n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044028
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((...)
Show SMILES CC(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H54N8O9/c1-26(2)60-43(59)50-34(23-29-25-46-32-19-11-9-17-30(29)32)40(56)47-33(20-12-13-21-45-42(58)49-31-18-10-8-14-27(31)3)39(55)48-35(24-37(52)53)41(57)51(4)36(38(44)54)22-28-15-6-5-7-16-28/h5-11,14-19,25-26,33-36,46H,12-13,20-24H2,1-4H3,(H2,44,54)(H,47,56)(H,48,55)(H,50,59)(H,52,53)(H2,45,49,58)/t33-,34-,35-,36-/m0/s1
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n/an/a 1.60n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044026
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C47H54N8O8/c1-30-15-9-11-21-35(30)54-47(63)49-24-14-13-23-37(44(60)53-39(28-42(57)58)46(62)55(2)40(43(48)59)25-31-16-5-3-6-17-31)52-45(61)38(51-41(56)26-32-18-7-4-8-19-32)27-33-29-50-36-22-12-10-20-34(33)36/h3-12,15-22,29,37-40,50H,13-14,23-28H2,1-2H3,(H2,48,59)(H,51,56)(H,52,61)(H,53,60)(H,57,58)(H2,49,54,63)/t37-,38-,39-,40-/m0/s1
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n/an/a 18n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044022
PNG
((S)-3-[(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C41H50N8O8/c1-25-13-7-9-17-30(25)48-41(57)43-20-12-11-19-32(46-39(55)33(45-26(2)50)22-28-24-44-31-18-10-8-16-29(28)31)38(54)47-34(23-36(51)52)40(56)49(3)35(37(42)53)21-27-14-5-4-6-15-27/h4-10,13-18,24,32-35,44H,11-12,19-23H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,54)(H,51,52)(H2,43,48,57)/t32-,33-,34-,35-/m0/s1
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n/an/a 4.80n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044025
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(...)
Show SMILES COC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C41H50N8O9/c1-25-13-7-9-17-29(25)47-40(56)43-20-12-11-19-31(45-38(54)32(48-41(57)58-3)22-27-24-44-30-18-10-8-16-28(27)30)37(53)46-33(23-35(50)51)39(55)49(2)34(36(42)52)21-26-14-5-4-6-15-26/h4-10,13-18,24,31-34,44H,11-12,19-23H2,1-3H3,(H2,42,52)(H,45,54)(H,46,53)(H,48,57)(H,50,51)(H2,43,47,56)/t31-,32-,33-,34-/m0/s1
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n/an/a 3.90n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044029
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(...)
Show SMILES CN(C)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H55N9O8/c1-27-14-8-10-18-31(27)50-43(60)45-21-13-12-20-33(48-41(58)34(47-37(53)26-51(2)3)23-29-25-46-32-19-11-9-17-30(29)32)40(57)49-35(24-38(54)55)42(59)52(4)36(39(44)56)22-28-15-6-5-7-16-28/h5-11,14-19,25,33-36,46H,12-13,20-24,26H2,1-4H3,(H2,44,56)(H,47,53)(H,48,58)(H,49,57)(H,54,55)(H2,45,50,60)/t33-,34-,35-,36-/m0/s1
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n/an/a 11n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50044027
PNG
((S)-3-[(S)-2-[(S)-2-(2-Adamantan-1-yl-acetylamino)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C51H64N8O8/c1-31-12-6-8-16-38(31)58-50(67)53-19-11-10-18-40(47(64)57-42(25-45(61)62)49(66)59(2)43(46(52)63)23-32-13-4-3-5-14-32)56-48(65)41(24-36-30-54-39-17-9-7-15-37(36)39)55-44(60)29-51-26-33-20-34(27-51)22-35(21-33)28-51/h3-9,12-17,30,33-35,40-43,54H,10-11,18-29H2,1-2H3,(H2,52,63)(H,55,60)(H,56,65)(H,57,64)(H,61,62)(H2,53,58,67)/t33?,34?,35?,40-,41-,42-,43-,51?/m0/s1
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n/an/a 19n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 3.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040522
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(...)
Show SMILES CN[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C39H48N8O7/c1-24-12-6-8-16-28(24)47-39(54)42-19-11-10-18-30(44-37(52)32(41-2)21-26-23-43-29-17-9-7-15-27(26)29)36(51)46-33(22-34(48)49)38(53)45-31(35(40)50)20-25-13-4-3-5-14-25/h3-9,12-17,23,30-33,41,43H,10-11,18-22H2,1-2H3,(H2,40,50)(H,44,52)(H,45,53)(H,46,51)(H,48,49)(H2,42,47,54)/t30-,31-,32-,33-/m0/s1
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n/an/a 16n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044022
PNG
((S)-3-[(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C41H50N8O8/c1-25-13-7-9-17-30(25)48-41(57)43-20-12-11-19-32(46-39(55)33(45-26(2)50)22-28-24-44-31-18-10-8-16-29(28)31)38(54)47-34(23-36(51)52)40(56)49(3)35(37(42)53)21-27-14-5-4-6-15-27/h4-10,13-18,24,32-35,44H,11-12,19-23H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,54)(H,51,52)(H2,43,48,57)/t32-,33-,34-,35-/m0/s1
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n/an/a 20n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type A receptor expressed in CHO-K1 cells


J Med Chem 38: 3384-90 (1995)


Article DOI: 10.1021/jm00017a022
BindingDB Entry DOI: 10.7270/Q2KP83FW
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.30n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040521
PNG
((S)-3-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...)
Show SMILES CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H58N8O9/c1-28-16-10-12-20-32(28)51-43(60)46-23-15-14-22-34(48-40(57)35(52-44(61)62-45(2,3)4)25-30-27-47-33-21-13-11-19-31(30)33)39(56)49-36(26-38(54)55)41(58)50-37(42(59)53(5)6)24-29-17-8-7-9-18-29/h7-13,16-21,27,34-37,47H,14-15,22-26H2,1-6H3,(H,48,57)(H,49,56)(H,50,58)(H,52,61)(H,54,55)(H2,46,51,60)/t34-,35-,36-,37-/m0/s1
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n/an/a 117n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040520
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H58N8O9/c1-28-16-10-12-20-32(28)50-43(60)47-23-15-14-22-34(49-40(57)35(51-44(61)62-45(2,3)4)25-30-27-48-33-21-13-11-19-31(30)33)41(58)53(6)37(26-38(54)55)42(59)52(5)36(39(46)56)24-29-17-8-7-9-18-29/h7-13,16-21,27,34-37,48H,14-15,22-26H2,1-6H3,(H2,46,56)(H,49,57)(H,51,61)(H,54,55)(H2,47,50,60)/t34-,35-,36-,37-/m0/s1
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n/an/a 5.30n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK-8 from Cholecystokinin type B receptor of guinea pig cortex


J Med Chem 33: 2950-2 (1990)


Article DOI: 10.1021/jm00173a006
BindingDB Entry DOI: 10.7270/Q2M32WCP
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex


J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040520
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H58N8O9/c1-28-16-10-12-20-32(28)50-43(60)47-23-15-14-22-34(49-40(57)35(51-44(61)62-45(2,3)4)25-30-27-48-33-21-13-11-19-31(30)33)41(58)53(6)37(26-38(54)55)42(59)52(5)36(39(46)56)24-29-17-8-7-9-18-29/h7-13,16-21,27,34-37,48H,14-15,22-26H2,1-6H3,(H2,46,56)(H,49,57)(H,51,61)(H,54,55)(H2,47,50,60)/t34-,35-,36-,37-/m0/s1
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n/an/a 427n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040521
PNG
((S)-3-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...)
Show SMILES CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H58N8O9/c1-28-16-10-12-20-32(28)51-43(60)46-23-15-14-22-34(48-40(57)35(52-44(61)62-45(2,3)4)25-30-27-47-33-21-13-11-19-31(30)33)39(56)49-36(26-38(54)55)41(58)50-37(42(59)53(5)6)24-29-17-8-7-9-18-29/h7-13,16-21,27,34-37,47H,14-15,22-26H2,1-6H3,(H,48,57)(H,49,56)(H,50,58)(H,52,61)(H,54,55)(H2,46,51,60)/t34-,35-,36-,37-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040524
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-{[(S)-2-[...)
Show SMILES CN[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N(C)[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C40H50N8O7/c1-25-13-7-9-17-29(25)47-40(55)43-20-12-11-19-31(45-37(52)33(42-2)22-27-24-44-30-18-10-8-16-28(27)30)39(54)48(3)34(23-35(49)50)38(53)46-32(36(41)51)21-26-14-5-4-6-15-26/h4-10,13-18,24,31-34,42,44H,11-12,19-23H2,1-3H3,(H2,41,51)(H,45,52)(H,46,53)(H,49,50)(H2,43,47,55)/t31-,32-,33-,34-/m0/s1
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n/an/a 6.92E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040522
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(...)
Show SMILES CN[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C39H48N8O7/c1-24-12-6-8-16-28(24)47-39(54)42-19-11-10-18-30(44-37(52)32(41-2)21-26-23-43-29-17-9-7-15-27(26)29)36(51)46-33(22-34(48)49)38(53)45-31(35(40)50)20-25-13-4-3-5-14-25/h3-9,12-17,23,30-33,41,43H,10-11,18-22H2,1-2H3,(H2,40,50)(H,44,52)(H,45,53)(H,46,51)(H,48,49)(H2,42,47,54)/t30-,31-,32-,33-/m0/s1
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n/an/a 3.72E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type B receptor in guinea pig cortex


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044024
PNG
((S)-3-[(S)-2-[2-((S)-3-tert-Butyl-ureido)-3-(1H-in...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NC(C)(C)C
Show InChI InChI=1S/C44H57N9O8/c1-27-15-9-11-19-31(27)50-42(60)46-22-14-13-21-33(39(57)49-35(25-37(54)55)41(59)53(5)36(38(45)56)23-28-16-7-6-8-17-28)48-40(58)34(51-43(61)52-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,56)(H,48,58)(H,49,57)(H,54,55)(H2,46,50,60)(H2,51,52,61)/t33-,34-,35-,36-/m0/s1
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n/an/a 3.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044025
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(...)
Show SMILES COC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C41H50N8O9/c1-25-13-7-9-17-29(25)47-40(56)43-20-12-11-19-31(45-38(54)32(48-41(57)58-3)22-27-24-44-30-18-10-8-16-28(27)30)37(53)46-33(23-35(50)51)39(55)49(2)34(36(42)52)21-26-14-5-4-6-15-26/h4-10,13-18,24,31-34,44H,11-12,19-23H2,1-3H3,(H2,42,52)(H,45,54)(H,46,53)(H,48,57)(H,50,51)(H2,43,47,56)/t31-,32-,33-,34-/m0/s1
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n/an/a 5.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044026
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C47H54N8O8/c1-30-15-9-11-21-35(30)54-47(63)49-24-14-13-23-37(44(60)53-39(28-42(57)58)46(62)55(2)40(43(48)59)25-31-16-5-3-6-17-31)52-45(61)38(51-41(56)26-32-18-7-4-8-19-32)27-33-29-50-36-22-12-10-20-34(33)36/h3-12,15-22,29,37-40,50H,13-14,23-28H2,1-2H3,(H2,48,59)(H,51,56)(H,52,61)(H,53,60)(H,57,58)(H2,49,54,63)/t37-,38-,39-,40-/m0/s1
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n/an/a 7.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044022
PNG
((S)-3-[(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C41H50N8O8/c1-25-13-7-9-17-30(25)48-41(57)43-20-12-11-19-32(46-39(55)33(45-26(2)50)22-28-24-44-31-18-10-8-16-29(28)31)38(54)47-34(23-36(51)52)40(56)49(3)35(37(42)53)21-27-14-5-4-6-15-27/h4-10,13-18,24,32-35,44H,11-12,19-23H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,54)(H,51,52)(H2,43,48,57)/t32-,33-,34-,35-/m0/s1
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n/an/a 6.40E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044028
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((...)
Show SMILES CC(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H54N8O9/c1-26(2)60-43(59)50-34(23-29-25-46-32-19-11-9-17-30(29)32)40(56)47-33(20-12-13-21-45-42(58)49-31-18-10-8-14-27(31)3)39(55)48-35(24-37(52)53)41(57)51(4)36(38(44)54)22-28-15-6-5-7-16-28/h5-11,14-19,25-26,33-36,46H,12-13,20-24H2,1-4H3,(H2,44,54)(H,47,56)(H,48,55)(H,50,59)(H,52,53)(H2,45,49,58)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of specific binding to Cholecystokinin type B receptor in guinea pig cortex using [125I]Bolton-Hunter CCK-8


J Med Chem 37: 309-13 (1994)


Article DOI: 10.1021/jm00028a015
BindingDB Entry DOI: 10.7270/Q2445N4S
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50044022
PNG
((S)-3-[(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C41H50N8O8/c1-25-13-7-9-17-30(25)48-41(57)43-20-12-11-19-32(46-39(55)33(45-26(2)50)22-28-24-44-31-18-10-8-16-29(28)31)38(54)47-34(23-36(51)52)40(56)49(3)35(37(42)53)21-27-14-5-4-6-15-27/h4-10,13-18,24,32-35,44H,11-12,19-23H2,1-3H3,(H2,42,53)(H,45,50)(H,46,55)(H,47,54)(H,51,52)(H2,43,48,57)/t32-,33-,34-,35-/m0/s1
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n/an/a 5.01E+3n/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cells


J Med Chem 38: 3384-90 (1995)


Article DOI: 10.1021/jm00017a022
BindingDB Entry DOI: 10.7270/Q2KP83FW
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 3.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK-8 from Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 33: 2950-2 (1990)


Article DOI: 10.1021/jm00173a006
BindingDB Entry DOI: 10.7270/Q2M32WCP
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 3.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.


J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50040524
PNG
((S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-{[(S)-2-[...)
Show SMILES CN[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N(C)[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C40H50N8O7/c1-25-13-7-9-17-29(25)47-40(55)43-20-12-11-19-31(45-37(52)33(42-2)22-27-24-44-30-18-10-8-16-28(27)30)39(54)48(3)34(23-35(49)50)38(53)46-32(36(41)51)21-26-14-5-4-6-15-26/h4-10,13-18,24,31-34,42,44H,11-12,19-23H2,1-3H3,(H2,41,51)(H,45,52)(H,46,53)(H,49,50)(H2,43,47,55)/t31-,32-,33-,34-/m0/s1
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas


J Med Chem 37: 630-5 (1994)


Article DOI: 10.1021/jm00031a013
BindingDB Entry DOI: 10.7270/Q23X878C
More data for this
Ligand-Target Pair