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2 similar compounds to monomer 50003534

Compile data set for download or QSAR
Wt: 444.3
BDBM50003507
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Wt: 385.4
BDBM50003540
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003507,50003540   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003540
PNG
(CHEMBL541330 | [4-(Pyridine-3-carbonyl)-piperazin-...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCN(CC1)C(=O)c1cccnc1
Show InChI InChI=1S/C20H23N3O5/c1-26-16-11-15(12-17(27-2)18(16)28-3)20(25)23-9-7-22(8-10-23)19(24)14-5-4-6-21-13-14/h4-6,11-13H,7-10H2,1-3H3
MMDB

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003507
PNG
((4-Pyridin-3-ylmethyl-piperazin-1-yl)-(3,4,5-trime...)
Show SMILES Cl.Cl.COc1cc(cc(OC)c1OC)C(=O)N1CCN(Cc2cccnc2)CC1
Show InChI InChI=1S/C20H25N3O4/c1-25-17-11-16(12-18(26-2)19(17)27-3)20(24)23-9-7-22(8-10-23)14-15-5-4-6-21-13-15/h4-6,11-13H,7-10,14H2,1-3H3
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair