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7 similar compounds to monomer 50004295

Compile data set for download or QSAR
Wt: 396.5
BDBM50004271
Wt: 354.4
BDBM50004279
Wt: 340.4
BDBM50004282
Wt: 368.4
BDBM50004284
Wt: 326.3
BDBM50004286
Wt: 368.4
BDBM50004288
Wt: 354.4
BDBM50004292

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004271,50004279,50004282,50004284,50004286,50004288,50004292   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004292
PNG
(2-Isopropoxy-quinoline-4-carboxylic acid 8-methyl-...)
Show SMILES CC(C)Oc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C21H26N2O3/c1-13(2)25-20-12-18(17-6-4-5-7-19(17)22-20)21(24)26-16-10-14-8-9-15(11-16)23(14)3/h4-7,12-16H,8-11H2,1-3H3
PDB

UniProtKB/SwissProt

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CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.310n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004279
PNG
(2-Propoxy-quinoline-4-carboxylic acid 8-methyl-8-a...)
Show SMILES CCCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C21H26N2O3/c1-3-10-25-20-13-18(17-6-4-5-7-19(17)22-20)21(24)26-16-11-14-8-9-15(12-16)23(14)2/h4-7,13-16H,3,8-12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.320n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004288
PNG
(2-Butoxy-quinoline-4-carboxylic acid 8-methyl-8-az...)
Show SMILES CCCCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C22H28N2O3/c1-3-4-11-26-21-14-19(18-7-5-6-8-20(18)23-21)22(25)27-17-12-15-9-10-16(13-17)24(15)2/h5-8,14-17H,3-4,9-13H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.390n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004284
PNG
(2-Isobutoxy-quinoline-4-carboxylic acid 8-methyl-8...)
Show SMILES CC(C)COc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C22H28N2O3/c1-14(2)13-26-21-12-19(18-6-4-5-7-20(18)23-21)22(25)27-17-10-15-8-9-16(11-17)24(15)3/h4-7,12,14-17H,8-11,13H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.440n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004286
PNG
(2-Methoxy-quinoline-4-carboxylic acid 8-methyl-8-a...)
Show SMILES COc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C19H22N2O3/c1-21-12-7-8-13(21)10-14(9-12)24-19(22)16-11-18(23-2)20-17-6-4-3-5-15(16)17/h3-6,11-14H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.580n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004282
PNG
(2-Ethoxy-quinoline-4-carboxylic acid 8-methyl-8-az...)
Show SMILES CCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C20H24N2O3/c1-3-24-19-12-17(16-6-4-5-7-18(16)21-19)20(23)25-15-10-13-8-9-14(11-15)22(13)2/h4-7,12-15H,3,8-11H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.880n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004271
PNG
(2-Hexyloxy-quinoline-4-carboxylic acid 8-methyl-8-...)
Show SMILES CCCCCCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C24H32N2O3/c1-3-4-5-8-13-28-23-16-21(20-9-6-7-10-22(20)25-23)24(27)29-19-14-17-11-12-18(15-19)26(17)2/h6-7,9-10,16-19H,3-5,8,11-15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.20n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair