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4 similar compounds to monomer 50008016

Compile data set for download or QSAR
Wt: 359.2
BDBM50008008
Wt: 420.1
BDBM50008012
Wt: 355.2
BDBM50008017
Wt: 375.6
BDBM50008019

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008008,50008012,50008017,50008019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50008008
PNG
(5-Fluoro-1-(2-hydroxy-ethoxymethyl)-6-phenylselany...)
Show SMILES OCCOCn1c([Se]c2ccccc2)c(F)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H13FN2O4Se/c14-10-11(18)15-13(19)16(8-20-7-6-17)12(10)21-9-4-2-1-3-5-9/h1-5,17H,6-8H2,(H,15,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells


J Med Chem 34: 3305-9 (1991)


Article DOI: 10.1021/jm00115a022
BindingDB Entry DOI: 10.7270/Q2DR2TFF
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50008019
PNG
(5-Chloro-1-(2-hydroxy-ethoxymethyl)-6-phenylselany...)
Show SMILES OCCOCn1c([Se]c2ccccc2)c(Cl)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H13ClN2O4Se/c14-10-11(18)15-13(19)16(8-20-7-6-17)12(10)21-9-4-2-1-3-5-9/h1-5,17H,6-8H2,(H,15,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells


J Med Chem 34: 3305-9 (1991)


Article DOI: 10.1021/jm00115a022
BindingDB Entry DOI: 10.7270/Q2DR2TFF
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50008012
PNG
(5-Bromo-1-(2-hydroxy-ethoxymethyl)-6-phenylselanyl...)
Show SMILES OCCOCn1c([Se]c2ccccc2)c(Br)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H13BrN2O4Se/c14-10-11(18)15-13(19)16(8-20-7-6-17)12(10)21-9-4-2-1-3-5-9/h1-5,17H,6-8H2,(H,15,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells


J Med Chem 34: 3305-9 (1991)


Article DOI: 10.1021/jm00115a022
BindingDB Entry DOI: 10.7270/Q2DR2TFF
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50008017
PNG
(1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylselany...)
Show SMILES Cc1c([Se]c2ccccc2)n(COCCO)c(=O)[nH]c1=O
Show InChI InChI=1S/C14H16N2O4Se/c1-10-12(18)15-14(19)16(9-20-8-7-17)13(10)21-11-5-3-2-4-6-11/h2-6,17H,7-9H2,1H3,(H,15,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.03E+4n/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells


J Med Chem 34: 3305-9 (1991)


Article DOI: 10.1021/jm00115a022
BindingDB Entry DOI: 10.7270/Q2DR2TFF
More data for this
Ligand-Target Pair