BindingDB logo
myBDB logout

3 similar compounds to monomer 50010074

Compile data set for download or QSAR
Wt: 421.4
BDBM50010073
Wt: 421.4
BDBM50010076
Wt: 435.5
BDBM50010077

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010073,50010076,50010077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010073
PNG
(3-(2-{3-[(E)-Phenylcarbamoylmethylimino-amino]-7-o...)
Show SMILES OC(=O)CCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C24H27N3O4/c28-23(29)13-10-16-6-4-5-7-17(16)14-19-20(22-12-11-21(19)31-22)15-25-27-24(30)26-18-8-2-1-3-9-18/h1-9,15,19-22H,10-14H2,(H,28,29)(H2,26,27,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010076
PNG
(CHEMBL99348 | {3-[2-(5-oxabicyclo[2.2.1],3-formald...)
Show SMILES OC(=O)Cc1cccc(CCC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C24H27N3O4/c28-23(29)14-17-6-4-5-16(13-17)9-10-19-20(22-12-11-21(19)31-22)15-25-27-24(30)26-18-7-2-1-3-8-18/h1-8,13,15,19-22H,9-12,14H2,(H,28,29)(H2,26,27,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.07E+3n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010077
PNG
(4-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinoc...)
Show SMILES OC(=O)CCCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C25H29N3O4/c29-24(30)12-6-9-17-7-4-5-8-18(17)15-20-21(23-14-13-22(20)32-23)16-26-28-25(31)27-19-10-2-1-3-11-19/h1-5,7-8,10-11,16,20-23H,6,9,12-15H2,(H,29,30)(H2,27,28,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 21n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair