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2 similar compounds to monomer 50010073

Compile data set for download or QSAR
Wt: 407.4
BDBM50010074
Wt: 435.5
BDBM50010077

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010074,50010077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010077
PNG
(4-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinoc...)
Show SMILES OC(=O)CCCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1
Show InChI InChI=1S/C25H29N3O4/c29-24(30)12-6-9-17-7-4-5-8-18(17)15-20-21(23-14-13-22(20)32-23)16-26-28-25(31)27-19-10-2-1-3-11-19/h1-5,7-8,10-11,16,20-23H,6,9,12-15H2,(H,29,30)(H2,27,28,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 21n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010074
PNG
(CHEMBL99041 | [3-(5-oxabicyclo[2.2.1],3-formaldehy...)
Show SMILES OC(=O)Cc1cccc(CC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C23H25N3O4/c27-22(28)13-16-6-4-5-15(11-16)12-18-19(21-10-9-20(18)30-21)14-24-26-23(29)25-17-7-2-1-3-8-17/h1-8,11,14,18-21H,9-10,12-13H2,(H,27,28)(H2,25,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 171n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair