BindingDB logo
myBDB logout

53 similar compounds to monomer 85049

Compile data set for download or QSAR
Wt: 231.3
BDBM50455999
Wt: 203.2
BDBM50452344
Wt: 245.3
BDBM50452345
Wt: 245.3
BDBM50452347
Wt: 245.3
BDBM50011246
Wt: 219.2
BDBM50010687
Wt: 245.3
BDBM50011248
Wt: 245.3
BDBM50011249
Wt: 245.3
BDBM50011251
Wt: 245.3
BDBM50011253
Wt: 245.3
BDBM50011255
Wt: 261.4
BDBM50011256
Wt: 261.4
BDBM50011257
Wt: 275.4
BDBM50011258
Wt: 261.4
BDBM50011262
Displayed 1 to 15 (of 52 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50455999,50452344,50452345,50452347,50011246,50010687,50011248,50011249,50011251,50011253,50011255,50011256,50011257,50011258,50011262   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011246
PNG
(4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...)
Show SMILES CCCN1CCC[C@@H]2[C@@H]1CCc1cccc(O)c21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011251
PNG
(4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...)
Show SMILES CCCN1CCC[C@H]2[C@H]1CCc1cccc(O)c21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
32n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011248
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@H]2Cc3cccc(O)c3C[C@@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
151n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
296n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011262
PNG
(7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@@H]1Cc2c(O)cccc2C[C@@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
394n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
656n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011257
PNG
(7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.39E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.02E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011249
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@@H]2Cc3cccc(O)c3C[C@@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.81E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011253
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@H]2Cc3cccc(O)c3C[C@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011258
PNG
(7-Dipropylamino-6,6-dimethyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)C1Cc2c(O)cccc2CC1(C)C
Show InChI InChI=1/C18H29NO/c1-5-10-19(11-6-2)17-12-15-14(13-18(17,3)4)8-7-9-16(15)20/h7-9,17,20H,5-6,10-13H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011255
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@@H]2Cc3cccc(O)c3C[C@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 774n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.42E+3n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 486n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.42E+3n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 486n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 416n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)


(Rattus norvegicus (rat))
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/s2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50010687
PNG
(1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinoline-8,9...)
Show SMILES Oc1cc2CC[C@H]3NCCC[C@@H]3c2cc1O
Show InChI InChI=1S/C13H17NO2/c15-12-6-8-3-4-11-9(2-1-5-14-11)10(8)7-13(12)16/h6-7,9,11,14-16H,1-5H2/t9-,11-/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum


J Med Chem 33: 1756-64 (1990)


Article DOI: 10.1021/jm00168a034
BindingDB Entry DOI: 10.7270/Q23X877X
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010687
PNG
(1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinoline-8,9...)
Show SMILES Oc1cc2CC[C@H]3NCCC[C@@H]3c2cc1O
Show InChI InChI=1S/C13H17NO2/c15-12-6-8-3-4-11-9(2-1-5-14-11)10(8)7-13(12)16/h6-7,9,11,14-16H,1-5H2/t9-,11-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum


J Med Chem 33: 1756-64 (1990)


Article DOI: 10.1021/jm00168a034
BindingDB Entry DOI: 10.7270/Q23X877X
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011256
PNG
((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 774n/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat


J Med Chem 31: 1130-40 (1988)


Article DOI: 10.1021/jm00401a012
BindingDB Entry DOI: 10.7270/Q23J3DJB
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/s2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452344
PNG
(CHEMBL2114055)
Show SMILES Oc1cccc2[C@H]3CCCN[C@@H]3CCc12
Show InChI InChI=1/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10-,12-/s2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.55E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452347
PNG
(CHEMBL306162)
Show SMILES CCCN1CCC[C@@H]2[C@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452347
PNG
(CHEMBL306162)
Show SMILES CCCN1CCC[C@@H]2[C@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 197n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452344
PNG
(CHEMBL2114055)
Show SMILES Oc1cccc2[C@H]3CCCN[C@@H]3CCc12
Show InChI InChI=1/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10-,12-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.37E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair