BindingDB logo
myBDB logout

2 similar compounds to monomer 50090256

Compile data set for download or QSAR
Wt: 500.6
BDBM50010962
Wt: 395.4
BDBM50090255
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010962,50090255   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))
BDBM50090255
PNG
(CHEMBL3581675)
Show SMILES CC\C(=C(\c1ccc(\C=C\C(O)=O)nc1)c1ccc2[nH]ncc2c1)c1ccccc1
Show InChI InChI=1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,23,25-27H,2-16H2,1H3/t17-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 110n/an/an/an/a



Seragon Pharmaceuticals

Curated by ChEMBL


Assay Description
Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assay


J Med Chem 58: 4888-904 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00054
BindingDB Entry DOI: 10.7270/Q29W0H7Q
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50010962
PNG
(CHEMBL3265160)
Show SMILES CN(C)CCN(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1ccccc1
Show InChI InChI=1S/C26H36N4O4S/c1-29(2)16-17-30(23(32)12-19-34-18-11-20-6-4-3-5-7-20)15-14-27-13-10-21-8-9-22(31)24-25(21)35-26(33)28-24/h3-9,27,31H,10-19H2,1-2H3,(H,28,33)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.30n/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...


ACS Med Chem Lett 5: 416-21 (2014)


Article DOI: 10.1021/ml4005232
BindingDB Entry DOI: 10.7270/Q2ZC84D5
More data for this
Ligand-Target Pair