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21 similar compounds to monomer 50005232

Compile data set for download or QSAR
Wt: 545.8
BDBM50011084
Wt: 503.7
BDBM50011085
Wt: 559.8
BDBM50011120
Wt: 517.7
BDBM50011081
Wt: 620.8
BDBM50020321
Wt: 592.8
BDBM50020325
Wt: 634.9
BDBM50020328
Wt: 602.8
BDBM50284388
Wt: 590.8
BDBM50284394
Wt: 616.8
BDBM50284395
Wt: 631.8
BDBM50284397
Wt: 618.8
BDBM50284400
Wt: 604.8
BDBM50284409
Wt: 618.8
BDBM50284414
Wt: 616.8
BDBM50284416
Displayed 1 to 15 (of 21 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50011084,50011085,50011120,50011081,50020321,50020325,50020328,50284388,50284394,50284395,50284397,50284400,50284409,50284414,50284416   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284388
PNG
(2-{[Acetyl-(1-hexadecylcarbamoyloxymethyl-cyclopen...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCCC1
Show InChI InChI=1S/C35H59N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-21-26-36-33(40)42-29-35(24-19-20-25-35)30-43-34(41)38(31(3)39)28-32-23-18-22-27-37(32)5-2/h18,22-23,27H,4-17,19-21,24-26,28-30H2,1-3H3/p+1
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1.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284416
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-cyclobut...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1
Show InChI InChI=1S/C36H61N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-37-35(41)43-29-32-26-33(27-32)30-44-36(42)39(31(3)40)28-34-23-20-22-25-38(34)5-2/h20,22-23,25,32-33H,4-19,21,24,26-30H2,1-3H3/p+1/t32-,33-
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4.30n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranes


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284395
PNG
(2-{[Acetyl-(1-octadecylcarbamoyloxymethyl-cyclobut...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCC1
Show InChI InChI=1S/C36H61N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-27-37-34(41)43-30-36(25-23-26-36)31-44-35(42)39(32(3)40)29-33-24-20-22-28-38(33)5-2/h20,22,24,28H,4-19,21,23,25-27,29-31H2,1-3H3/p+1
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6.60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284414
PNG
(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-34(40)42-28-32-26-33(44-32)29-43-35(41)38(30(3)39)27-31-23-20-22-25-37(31)5-2/h20,22-23,25,32-33H,4-19,21,24,26-29H2,1-3H3/p+1/t32-,33+/m1/s1
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9.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranes


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284409
PNG
(2-{[Acetyl-(2,2-dimethyl-3-octadecylcarbamoyloxy-p...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(C)(C)COC(=O)N(Cc1cccc[n+]1CC)C(C)=O
Show InChI InChI=1S/C35H61N3O5/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26-36-33(40)42-29-35(4,5)30-43-34(41)38(31(3)39)28-32-25-22-24-27-37(32)7-2/h22,24-25,27H,6-21,23,26,28-30H2,1-5H3/p+1
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13n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284414
PNG
(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-34(40)42-28-32-26-33(44-32)29-43-35(41)38(30(3)39)27-31-23-20-22-25-37(31)5-2/h20,22-23,25,32-33H,4-19,21,24,26-29H2,1-3H3/p+1/t32-,33+/m1/s1
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranes


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284400
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-33(40)43-29-35(27-42-28-35)30-44-34(41)38(31(3)39)26-32-23-20-22-25-37(32)5-2/h20,22-23,25H,4-19,21,24,26-30H2,1-3H3/p+1
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20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284400
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-33(40)43-29-35(27-42-28-35)30-44-34(41)38(31(3)39)26-32-23-20-22-25-37(32)5-2/h20,22-23,25H,4-19,21,24,26-30H2,1-3H3/p+1
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23n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284394
PNG
(2-{[Acetyl-(3-hexadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C33H55N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-19-22-34-31(38)41-27-33(25-40-26-33)28-42-32(39)36(29(3)37)24-30-21-18-20-23-35(30)5-2/h18,20-21,23H,4-17,19,22,24-28H2,1-3H3/p+1
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95n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284397
PNG
(2-{[Acetyl-(1-acetyl-3-hexadecylcarbamoyloxymethyl...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CN(C1)C(C)=O
Show InChI InChI=1S/C35H58N4O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-20-23-36-33(42)44-28-35(26-38(27-35)30(3)40)29-45-34(43)39(31(4)41)25-32-22-19-21-24-37(32)6-2/h19,21-22,24H,5-18,20,23,25-29H2,1-4H3/p+1
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278n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50011084
PNG
(2-{[Acetyl-(5-heptadecyl-tetrahydro-furan-2-ylmeth...)
Show SMILES CCCCCCCCCCCCCCCCCC1CCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C33H57N2O4/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-31-24-25-32(39-31)28-38-33(37)35(29(3)36)27-30-22-20-21-26-34(30)5-2/h20-22,26,31-32H,4-19,23-25,27-28H2,1-3H3/q+1
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n/an/a 71n/an/an/an/an/an/a



J. Uriach & Cía.S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity expressed as the concentration required to inhibit platelet-activating factor (PAF) induced maximum aggregation by 50%


J Med Chem 34: 373-86 (1991)


Article DOI: 10.1021/jm00105a058
BindingDB Entry DOI: 10.7270/Q2DF6Q51
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50011120
PNG
(2-{[Acetyl-(4-octadecyl-tetrahydro-furan-2-ylmetho...)
Show SMILES CCCCCCCCCCCCCCCCCCC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1
Show InChI InChI=1S/C34H59N2O4/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23-31-26-33(39-28-31)29-40-34(38)36(30(3)37)27-32-24-21-22-25-35(32)5-2/h21-22,24-25,31,33H,4-20,23,26-29H2,1-3H3/q+1
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n/an/a 470n/an/an/an/an/an/a



J. Uriach & Cía.S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity expressed as the concentration required to inhibit platelet-activating factor (PAF) induced maximum aggregation by 50%


J Med Chem 34: 373-86 (1991)


Article DOI: 10.1021/jm00105a058
BindingDB Entry DOI: 10.7270/Q2DF6Q51
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50011085
PNG
(2-{[Acetyl-(4-tetradecyl-tetrahydro-furan-2-ylmeth...)
Show SMILES CCCCCCCCCCCCCCC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1
Show InChI InChI=1S/C30H51N2O4/c1-4-6-7-8-9-10-11-12-13-14-15-16-19-27-22-29(35-24-27)25-36-30(34)32(26(3)33)23-28-20-17-18-21-31(28)5-2/h17-18,20-21,27,29H,4-16,19,22-25H2,1-3H3/q+1
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n/an/a 140n/an/an/an/an/an/a



J. Uriach & Cía.S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity expressed as the concentration required to inhibit platelet-activating factor (PAF) induced maximum aggregation by 50%


J Med Chem 34: 373-86 (1991)


Article DOI: 10.1021/jm00105a058
BindingDB Entry DOI: 10.7270/Q2DF6Q51
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50011081
PNG
(2-{[Acetyl-(5-pentadecyl-tetrahydro-furan-2-ylmeth...)
Show SMILES CCCCCCCCCCCCCCCC1CCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C31H53N2O4/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-21-29-22-23-30(37-29)26-36-31(35)33(27(3)34)25-28-20-18-19-24-32(28)5-2/h18-20,24,29-30H,4-17,21-23,25-26H2,1-3H3/q+1
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n/an/a 80n/an/an/an/an/an/a



J. Uriach & Cía.S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity expressed as the concentration required to inhibit platelet-activating factor (PAF) induced maximum aggregation by 50%


J Med Chem 34: 373-86 (1991)


Article DOI: 10.1021/jm00105a058
BindingDB Entry DOI: 10.7270/Q2DF6Q51
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50020325
PNG
(2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1C)C(C)=O)OC
Show InChI InChI=1S/C33H57N3O6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-34-32(38)41-27-31(40-4)28-42-33(39)36(29(2)37)26-30-23-20-22-25-35(30)3/h20,22-23,25,31H,5-19,21,24,26-28H2,1-4H3/p+1
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n/an/a 200n/an/an/an/an/an/a



Takeda Chemical Industries Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)


J Med Chem 32: 56-64 (1989)


Article DOI: 10.1021/jm00121a012
BindingDB Entry DOI: 10.7270/Q2ZP46QM
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50020321
PNG
(2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CCC)C(C)=O)OC
Show InChI InChI=1S/C35H61N3O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25-36-34(40)43-29-33(42-4)30-44-35(41)38(31(3)39)28-32-24-21-23-27-37(32)26-6-2/h21,23-24,27,33H,5-20,22,25-26,28-30H2,1-4H3/p+1
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n/an/a 94n/an/an/an/an/an/a



Takeda Chemical Industries Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)


J Med Chem 32: 56-64 (1989)


Article DOI: 10.1021/jm00121a012
BindingDB Entry DOI: 10.7270/Q2ZP46QM
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284414
PNG
(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-34(40)42-28-32-26-33(44-32)29-43-35(41)38(30(3)39)27-31-23-20-22-25-37(31)5-2/h20,22-23,25,32-33H,4-19,21,24,26-29H2,1-3H3/p+1/t32-,33+/m1/s1
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n/an/a 101n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284414
PNG
(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-34(40)42-28-32-26-33(44-32)29-43-35(41)38(30(3)39)27-31-23-20-22-25-37(31)5-2/h20,22-23,25,32-33H,4-19,21,24,26-29H2,1-3H3/p+1/t32-,33+/m1/s1
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n/an/a 97n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284416
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-cyclobut...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H]1C[C@H](COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1
Show InChI InChI=1S/C36H61N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-37-35(41)43-29-32-26-33(27-32)30-44-36(42)39(31(3)40)28-34-23-20-22-25-38(34)5-2/h20,22-23,25,32-33H,4-19,21,24,26-30H2,1-3H3/p+1/t32-,33-
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n/an/a 56n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets


Bioorg Med Chem Lett 5: 1097-1102 (1995)


Article DOI: 10.1016/0960-894X(95)00174-R
BindingDB Entry DOI: 10.7270/Q2NZ87KQ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284409
PNG
(2-{[Acetyl-(2,2-dimethyl-3-octadecylcarbamoyloxy-p...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(C)(C)COC(=O)N(Cc1cccc[n+]1CC)C(C)=O
Show InChI InChI=1S/C35H61N3O5/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26-36-33(40)42-29-35(4,5)30-43-34(41)38(31(3)39)28-32-25-22-24-27-37(32)7-2/h22,24-25,27H,6-21,23,26,28-30H2,1-5H3/p+1
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n/an/a 394n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284394
PNG
(2-{[Acetyl-(3-hexadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C33H55N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-19-22-34-31(38)41-27-33(25-40-26-33)28-42-32(39)36(29(3)37)24-30-21-18-20-23-35(30)5-2/h18,20-21,23H,4-17,19,22,24-28H2,1-3H3/p+1
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n/an/a 93n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284400
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-33(40)43-29-35(27-42-28-35)30-44-34(41)38(31(3)39)26-32-23-20-22-25-37(32)5-2/h20,22-23,25H,4-19,21,24,26-30H2,1-3H3/p+1
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n/an/a 123n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284397
PNG
(2-{[Acetyl-(1-acetyl-3-hexadecylcarbamoyloxymethyl...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CN(C1)C(C)=O
Show InChI InChI=1S/C35H58N4O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-20-23-36-33(42)44-28-35(26-38(27-35)30(3)40)29-45-34(43)39(31(4)41)25-32-22-19-21-24-37(32)6-2/h19,21-22,24H,5-18,20,23,25-29H2,1-4H3/p+1
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n/an/a 188n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284395
PNG
(2-{[Acetyl-(1-octadecylcarbamoyloxymethyl-cyclobut...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCC1
Show InChI InChI=1S/C36H61N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-27-37-34(41)43-30-36(25-23-26-36)31-44-35(42)39(32(3)40)29-33-24-20-22-28-38(33)5-2/h20,22,24,28H,4-19,21,23,25-27,29-31H2,1-3H3/p+1
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n/an/a 118n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50020328
PNG
(2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CCCC)C(C)=O)OC
Show InChI InChI=1S/C36H63N3O6/c1-5-7-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26-37-35(41)44-30-34(43-4)31-45-36(42)39(32(3)40)29-33-25-22-24-28-38(33)27-8-6-2/h22,24-25,28,34H,5-21,23,26-27,29-31H2,1-4H3/p+1
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n/an/a 110n/an/an/an/an/an/a



Takeda Chemical Industries Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)


J Med Chem 32: 56-64 (1989)


Article DOI: 10.1021/jm00121a012
BindingDB Entry DOI: 10.7270/Q2ZP46QM
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284400
PNG
(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)COC1
Show InChI InChI=1S/C35H59N3O6/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-36-33(40)43-29-35(27-42-28-35)30-44-34(41)38(31(3)39)26-32-23-20-22-25-37(32)5-2/h20,22-23,25H,4-19,21,24,26-30H2,1-3H3/p+1
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n/an/a 158n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284388
PNG
(2-{[Acetyl-(1-hexadecylcarbamoyloxymethyl-cyclopen...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCCC1
Show InChI InChI=1S/C35H59N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-21-26-36-33(40)42-29-35(24-19-20-25-35)30-43-34(41)38(31(3)39)28-32-23-18-22-27-37(32)5-2/h18,22-23,27H,4-17,19-21,24-26,28-30H2,1-3H3/p+1
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n/an/a 350n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair