BindingDB logo
myBDB logout

6 similar compounds to monomer 50011431

Compile data set for download or QSAR
Wt: 489.4
BDBM50011448
Wt: 416.4
BDBM50011454
Wt: 326.3
BDBM50011456
Wt: 367.3
BDBM50011460
Wt: 295.2
BDBM50011416
Wt: 355.2
BDBM50011419
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50011448,50011454,50011456,50011460,50011416,50011419   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011416
PNG
(2-(4-Amino-phenyl)-4-oxo-4H-chromene-3-carboxylic ...)
Show SMILES COC(=O)c1c(oc2ccccc2c1=O)-c1ccc(N)cc1
Show InChI InChI=1S/C17H13NO4/c1-21-17(20)14-15(19)12-4-2-3-5-13(12)22-16(14)10-6-8-11(18)9-7-10/h2-9H,18H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.10E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011419
PNG
(6-Methoxy-2-(4-nitro-phenyl)-4-oxo-4H-chromene-3-c...)
Show SMILES COC(=O)c1c(oc2ccc(OC)cc2c1=O)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H13NO7/c1-24-12-7-8-14-13(9-12)16(20)15(18(21)25-2)17(26-14)10-3-5-11(6-4-10)19(22)23/h3-9H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011460
PNG
(2-(4-Acetylamino-phenyl)-7-methoxy-4-oxo-4H-chrome...)
Show SMILES COC(=O)c1c(oc2cc(OC)ccc2c1=O)-c1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C20H17NO6/c1-11(22)21-13-6-4-12(5-7-13)19-17(20(24)26-3)18(23)15-9-8-14(25-2)10-16(15)27-19/h4-10H,1-3H3,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011448
PNG
(4-Oxo-2-[4-(3,4,5-trimethoxy-benzoylamino)-phenyl]...)
Show SMILES COC(=O)c1c(oc2ccccc2c1=O)-c1ccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1
Show InChI InChI=1S/C27H23NO8/c1-32-20-13-16(14-21(33-2)25(20)34-3)26(30)28-17-11-9-15(10-12-17)24-22(27(31)35-4)23(29)18-7-5-6-8-19(18)36-24/h5-14H,1-4H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011456
PNG
(2-(4-Hydroxy-phenyl)-6-methoxy-4-oxo-4H-chromene-3...)
Show SMILES COC(=O)c1c(oc2ccc(OC)cc2c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C18H14O6/c1-22-12-7-8-14-13(9-12)16(20)15(18(21)23-2)17(24-14)10-3-5-11(19)6-4-10/h3-9,19H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50011454
PNG
(2-(4-Benzyloxy-phenyl)-6-methoxy-4-oxo-4H-chromene...)
Show SMILES COC(=O)c1c(oc2ccc(OC)cc2c1=O)-c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C25H20O6/c1-28-19-12-13-21-20(14-19)23(26)22(25(27)29-2)24(31-21)17-8-10-18(11-9-17)30-15-16-6-4-3-5-7-16/h3-14H,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair