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26 similar compounds to monomer 50011481

Compile data set for download or QSAR
Wt: 319.4
BDBM50388400
Wt: 319.4
BDBM50388401
Wt: 319.4
BDBM50388402
Wt: 305.3
BDBM50388403
Wt: 333.4
BDBM50388404
Wt: 361.4
BDBM50388405
Wt: 339.8
BDBM50388415
Wt: 319.4
BDBM50388421
Wt: 319.4
BDBM50388422
Wt: 385.4
BDBM50011483
Wt: 385.4
BDBM50011485
Wt: 381.4
BDBM50011487
Wt: 397.4
BDBM50011489
Wt: 439.5
BDBM50011492
Wt: 399.4
BDBM50011494
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50388400,50388401,50388402,50388403,50388404,50388405,50388415,50388421,50388422,50011483,50011485,50011487,50011489,50011492,50011494   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011494
PNG
(CHEMBL3261904)
Show SMILES CCN(Cc1ccc(C)cc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1
Show InChI InChI=1S/C25H22FN3O/c1-3-29(16-18-14-12-17(2)13-15-18)25(30)24-27-22-11-7-5-9-20(22)23(28-24)19-8-4-6-10-21(19)26/h4-15H,3,16H2,1-2H3
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0.600n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011483
PNG
(CHEMBL3261893)
Show SMILES CCN(Cc1ccccc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1
Show InChI InChI=1S/C24H20FN3O/c1-2-28(16-17-10-4-3-5-11-17)24(29)23-26-21-15-9-7-13-19(21)22(27-23)18-12-6-8-14-20(18)25/h3-15H,2,16H2,1H3
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0.888n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011487
PNG
(CHEMBL3261897)
Show SMILES CCN(Cc1ccccc1)C(=O)c1nc(-c2ccc(C)cc2)c2ccccc2n1
Show InChI InChI=1S/C25H23N3O/c1-3-28(17-19-9-5-4-6-10-19)25(29)24-26-22-12-8-7-11-21(22)23(27-24)20-15-13-18(2)14-16-20/h4-16H,3,17H2,1-2H3
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1.5n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011485
PNG
(CHEMBL3261895)
Show SMILES CCN(Cc1ccccc1)C(=O)c1nc(-c2ccc(F)cc2)c2ccccc2n1
Show InChI InChI=1S/C24H20FN3O/c1-2-28(16-17-8-4-3-5-9-17)24(29)23-26-21-11-7-6-10-20(21)22(27-23)18-12-14-19(25)15-13-18/h3-15H,2,16H2,1H3
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1.70n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011489
PNG
(CHEMBL3261899)
Show SMILES CCN(Cc1ccc(OC)cc1)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C25H23N3O2/c1-3-28(17-18-13-15-20(30-2)16-14-18)25(29)24-26-22-12-8-7-11-21(22)23(27-24)19-9-5-4-6-10-19/h4-16H,3,17H2,1-2H3
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2.80n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388401
PNG
(CHEMBL2058819)
Show SMILES CCC(C)N(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1/C20H21N3O/c1-4-14(2)23(3)20(24)19-21-17-13-9-8-12-16(17)18(22-19)15-10-6-5-7-11-15/h5-14H,4H2,1-3H3
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3n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388405
PNG
(CHEMBL2058823)
Show SMILES CCCCN(CCCC)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C23H27N3O/c1-3-5-16-26(17-6-4-2)23(27)22-24-20-15-11-10-14-19(20)21(25-22)18-12-8-7-9-13-18/h7-15H,3-6,16-17H2,1-2H3
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3.30n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50011492
PNG
(CHEMBL3261902)
Show SMILES CCOC(=O)c1ccc(CN(CC)C(=O)c2nc(-c3ccccc3)c3ccccc3n2)cc1
Show InChI InChI=1S/C27H25N3O3/c1-3-30(18-19-14-16-21(17-15-19)27(32)33-4-2)26(31)25-28-23-13-9-8-12-22(23)24(29-25)20-10-6-5-7-11-20/h5-17H,3-4,18H2,1-2H3
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3.70n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes


J Med Chem 57: 2413-28 (2014)


Article DOI: 10.1021/jm401721h
BindingDB Entry DOI: 10.7270/Q2416ZKP
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388421
PNG
(CHEMBL2059059)
Show SMILES CC[C@H](C)N(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1/C20H21N3O/c1-4-14(2)23(3)20(24)19-21-17-13-9-8-12-16(17)18(22-19)15-10-6-5-7-11-15/h5-14H,4H2,1-3H3/t14-/s2
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6.09n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388422
PNG
(CHEMBL2059060)
Show SMILES CC[C@@H](C)N(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1/C20H21N3O/c1-4-14(2)23(3)20(24)19-21-17-13-9-8-12-16(17)18(22-19)15-10-6-5-7-11-15/h5-14H,4H2,1-3H3/t14-/s2
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6.41n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388404
PNG
(CHEMBL2058822)
Show SMILES CCCN(CCC)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C21H23N3O/c1-3-14-24(15-4-2)21(25)20-22-18-13-9-8-12-17(18)19(23-20)16-10-6-5-7-11-16/h5-13H,3-4,14-15H2,1-2H3
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36.8n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388400
PNG
(CHEMBL2058818)
Show SMILES CCCCN(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C20H21N3O/c1-3-4-14-23(2)20(24)19-21-17-13-9-8-12-16(17)18(22-19)15-10-6-5-7-11-15/h5-13H,3-4,14H2,1-2H3
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46n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388415
PNG
(CHEMBL2059050)
Show SMILES CC(C)N(C)C(=O)c1nc(-c2ccc(Cl)cc2)c2ccccc2n1
Show InChI InChI=1S/C19H18ClN3O/c1-12(2)23(3)19(24)18-21-16-7-5-4-6-15(16)17(22-18)13-8-10-14(20)11-9-13/h4-12H,1-3H3
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50.4n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388402
PNG
(CHEMBL2058820)
Show SMILES CC(C)CN(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C20H21N3O/c1-14(2)13-23(3)20(24)19-21-17-12-8-7-11-16(17)18(22-19)15-9-5-4-6-10-15/h4-12,14H,13H2,1-3H3
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66.5n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50388403
PNG
(CHEMBL2058821)
Show SMILES CC(C)N(C)C(=O)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C19H19N3O/c1-13(2)22(3)19(23)18-20-16-12-8-7-11-15(16)17(21-18)14-9-5-4-6-10-14/h4-13H,1-3H3
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70.3n/an/an/an/an/an/an/an/a



Universit£ di Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat kidney mitochondrial membranes by competitive binding assay


J Med Chem 55: 4506-10 (2012)


Article DOI: 10.1021/jm201703k
BindingDB Entry DOI: 10.7270/Q2TB1806
More data for this
Ligand-Target Pair