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26 similar compounds to monomer 50017130

Wt: 720.8
BDBM50014096
Wt: 683.8
BDBM50031425
Wt: 1298.5
BDBM50074645
Wt: 1039.2
BDBM50117488
Wt: 570.6
BDBM50122068
Wt: 646.7
BDBM50122069
Wt: 722.8
BDBM50122070
Wt: 636.7
BDBM50122071
Wt: 722.8
BDBM50122072
Wt: 696.7
BDBM50122073
Wt: 647.7
BDBM50122075
Wt: 696.7
BDBM50122076
Wt: 722.8
BDBM50122058
Wt: 646.7
BDBM50122061
Wt: 722.8
BDBM50122063
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 50014096,50031425,50074645,50117488,50122068,50122069,50122070,50122071,50122072,50122073,50122075,50122076,50122058,50122061,50122063   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Renin


(Homo sapiens (human))
BDBM50014096
PNG
(1-Acetyl-pyrrolidine-2-carboxylic acid {1-[1-{1-[(...)
Show SMILES CC(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CNC(Cc1ccccc1)C(N)=O)Cc1ccccc1
Show InChI InChI=1S/C40H48N8O5/c1-27(49)48-19-11-18-36(48)40(53)47-34(22-30-16-9-4-10-17-30)39(52)46-35(23-31-24-42-26-44-31)38(51)45-32(20-28-12-5-2-6-13-28)25-43-33(37(41)50)21-29-14-7-3-8-15-29/h2-10,12-17,24,26,32-36,43H,11,18-23,25H2,1H3,(H2,41,50)(H,42,44)(H,45,51)(H,46,52)(H,47,53)
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n/an/an/a 29n/an/an/an/an/a



Upjohn Company

Curated by ChEMBL


Assay Description
Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assay


Citation and Details
More data for this
Ligand-Target Pair
Cyclin-A2


(Homo sapiens (human))
BDBM50117488
PNG
(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C48H82N18O8/c1-6-28(4)38(46(74)64-36(39(51)67)23-30-14-8-7-9-15-30)66-45(73)37(22-27(2)3)65-44(72)35(18-13-21-58-48(54)55)63-43(71)34(17-12-20-57-47(52)53)62-42(70)33(16-10-11-19-49)61-40(68)29(5)60-41(69)32(50)24-31-25-56-26-59-31/h7-9,14-15,25-29,32-38H,6,10-13,16-24,49-50H2,1-5H3,(H2,51,67)(H,56,59)(H,60,69)(H,61,68)(H,62,70)(H,63,71)(H,64,74)(H,65,72)(H,66,73)(H4,52,53,57)(H4,54,55,58)/t28-,29-,32-,33-,34-,35-,36-,37-,38-/m0/s1
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n/an/a 50n/an/an/an/an/an/a



Georgetown University

Curated by ChEMBL


Assay Description
Binding affinity to Cyclin A by competitive binding assay


AAPS J 8: 204-21 (2006)

More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50117488
PNG
(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C48H82N18O8/c1-6-28(4)38(46(74)64-36(39(51)67)23-30-14-8-7-9-15-30)66-45(73)37(22-27(2)3)65-44(72)35(18-13-21-58-48(54)55)63-43(71)34(17-12-20-57-47(52)53)62-42(70)33(16-10-11-19-49)61-40(68)29(5)60-41(69)32(50)24-31-25-56-26-59-31/h7-9,14-15,25-29,32-38H,6,10-13,16-24,49-50H2,1-5H3,(H2,51,67)(H,56,59)(H,60,69)(H,61,68)(H,62,70)(H,63,71)(H,64,74)(H,65,72)(H,66,73)(H4,52,53,57)(H4,54,55,58)/t28-,29-,32-,33-,34-,35-,36-,37-,38-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



Georgetown University

Curated by ChEMBL


Assay Description
Inhibition of CDK2/cyclin A


AAPS J 8: 204-21 (2006)

More data for this
Ligand-Target Pair
Myosin light chain kinase, smooth muscle


(Gallus gallus (chicken))
BDBM50074645
PNG
(CHEMBL265875 | R-K-K-Y-K-H-R-R-K-NH2)
Show SMILES NCCCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C57H103N25O10/c58-23-5-1-13-38(46(63)84)75-48(86)42(17-10-28-72-56(66)67)78-50(88)43(18-11-29-73-57(68)69)80-54(92)45(31-35-32-70-33-74-35)82-52(90)41(16-4-8-26-61)79-53(91)44(30-34-19-21-36(83)22-20-34)81-51(89)40(15-3-7-25-60)77-49(87)39(14-2-6-24-59)76-47(85)37(62)12-9-27-71-55(64)65/h19-22,32-33,37-45,83H,1-18,23-31,58-62H2,(H2,63,84)(H,70,74)(H,75,86)(H,76,85)(H,77,87)(H,78,88)(H,79,91)(H,80,92)(H,81,89)(H,82,90)(H4,64,65,71)(H4,66,67,72)(H4,68,69,73)/t37-,38-,39-,40-,41-,42-,43-,44-,45-/m0/s1
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n/an/a 290n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)


J Med Chem 42: 910-9 (1999)

More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122058
PNG
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1
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n/an/an/an/a 1.60E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122061
PNG
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1
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n/an/an/an/a 2.70E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122063
PNG
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1
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n/an/an/an/a 51.9n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122058
PNG
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1
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n/an/an/an/a 680n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122068
PNG
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)
Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O
Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1
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n/an/an/an/a 3.84E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122061
PNG
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1
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n/an/an/an/a 890n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122069
PNG
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122063
PNG
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1
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n/an/an/an/a 2.70E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122070
PNG
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1
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n/an/an/an/a 1.50E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122070
PNG
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1
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n/an/an/an/a 150n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
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n/an/an/an/a 2.76E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122068
PNG
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)
Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O
Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122069
PNG
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122068
PNG
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)
Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O
Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1
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n/an/an/an/a 4.40E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122070
PNG
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1
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n/an/an/an/a 1.62E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122072
PNG
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1
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n/an/an/an/a 2.30E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122061
PNG
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1
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n/an/an/an/a 7.80E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122070
PNG
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1
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n/an/an/an/a 310n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
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n/an/an/an/a 3.60E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122058
PNG
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1
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n/an/an/an/a 7.44E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122073
PNG
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1
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n/an/an/an/a 730n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122072
PNG
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1
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n/an/an/an/a 7.10E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122073
PNG
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1
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n/an/an/an/a 3.50E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122063
PNG
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1
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n/an/an/an/a 1.34E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122075
PNG
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O
Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1
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n/an/an/an/a 1.45E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122069
PNG
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1
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n/an/an/an/a 1.50E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122063
PNG
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1
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n/an/an/an/a 100n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122076
PNG
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1
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n/an/an/an/a 12.1n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122075
PNG
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O
Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122061
PNG
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1
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n/an/an/an/a 530n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122073
PNG
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1
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n/an/an/an/a 260n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122072
PNG
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1
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n/an/an/an/a 5.33E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122068
PNG
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)
Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O
Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1
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n/an/an/an/a 4.37E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122075
PNG
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O
Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1
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n/an/an/an/a 3.00E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122072
PNG
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1
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n/an/an/an/a 1.16E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122069
PNG
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1
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n/an/an/an/a 470n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122075
PNG
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O
Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1
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n/an/an/an/a 2.24E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122076
PNG
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1
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n/an/an/an/a 127n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122058
PNG
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1
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n/an/an/an/a 7.80E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122073
PNG
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1
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n/an/an/an/a 33.1n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122076
PNG
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1
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n/an/an/an/a 1.62E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
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n/an/an/an/a 3.80E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


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Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50122076
PNG
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O
Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1
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n/an/an/an/a 46.2n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


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More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50117488
PNG
(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C48H82N18O8/c1-6-28(4)38(46(74)64-36(39(51)67)23-30-14-8-7-9-15-30)66-45(73)37(22-27(2)3)65-44(72)35(18-13-21-58-48(54)55)63-43(71)34(17-12-20-57-47(52)53)62-42(70)33(16-10-11-19-49)61-40(68)29(5)60-41(69)32(50)24-31-25-56-26-59-31/h7-9,14-15,25-29,32-38H,6,10-13,16-24,49-50H2,1-5H3,(H2,51,67)(H,56,59)(H,60,69)(H,61,68)(H,62,70)(H,63,71)(H,64,74)(H,65,72)(H,66,73)(H4,52,53,57)(H4,54,55,58)/t28-,29-,32-,33-,34-,35-,36-,37-,38-/m0/s1
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n/an/a 39n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
In vitro inhibition of CDK2-cyclin A kinase activity on retinoblastoma protein


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Ligand-Target Pair
Proteinase-activated receptor 1 (PAR1)


(Homo sapiens (Human))
BDBM50031425
PNG
((S)-2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-pro...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C33H53N11O5/c1-19(2)13-25(30(47)41-24(28(35)45)11-8-12-39-33(36)37)43-31(48)26(14-20(3)4)44-32(49)27(15-21-9-6-5-7-10-21)42-29(46)23(34)16-22-17-38-18-40-22/h5-7,9-10,17-20,23-27H,8,11-16,34H2,1-4H3,(H2,35,45)(H,38,40)(H,41,47)(H,42,46)(H,43,48)(H,44,49)(H4,36,37,39)/t23-,24-,25-,26-,27-/m0/s1
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n/an/an/an/a 3.10E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Evaluated for the activation of human thrombin receptor measured by platelet aggregation


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Ligand-Target Pair