BindingDB logo
myBDB logout

2 similar compounds to monomer 50014775

Compile data set for download or QSAR
Wt: 380.2
BDBM50014750
Wt: 369.2
BDBM50014763

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014750,50014763   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014763
PNG
(4-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...)
Show SMILES Clc1ccc(cc1)C(c1cn[nH]c1)(c1ccc(Cl)cc1)n1ccnc1
Show InChI InChI=1S/C19H14Cl2N4/c20-17-5-1-14(2-6-17)19(16-11-23-24-12-16,25-10-9-22-13-25)15-3-7-18(21)8-4-15/h1-13H,(H,23,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 11n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014750
PNG
(3-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-pyr...)
Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)(c1cccnc1)n1ccnc1
Show InChI InChI=1S/C21H15Cl2N3/c22-19-7-3-16(4-8-19)21(26-13-12-25-15-26,18-2-1-11-24-14-18)17-5-9-20(23)10-6-17/h1-15H
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 50n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair