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2 similar compounds to monomer 50014794

Compile data set for download or QSAR
Wt: 328.2
BDBM50014751
Wt: 348.6
BDBM50014753

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014751,50014753   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014753
PNG
(3-[Chloro-bis-(4-chloro-phenyl)-methyl]-pyridine :...)
Show SMILES Clc1ccc(cc1)C(Cl)(c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C18H12Cl3N/c19-16-7-3-13(4-8-16)18(21,15-2-1-11-22-12-15)14-5-9-17(20)10-6-14/h1-12H
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 200n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014751
PNG
(3-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyridine | CHE...)
Show SMILES CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C19H15Cl2N/c1-19(16-3-2-12-22-13-16,14-4-8-17(20)9-5-14)15-6-10-18(21)11-7-15/h2-13H,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 145n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair