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| Wt: 406.4 BDBM50328425  | Wt: 505.5 BDBM50015488  |
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aurora kinase A (Homo sapiens (Human)) | BDBM50328425 (CHEMBL1257445 | N-(4-(6-(pyridin-3-yl)imidazo[1,2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human aurora A | Bioorg Med Chem Lett 20: 5988-93 (2010) Article DOI: 10.1016/j.bmcl.2010.08.091 BindingDB Entry DOI: 10.7270/Q2H995D7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM50015488 (CHEMBL3264994) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Inc Curated by ChEMBL | Assay Description Inhibition of full length Syk (unknown origin) using biotinylated peptide substrate | J Med Chem 57: 3856-73 (2014) Article DOI: 10.1021/jm500228a BindingDB Entry DOI: 10.7270/Q2B27WV1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
