Compounds in cluster

17 similar compounds to monomer 50027147

Wt: 422.4 BDBM50017474	Wt: 476.5 BDBM50021801	Wt: 422.4 BDBM50027344	Wt: 482.5 BDBM50027132	Wt: 436.5 BDBM50027480
Wt: 438.4 BDBM50027138	Wt: 422.4 BDBM50027141	Wt: 528.5 BDBM50027146	Wt: 436.5 BDBM50027148	Wt: 436.5 BDBM50027150
Wt: 472.5 BDBM50027152	Wt: 436.5 BDBM50027153	Wt: 436.5 BDBM50146426	Wt: 436.5 BDBM50146427	Wt: 436.5 BDBM50146428

Displayed 1 to 15 (of 17 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50017474,50021801,50027344,50027132,50027480,50027138,50027141,50027146,50027148,50027150,50027152,50027153,50146426,50146427,50146428
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027141 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of Angiotensin I converting enzyme				J Med Chem 32: 1378-92 (1989) Article DOI: 10.1021/jm00126a039 BindingDB Entry DOI: 10.7270/Q20G3KQ1
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of rabbit testis recombinant ACE C domain				Bioorg Med Chem Lett 16: 4612-5 (2006) Article DOI: 10.1016/j.bmcl.2006.06.003 BindingDB Entry DOI: 10.7270/Q2B56JC8
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of recombinant ACE N domain				Bioorg Med Chem Lett 16: 4612-5 (2006) Article DOI: 10.1016/j.bmcl.2006.06.003 BindingDB Entry DOI: 10.7270/Q2B56JC8
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50021801 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-octahyd...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.				J Med Chem 30: 992-8 (1987) Article DOI: 10.1021/jm00389a006 BindingDB Entry DOI: 10.7270/Q29C6Z02
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50027141 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.				J Med Chem 30: 992-8 (1987) Article DOI: 10.1021/jm00389a006 BindingDB Entry DOI: 10.7270/Q29C6Z02
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50146427 ((S)-1-((1S,5R)-5-Benzoylamino-2-methyl-4-oxo-6-phe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of ACE				J Med Chem 54: 2529-91 (2011) Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50146428 ((S)-1-((1R,5S)-5-Benzoylamino-2-methyl-4-oxo-6-phe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of ACE				J Med Chem 54: 2529-91 (2011) Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50017474 ((S,S)-1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of angiotensin I converting enzyme in silico				J Med Chem 40: 3161-72 (1997) Article DOI: 10.1021/jm970211n BindingDB Entry DOI: 10.7270/Q2MG7QPB
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin converting enzyme (ACE)				J Med Chem 36: 2390-403 (1993) Article DOI: 10.1021/jm00068a017 BindingDB Entry DOI: 10.7270/Q2Z320V9
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme				J Med Chem 28: 434-42 (1985) Article DOI: 10.1021/jm00382a008 BindingDB Entry DOI: 10.7270/Q2RV0PVJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of porcine plasma Angiotensin I converting enzyme by using fluorometric assay				J Med Chem 28: 1062-6 (1985) Article DOI: 10.1021/jm00146a014 BindingDB Entry DOI: 10.7270/Q2H996C6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027141 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against porcine plasma Angiotensin I converting enzyme				J Med Chem 28: 1067-71 (1985) Article DOI: 10.1021/jm00146a015 BindingDB Entry DOI: 10.7270/Q2CJ8FPX
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027480 (1-(6-Benzoylamino-5-oxo-7-phenyl-heptanoyl)-pyrrol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Angiotensin I converting enzyme				J Med Chem 25: 996-9 (1982) Article DOI: 10.1021/jm00350a023 BindingDB Entry DOI: 10.7270/Q2154G1D
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Angiotensin I converting enzyme				J Med Chem 25: 996-9 (1982) Article DOI: 10.1021/jm00350a023 BindingDB Entry DOI: 10.7270/Q2154G1D
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027132 (1-[5-Benzoylamino-6-(3,4-dimethoxy-phenyl)-4-oxo-h...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027344 ((S)-1-((S)-5-benzamido-4-oxo-6-phenylhexanoyl)pyrr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027153 (1-(6-Benzoylamino-5-oxo-7-phenyl-heptanoyl)-pyrrol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027152 (2-(5-Benzoylamino-4-oxo-6-phenyl-hexanoylamino)-3-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027138 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-4-hydro...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027148 (1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027150 (1-[5-(2-Methyl-benzoylamino)-4-oxo-6-phenyl-hexano...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50146426 ((S)-1-((1S,5S)-5-Benzoylamino-2-methyl-4-oxo-6-phe...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity of compound against angiotensin I converting enzyme was determined				Bioorg Med Chem Lett 14: 2853-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.042 BindingDB Entry DOI: 10.7270/Q2CJ8CX7
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
ACEI-ACE2 (Homo sapiens (Human))	BDBM50027146 (1-[5-Benzoylamino-6-(4-benzyloxy-phenyl)-4-oxo-hex...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%				J Med Chem 24: 964-9 (1982) Article DOI: 10.1021/jm00140a010 BindingDB Entry DOI: 10.7270/Q2959J4Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50146428 ((S)-1-((1R,5S)-5-Benzoylamino-2-methyl-4-oxo-6-phe...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity of compound against angiotensin I converting enzyme was determined				Bioorg Med Chem Lett 14: 2853-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.042 BindingDB Entry DOI: 10.7270/Q2CJ8CX7
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50146427 ((S)-1-((1S,5R)-5-Benzoylamino-2-methyl-4-oxo-6-phe...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity of compound against angiotensin I converting enzyme was determined				Bioorg Med Chem Lett 14: 2853-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.042 BindingDB Entry DOI: 10.7270/Q2CJ8CX7
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair