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6 similar compounds to monomer 50018685

Wt: 257.3
BDBM50018679
Wt: 271.3
BDBM50018680
Wt: 285.3
BDBM50018681
Wt: 283.3
BDBM50018682
Wt: 281.3
BDBM50018683
Wt: 282.3
BDBM50018684

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50018679,50018680,50018681,50018682,50018683,50018684   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018679
PNG
(CHEMBL3291292)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(C)c2n1
Show InChI InChI=1S/C14H19N5/c1-3-4-5-6-7-8-9-11-17-13(15)12-14(18-11)19(2)10-16-12/h10H,3-7H2,1-2H3,(H2,15,17,18)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018680
PNG
(CHEMBL3291293)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(CC)c2n1
Show InChI InChI=1S/C15H21N5/c1-3-5-6-7-8-9-10-12-18-14(16)13-15(19-12)20(4-2)11-17-13/h11H,3-8H2,1-2H3,(H2,16,18,19)
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n/an/a 6.70E+3n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018684
PNG
(CHEMBL3291297)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(CC#N)c2n1
Show InChI InChI=1S/C15H18N6/c1-2-3-4-5-6-7-8-12-19-14(17)13-15(20-12)21(10-9-16)11-18-13/h11H,2-6,10H2,1H3,(H2,17,19,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018682
PNG
(CHEMBL3291295)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(CC=C)c2n1
Show InChI InChI=1S/C16H21N5/c1-3-5-6-7-8-9-10-13-19-15(17)14-16(20-13)21(11-4-2)12-18-14/h4,12H,2-3,5-8,11H2,1H3,(H2,17,19,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018683
PNG
(CHEMBL3291296)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(CC#C)c2n1
Show InChI InChI=1S/C16H19N5/c1-3-5-6-7-8-9-10-13-19-15(17)14-16(20-13)21(11-4-2)12-18-14/h2,12H,3,5-8,11H2,1H3,(H2,17,19,20)
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n/an/a 200n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50018681
PNG
(CHEMBL3291294)
Show SMILES CCCCCCC#Cc1nc(N)c2ncn(CCC)c2n1
Show InChI InChI=1S/C16H23N5/c1-3-5-6-7-8-9-10-13-19-15(17)14-16(20-13)21(11-4-2)12-18-14/h12H,3-8,11H2,1-2H3,(H2,17,19,20)
PDB
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PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Yamasa Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodil...


Bioorg Med Chem 22: 3072-82 (2014)

More data for this
Ligand-Target Pair