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1 similar compounds to monomer 81811

Compile data set for download or QSAR
Wt: 227.3
BDBM50018736

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018736   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
adrenergic Alpha2


(BOVINE)
BDBM50018736
PNG
(1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4a-aza-benzo[a]f...)
Show SMILES C1CCN2CCc3c(oc4ccccc34)C2C1
Show InChI InChI=1S/C15H17NO/c1-2-7-14-11(5-1)12-8-10-16-9-4-3-6-13(16)15(12)17-14/h1-2,5,7,13H,3-4,6,8-10H2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranes


J Med Chem 31: 641-5 (1988)


Article DOI: 10.1021/jm00398a025
BindingDB Entry DOI: 10.7270/Q208649B
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(BOVINE)
BDBM50018736
PNG
(1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4a-aza-benzo[a]f...)
Show SMILES C1CCN2CCc3c(oc4ccccc34)C2C1
Show InChI InChI=1S/C15H17NO/c1-2-7-14-11(5-1)12-8-10-16-9-4-3-6-13(16)15(12)17-14/h1-2,5,7,13H,3-4,6,8-10H2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranes


J Med Chem 31: 641-5 (1988)


Article DOI: 10.1021/jm00398a025
BindingDB Entry DOI: 10.7270/Q208649B
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50018736
PNG
(1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4a-aza-benzo[a]f...)
Show SMILES C1CCN2CCc3c(oc4ccccc34)C2C1
Show InChI InChI=1S/C15H17NO/c1-2-7-14-11(5-1)12-8-10-16-9-4-3-6-13(16)15(12)17-14/h1-2,5,7,13H,3-4,6,8-10H2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptor


J Med Chem 31: 641-5 (1988)


Article DOI: 10.1021/jm00398a025
BindingDB Entry DOI: 10.7270/Q208649B
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50018736
PNG
(1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4a-aza-benzo[a]f...)
Show SMILES C1CCN2CCc3c(oc4ccccc34)C2C1
Show InChI InChI=1S/C15H17NO/c1-2-7-14-11(5-1)12-8-10-16-9-4-3-6-13(16)15(12)17-14/h1-2,5,7,13H,3-4,6,8-10H2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptor


J Med Chem 31: 641-5 (1988)


Article DOI: 10.1021/jm00398a025
BindingDB Entry DOI: 10.7270/Q208649B
More data for this
Ligand-Target Pair