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14 similar compounds to monomer 50184953

Wt: 371.3
BDBM50019251
Wt: 431.4
BDBM50019262
Wt: 380.3
BDBM50019269
Wt: 311.3
BDBM50019274
Wt: 405.4
BDBM50019188
Wt: 251.2
BDBM50019183
Purchase
Wt: 411.4
BDBM50019214
Wt: 397.4
BDBM50019221
Wt: 405.4
BDBM50019232
Wt: 308.3
BDBM50043532
Wt: 383.4
BDBM50061206
Wt: 335.3
BDBM50367630
Wt: 349.4
BDBM50367638
Wt: 402.4
BDBM50407252

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50019251,50019262,50019269,50019274,50019188,50019183,50019214,50019221,50019232,50043532,50061206,50367630,50367638,50407252   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin


(RAT)
BDBM50019274
PNG
(CCK antagonist synthetic 16 | CHEMBL72057 | N-[5-(...)
Show SMILES CC(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O
Show InChI InChI=1S/C17H14FN3O2/c1-10(22)19-16-17(23)20-14-9-5-3-7-12(14)15(21-16)11-6-2-4-8-13(11)18/h2-9,16H,1H3,(H,19,22)(H,20,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database




Proc Natl Acad Sci U S A 83: 4918-22 (1986)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50407252
PNG
(CHEMBL420722)
Show SMILES Fc1ccccc1C1=NC(NC(=O)CNc2ccccc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C23H19FN4O2/c24-18-12-6-4-10-16(18)21-17-11-5-7-13-19(17)26-23(30)22(28-21)27-20(29)14-25-15-8-2-1-3-9-15/h1-13,22,25H,14H2,(H,26,30)(H,27,29)
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n/an/a 89.1n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50061206
PNG
(CHEMBL124306 | N-((R)-1-Methyl-2-oxo-5-phenyl-2,3-...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H21N3O2/c1-27-20-15-9-8-14-19(20)22(18-12-6-3-7-13-18)26-23(24(27)29)25-21(28)16-17-10-4-2-5-11-17/h2-15,23H,16H2,1H3,(H,25,28)/t23-/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Half maximal inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cerebral cortex.


J Med Chem 40: 3865-8 (1998)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019183
PNG
(3-Amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin...)
Show SMILES NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C15H13N3O/c16-14-15(19)17-12-9-5-4-8-11(12)13(18-14)10-6-2-1-3-7-10/h1-9,14H,16H2,(H,17,19)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019188
PNG
(CHEMBL422951 | Naphthalene-2-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-14-17-8-4-5-11-19(17)16-20)29-24-26(31)27-22-13-7-6-12-21(22)23(28-24)18-9-2-1-3-10-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019232
PNG
(CHEMBL309017 | Naphthalene-1-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cccc2ccccc12
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-8-12-17-9-4-5-13-19(17)20)29-24-26(31)27-22-16-7-6-14-21(22)23(28-24)18-10-2-1-3-11-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019221
PNG
(CHEMBL308756 | N-(2-Oxo-5-phenyl-2,3-dihydro-1H-be...)
Show SMILES CCCc1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C25H23N3O2/c1-2-8-17-13-15-19(16-14-17)24(29)28-23-25(30)26-21-12-7-6-11-20(21)22(27-23)18-9-4-3-5-10-18/h3-7,9-16,23H,2,8H2,1H3,(H,26,30)(H,28,29)
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n/an/a 3.60E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50367630
PNG
(CHEMBL1907665)
Show SMILES CC(C)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O
Show InChI InChI=1S/C20H21N3O2/c1-13(2)19(24)22-18-20(25)23(3)16-12-8-7-11-15(16)17(21-18)14-9-5-4-6-10-14/h4-13,18H,1-3H3,(H,22,24)/t18-/m1/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-8 binding to cholecystokinin receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50367638
PNG
(CHEMBL1907660)
Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)C(C)(C)C)C1=O)c1ccccc1
Show InChI InChI=1S/C21H23N3O2/c1-21(2,3)20(26)23-18-19(25)24(4)16-13-9-8-12-15(16)17(22-18)14-10-6-5-7-11-14/h5-13,18H,1-4H3,(H,23,26)/t18-/m1/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019221
PNG
(CHEMBL308756 | N-(2-Oxo-5-phenyl-2,3-dihydro-1H-be...)
Show SMILES CCCc1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C25H23N3O2/c1-2-8-17-13-15-19(16-14-17)24(29)28-23-25(30)26-21-12-7-6-11-20(21)22(27-23)18-9-4-3-5-10-18/h3-7,9-16,23H,2,8H2,1H3,(H,26,30)(H,28,29)
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n/an/a 8.00E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019251
PNG
(4-Hydroxy-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e...)
Show SMILES Oc1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C22H17N3O3/c26-16-12-10-15(11-13-16)21(27)25-20-22(28)23-18-9-5-4-8-17(18)19(24-20)14-6-2-1-3-7-14/h1-13,20,26H,(H,23,28)(H,25,27)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019262
PNG
(Biphenyl-4-carboxylic acid (2-oxo-5-phenyl-2,3-dih...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H21N3O2/c32-27(22-17-15-20(16-18-22)19-9-3-1-4-10-19)31-26-28(33)29-24-14-8-7-13-23(24)25(30-26)21-11-5-2-6-12-21/h1-18,26H,(H,29,33)(H,31,32)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50367638
PNG
(CHEMBL1907660)
Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)C(C)(C)C)C1=O)c1ccccc1
Show InChI InChI=1S/C21H23N3O2/c1-21(2,3)20(26)23-18-19(25)24(4)16-13-9-8-12-15(16)17(22-18)14-10-6-5-7-11-14/h5-13,18H,1-4H3,(H,23,26)/t18-/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019269
PNG
(4-Cyano-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C23H16N4O2/c24-14-15-10-12-17(13-11-15)22(28)27-21-23(29)25-19-9-5-4-8-18(19)20(26-21)16-6-2-1-3-7-16/h1-13,21H,(H,25,29)(H,27,28)
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n/an/a 2.20E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019214
PNG
(4-tert-Butyl-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C26H25N3O2/c1-26(2,3)19-15-13-18(14-16-19)24(30)29-23-25(31)27-21-12-8-7-11-20(21)22(28-23)17-9-5-4-6-10-17/h4-16,23H,1-3H3,(H,27,31)(H,29,30)
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n/an/a 4.00E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019262
PNG
(Biphenyl-4-carboxylic acid (2-oxo-5-phenyl-2,3-dih...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H21N3O2/c32-27(22-17-15-20(16-18-22)19-9-3-1-4-10-19)31-26-28(33)29-24-14-8-7-13-23(24)25(30-26)21-11-5-2-6-12-21/h1-18,26H,(H,29,33)(H,31,32)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019232
PNG
(CHEMBL309017 | Naphthalene-1-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cccc2ccccc12
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-8-12-17-9-4-5-13-19(17)20)29-24-26(31)27-22-16-7-6-14-21(22)23(28-24)18-10-2-1-3-11-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 2.90E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019269
PNG
(4-Cyano-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C23H16N4O2/c24-14-15-10-12-17(13-11-15)22(28)27-21-23(29)25-19-9-5-4-8-18(19)20(26-21)16-6-2-1-3-7-16/h1-13,21H,(H,25,29)(H,27,28)
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n/an/a 730n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019274
PNG
(CCK antagonist synthetic 16 | CHEMBL72057 | N-[5-(...)
Show SMILES CC(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O
Show InChI InChI=1S/C17H14FN3O2/c1-10(22)19-16-17(23)20-14-9-5-3-7-12(14)15(21-16)11-6-2-4-8-13(11)18/h2-9,16H,1H3,(H,19,22)(H,20,23)
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n/an/a>4.00E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019188
PNG
(CHEMBL422951 | Naphthalene-2-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-14-17-8-4-5-11-19(17)16-20)29-24-26(31)27-22-13-7-6-12-21(22)23(28-24)18-9-2-1-3-10-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 20n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019214
PNG
(4-tert-Butyl-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C26H25N3O2/c1-26(2,3)19-15-13-18(14-16-19)24(30)29-23-25(31)27-21-12-8-7-11-20(21)22(28-23)17-9-5-4-6-10-17/h4-16,23H,1-3H3,(H,27,31)(H,29,30)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019274
PNG
(CCK antagonist synthetic 16 | CHEMBL72057 | N-[5-(...)
Show SMILES CC(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O
Show InChI InChI=1S/C17H14FN3O2/c1-10(22)19-16-17(23)20-14-9-5-3-7-12(14)15(21-16)11-6-2-4-8-13(11)18/h2-9,16H,1H3,(H,19,22)(H,20,23)
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n/an/a 4.00E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50367630
PNG
(CHEMBL1907665)
Show SMILES CC(C)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O
Show InChI InChI=1S/C20H21N3O2/c1-13(2)19(24)22-18-20(25)23(3)16-12-8-7-11-15(16)17(21-18)14-9-5-4-6-10-14/h4-13,18H,1-3H3,(H,22,24)/t18-/m1/s1
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n/an/a 7.30E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019251
PNG
(4-Hydroxy-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e...)
Show SMILES Oc1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C22H17N3O3/c26-16-12-10-15(11-13-16)21(27)25-20-22(28)23-18-9-5-4-8-17(18)19(24-20)14-6-2-1-3-7-14/h1-13,20,26H,(H,23,28)(H,25,27)
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n/an/a 3.10E+4n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50019183
PNG
(3-Amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin...)
Show SMILES NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C15H13N3O/c16-14-15(19)17-12-9-5-4-8-11(12)13(18-14)10-6-2-1-3-7-10/h1-9,14H,16H2,(H,17,19)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands


J Med Chem 31: 2235-46 (1989)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019262
PNG
(Biphenyl-4-carboxylic acid (2-oxo-5-phenyl-2,3-dih...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H21N3O2/c32-27(22-17-15-20(16-18-22)19-9-3-1-4-10-19)31-26-28(33)29-24-14-8-7-13-23(24)25(30-26)21-11-5-2-6-12-21/h1-18,26H,(H,29,33)(H,31,32)
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019188
PNG
(CHEMBL422951 | Naphthalene-2-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-14-17-8-4-5-11-19(17)16-20)29-24-26(31)27-22-13-7-6-12-21(22)23(28-24)18-9-2-1-3-10-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 19.9n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019269
PNG
(4-Cyano-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C23H16N4O2/c24-14-15-10-12-17(13-11-15)22(28)27-21-23(29)25-19-9-5-4-8-18(19)20(26-21)16-6-2-1-3-7-16/h1-13,21H,(H,25,29)(H,27,28)
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n/an/a 724n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019214
PNG
(4-tert-Butyl-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C26H25N3O2/c1-26(2,3)19-15-13-18(14-16-19)24(30)29-23-25(31)27-21-12-8-7-11-20(21)22(28-23)17-9-5-4-6-10-17/h4-16,23H,1-3H3,(H,27,31)(H,29,30)
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n/an/a 1.41E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019251
PNG
(4-Hydroxy-N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e...)
Show SMILES Oc1ccc(cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1S/C22H17N3O3/c26-16-12-10-15(11-13-16)21(27)25-20-22(28)23-18-9-5-4-8-17(18)19(24-20)14-6-2-1-3-7-14/h1-13,20,26H,(H,23,28)(H,25,27)
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n/an/a 1.78E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50019232
PNG
(CHEMBL309017 | Naphthalene-1-carboxylic acid (2-ox...)
Show SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cccc2ccccc12
Show InChI InChI=1S/C26H19N3O2/c30-25(20-15-8-12-17-9-4-5-13-19(17)20)29-24-26(31)27-22-16-7-6-14-21(22)23(28-24)18-10-2-1-3-11-18/h1-16,24H,(H,27,31)(H,29,30)
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n/an/a 1.58E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Binding affinity against cholecystokinin type A receptor of rat pancreas


J Med Chem 37: 3639-54 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50043532
PNG
((1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1...)
Show SMILES CN1c2ccccc2C(=NC(NC(N)=O)C1=O)c1ccccc1
Show InChI InChI=1S/C17H16N4O2/c1-21-13-10-6-5-9-12(13)14(11-7-3-2-4-8-11)19-15(16(21)22)20-17(18)23/h2-10,15H,1H3,(H3,18,20,23)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue


J Med Chem 36: 4276-92 (1994)

More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50043532
PNG
((1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1...)
Show SMILES CN1c2ccccc2C(=NC(NC(N)=O)C1=O)c1ccccc1
Show InChI InChI=1S/C17H16N4O2/c1-21-13-10-6-5-9-12(13)14(11-7-3-2-4-8-11)19-15(16(21)22)20-17(18)23/h2-10,15H,1H3,(H3,18,20,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor


J Med Chem 36: 4276-92 (1994)

More data for this
Ligand-Target Pair