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5 similar compounds to monomer 50020843

Compile data set for download or QSAR
Wt: 263.1
BDBM50021114
Wt: 306.2
BDBM50021121
Wt: 292.2
BDBM50021123
Wt: 278.2
BDBM50021124
Wt: 266.1
BDBM50406958

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021114,50021121,50021123,50021124,50406958   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021123
PNG
(CHEMBL30505 | dipotassium (2S)-1-{(2S)-2-[(ethoxyp...)
Show SMILES CCOP([O-])(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C([O-])=O
Show InChI InChI=1S/C10H19N2O6P/c1-3-18-19(16,17)11-7(2)9(13)12-6-4-5-8(12)10(14)15/h7-8H,3-6H2,1-2H3,(H,14,15)(H2,11,16,17)/p-2/t7-,8-/m0/s1
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PC cid
PC sid
UniChem

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Article
PubMed
1.20n/an/an/an/an/an/a7.5n/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme from rabbit lungs at pH 7.5


J Med Chem 28: 1422-7 (1985)


Article DOI: 10.1021/jm00148a008
BindingDB Entry DOI: 10.7270/Q2Z60N24
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021114
PNG
(CHEMBL282987 | tripotassium (2S)-1-[(2S)-2-(phosph...)
Show SMILES C[C@H](NP([O-])([O-])=O)C(=O)N1CCC[C@H]1C([O-])=O
Show InChI InChI=1S/C8H15N2O6P/c1-5(9-17(14,15)16)7(11)10-4-2-3-6(10)8(12)13/h5-6H,2-4H2,1H3,(H,12,13)(H3,9,14,15,16)/p-3/t5-,6-/m0/s1
MMDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.40n/an/an/an/an/an/a7.5n/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme from rabbit lungs at pH 7.5


J Med Chem 28: 1422-7 (1985)


Article DOI: 10.1021/jm00148a008
BindingDB Entry DOI: 10.7270/Q2Z60N24
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021121
PNG
(CHEMBL286181 | dipotassium (2S)-1-{(2S)-2-[(isopro...)
Show SMILES CC(C)OP([O-])(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C([O-])=O
Show InChI InChI=1S/C11H21N2O6P/c1-7(2)19-20(17,18)12-8(3)10(14)13-6-4-5-9(13)11(15)16/h7-9H,4-6H2,1-3H3,(H,15,16)(H2,12,17,18)/p-2/t8-,9-/m0/s1
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.40n/an/an/an/an/an/a7.5n/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme from rabbit lungs at pH 7.5


J Med Chem 28: 1422-7 (1985)


Article DOI: 10.1021/jm00148a008
BindingDB Entry DOI: 10.7270/Q2Z60N24
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021124
PNG
(CHEMBL34402 | dipotassium (2S)-1-{(2S)-2-[(methoxy...)
Show SMILES COP([O-])(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C([O-])=O
Show InChI InChI=1S/C9H17N2O6P/c1-6(10-18(15,16)17-2)8(12)11-5-3-4-7(11)9(13)14/h6-7H,3-5H2,1-2H3,(H,13,14)(H2,10,15,16)/p-2/t6-,7-/m0/s1
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Article
PubMed
2.60n/an/an/an/an/an/a7.5n/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme from rabbit lungs at pH 7.5


J Med Chem 28: 1422-7 (1985)


Article DOI: 10.1021/jm00148a008
BindingDB Entry DOI: 10.7270/Q2Z60N24
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50406958
PNG
(CHEMBL78443)
Show SMILES C[C@H](NP(O)(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C8H15N2O6P/c1-5(9-17(14,15)16)7(11)10-4-2-3-6(10)8(12)13/h5-6H,2-4H2,1H3,(H,12,13)(H3,9,14,15,16)/t5-,6-/m0/s1
PDB
MMDB

Reactome pathway
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UniChem

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Article
PubMed
n/an/a 776n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibitory activity against angiotensin converting enzyme (ACE)


J Med Chem 36: 2390-403 (1993)


Article DOI: 10.1021/jm00068a017
BindingDB Entry DOI: 10.7270/Q2Z320V9
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021114
PNG
(CHEMBL282987 | tripotassium (2S)-1-[(2S)-2-(phosph...)
Show SMILES C[C@H](NP([O-])([O-])=O)C(=O)N1CCC[C@H]1C([O-])=O
Show InChI InChI=1S/C8H15N2O6P/c1-5(9-17(14,15)16)7(11)10-4-2-3-6(10)8(12)13/h5-6H,2-4H2,1H3,(H,12,13)(H3,9,14,15,16)/p-3/t5-,6-/m0/s1
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against Angiotensin I converting enzyme was evaluated


J Med Chem 28: 1422-7 (1985)


Article DOI: 10.1021/jm00148a008
BindingDB Entry DOI: 10.7270/Q2Z60N24
More data for this
Ligand-Target Pair