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11 similar compounds to monomer 50029302

Compile data set for download or QSAR
Wt: 339.4
BDBM50029295
Wt: 421.5
BDBM50029300
Wt: 395.5
BDBM50029305
Wt: 435.5
BDBM50029309
Wt: 443.5
BDBM50029310
Wt: 324.4
BDBM50029312
Wt: 421.5
BDBM50029321
Wt: 409.5
BDBM50064570
Wt: 409.5
BDBM50064535
Wt: 393.5
BDBM50064541
Wt: 353.4
BDBM50064544
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50029295,50029300,50029305,50029309,50029310,50029312,50029321,50064570,50064535,50064541,50064544   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50064570
PNG
(CHEMBL64227 | N,N-Diethyl-3-[4-(2-isopropoxy-pheny...)
Show SMILES CCN(CC)C(=O)c1cccc(CN2CCN(CC2)c2ccccc2OC(C)C)c1
Show InChI InChI=1S/C25H35N3O2/c1-5-27(6-2)25(29)22-11-9-10-21(18-22)19-26-14-16-28(17-15-26)23-12-7-8-13-24(23)30-20(3)4/h7-13,18,20H,5-6,14-17,19H2,1-4H3
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2.10n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortex


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50064535
PNG
(CHEMBL61963 | N-Acetyl-3-[4-(2-isopropoxy-phenyl)-...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N(C)C(C)=O)CC1
Show InChI InChI=1S/C24H31N3O3/c1-18(2)30-23-11-6-5-10-22(23)27-14-12-26(13-15-27)17-20-8-7-9-21(16-20)24(29)25(4)19(3)28/h5-11,16,18H,12-15,17H2,1-4H3
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3.30n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortex


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50064541
PNG
(Azetidin-1-yl-{3-[4-(2-isopropoxy-phenyl)-piperazi...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCC2)CC1
Show InChI InChI=1S/C24H31N3O2/c1-19(2)29-23-10-4-3-9-22(23)26-15-13-25(14-16-26)18-20-7-5-8-21(17-20)24(28)27-11-6-12-27/h3-5,7-10,17,19H,6,11-16,18H2,1-2H3
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3.40n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortex


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029310
PNG
(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNC(=O)c3ccccc3)c2)CC1
Show InChI InChI=1S/C28H33N3O2/c1-22(2)33-27-14-7-6-13-26(27)31-17-15-30(16-18-31)21-24-10-8-9-23(19-24)20-29-28(32)25-11-4-3-5-12-25/h3-14,19,22H,15-18,20-21H2,1-2H3,(H,29,32)
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3.70n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029312
PNG
(1-(2-Isopropoxy-phenyl)-4-(3-methyl-benzyl)-pipera...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(C)c2)CC1
Show InChI InChI=1S/C21H28N2O/c1-17(2)24-21-10-5-4-9-20(21)23-13-11-22(12-14-23)16-19-8-6-7-18(3)15-19/h4-10,15,17H,11-14,16H2,1-3H3
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6.20n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029321
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCC3=O)c2)CC1
Show InChI InChI=1S/C25H31N3O3/c1-19(2)31-23-9-4-3-8-22(23)27-14-12-26(13-15-27)17-20-6-5-7-21(16-20)18-28-24(29)10-11-25(28)30/h3-9,16,19H,10-15,17-18H2,1-2H3
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8n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029309
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCCC3=O)c2)CC1
Show InChI InChI=1S/C26H33N3O3/c1-20(2)32-24-10-4-3-9-23(24)28-15-13-27(14-16-28)18-21-7-5-8-22(17-21)19-29-25(30)11-6-12-26(29)31/h3-5,7-10,17,20H,6,11-16,18-19H2,1-2H3
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8.60n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029300
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1
Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3
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10n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor of rat brain synaptosomal preparations


J Med Chem 37: 1060-2 (1994)


Article DOI: 10.1021/jm00034a003
BindingDB Entry DOI: 10.7270/Q23R0RXB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029300
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1
Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3
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10n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50064541
PNG
(Azetidin-1-yl-{3-[4-(2-isopropoxy-phenyl)-piperazi...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCC2)CC1
Show InChI InChI=1S/C24H31N3O2/c1-19(2)29-23-10-4-3-9-22(23)26-15-13-25(14-16-26)18-20-7-5-8-21(17-20)24(28)27-11-6-12-27/h3-5,7-10,17,19H,6,11-16,18H2,1-2H3
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13n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat striatum


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50064570
PNG
(CHEMBL64227 | N,N-Diethyl-3-[4-(2-isopropoxy-pheny...)
Show SMILES CCN(CC)C(=O)c1cccc(CN2CCN(CC2)c2ccccc2OC(C)C)c1
Show InChI InChI=1S/C25H35N3O2/c1-5-27(6-2)25(29)22-11-9-10-21(18-22)19-26-14-16-28(17-15-26)23-12-7-8-13-24(23)30-20(3)4/h7-13,18,20H,5-6,14-17,19H2,1-4H3
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14n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat striatum


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029305
PNG
(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN(C)C(C)=O)c2)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19(2)29-24-11-6-5-10-23(24)27-14-12-26(13-15-27)18-22-9-7-8-21(16-22)17-25(4)20(3)28/h5-11,16,19H,12-15,17-18H2,1-4H3
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17n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50064544
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(N)=O)CC1
Show InChI InChI=1S/C21H27N3O2/c1-16(2)26-20-9-4-3-8-19(20)24-12-10-23(11-13-24)15-17-6-5-7-18(14-17)21(22)25/h3-9,14,16H,10-13,15H2,1-2H3,(H2,22,25)
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18n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortex


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029310
PNG
(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNC(=O)c3ccccc3)c2)CC1
Show InChI InChI=1S/C28H33N3O2/c1-22(2)33-27-14-7-6-13-26(27)31-17-15-30(16-18-31)21-24-10-8-9-23(19-24)20-29-28(32)25-11-4-3-5-12-25/h3-14,19,22H,15-18,20-21H2,1-2H3,(H,29,32)
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20n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029305
PNG
(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN(C)C(C)=O)c2)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19(2)29-24-11-6-5-10-23(24)27-14-12-26(13-15-27)18-22-9-7-8-21(16-22)17-25(4)20(3)28/h5-11,16,19H,12-15,17-18H2,1-4H3
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22n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the dopamine receptor D2 using [3H]spiperinone.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029295
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-21-9-4-3-8-20(21)24-12-10-23(11-13-24)16-19-7-5-6-18(14-19)15-22/h3-9,14,17H,10-13,15-16,22H2,1-2H3
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31n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029295
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-21-9-4-3-8-20(21)24-12-10-23(11-13-24)16-19-7-5-6-18(14-19)15-22/h3-9,14,17H,10-13,15-16,22H2,1-2H3
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32n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029309
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCCC3=O)c2)CC1
Show InChI InChI=1S/C26H33N3O3/c1-20(2)32-24-10-4-3-9-23(24)28-15-13-27(14-16-28)18-21-7-5-8-22(17-21)19-29-25(30)11-6-12-26(29)31/h3-5,7-10,17,20H,6,11-16,18-19H2,1-2H3
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63n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the dopamine receptor D2 using [3H]spiperinone.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029321
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCC3=O)c2)CC1
Show InChI InChI=1S/C25H31N3O3/c1-19(2)31-23-9-4-3-8-22(23)27-14-12-26(13-15-27)17-20-6-5-7-21(16-20)18-28-24(29)10-11-25(28)30/h3-9,16,19H,10-15,17-18H2,1-2H3
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94n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029300
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1
Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3
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120n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the dopamine receptor D2 using [3H]spiperinone.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029300
PNG
(1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1
Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3
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120n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine D2 receptors in rat brain synaptosomal preparations


J Med Chem 37: 1060-2 (1994)


Article DOI: 10.1021/jm00034a003
BindingDB Entry DOI: 10.7270/Q23R0RXB
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50064544
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(N)=O)CC1
Show InChI InChI=1S/C21H27N3O2/c1-16(2)26-20-9-4-3-8-19(20)24-12-10-23(11-13-24)15-17-6-5-7-18(14-17)21(22)25/h3-9,14,16H,10-13,15H2,1-2H3,(H2,22,25)
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146n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat striatum


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50064535
PNG
(CHEMBL61963 | N-Acetyl-3-[4-(2-isopropoxy-phenyl)-...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N(C)C(C)=O)CC1
Show InChI InChI=1S/C24H31N3O3/c1-18(2)30-23-11-6-5-10-22(23)27-14-12-26(13-15-27)17-20-8-7-9-21(16-20)24(29)25(4)19(3)28/h5-11,16,18H,12-15,17H2,1-4H3
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158n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat striatum


J Med Chem 41: 1997-2009 (1998)


Article DOI: 10.1021/jm970164z
BindingDB Entry DOI: 10.7270/Q2KK9CG0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029312
PNG
(1-(2-Isopropoxy-phenyl)-4-(3-methyl-benzyl)-pipera...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(C)c2)CC1
Show InChI InChI=1S/C21H28N2O/c1-17(2)24-21-10-5-4-9-20(21)23-13-11-22(12-14-23)16-19-8-6-7-18(3)15-19/h4-10,15,17H,11-14,16H2,1-3H3
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302n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the dopamine receptor D2 using [3H]spiperinone.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair