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3 similar compounds to monomer 50288855

Compile data set for download or QSAR
Wt: 245.3
BDBM50413900
Wt: 233.3
BDBM50030340
Wt: 221.2
BDBM50030341

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413900,50030340,50030341   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysosomal alpha-mannosidase


(Homo sapiens (Human))
BDBM50030340
PNG
(CHEMBL3344203)
Show SMILES CCCCN1C[C@H](O)C(O)(CCO)[C@H](O)C1
Show InChI InChI=1S/C11H23NO4/c1-2-3-5-12-7-9(14)11(16,4-6-13)10(15)8-12/h9-10,13-16H,2-8H2,1H3/t9-,10+,11?
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.52E+5n/an/an/an/an/an/a



University of Pune

Curated by ChEMBL


Assay Description
Inhibition of alpha-mannosidase (unknown origin) using p-nitrophenyl-alpha-D-mannopyranoside substrate incubated for 10 mins by UV spectrophotometry


Bioorg Med Chem 22: 5776-82 (2014)


Article DOI: 10.1016/j.bmc.2014.09.034
BindingDB Entry DOI: 10.7270/Q2930VRN
More data for this
Ligand-Target Pair
Glucosylceramidase


(Homo sapiens (Human))
BDBM50413900
PNG
(CHEMBL490751)
Show SMILES CCCCCCCCN1C[C@@H](O)C(O)[C@H](O)C1
Show InChI InChI=1S/C13H27NO3/c1-2-3-4-5-6-7-8-14-9-11(15)13(17)12(16)10-14/h11-13,15-17H,2-10H2,1H3/t11-,12-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human placental beta-glucocerebrosidase


J Med Chem 52: 3146-9 (2009)


Article DOI: 10.1021/jm801506m
BindingDB Entry DOI: 10.7270/Q26W9CBW
More data for this
Ligand-Target Pair
Lysosomal alpha-mannosidase


(Homo sapiens (Human))
BDBM50030341
PNG
(CHEMBL3344207)
Show SMILES OCCN1C[C@H](O)C(O)(CCO)[C@H](O)C1
Show InChI InChI=1S/C9H19NO5/c11-3-1-9(15)7(13)5-10(2-4-12)6-8(9)14/h7-8,11-15H,1-6H2/t7-,8+,9?
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8.73E+5n/an/an/an/an/an/a



University of Pune

Curated by ChEMBL


Assay Description
Inhibition of alpha-mannosidase (unknown origin) using p-nitrophenyl-alpha-D-mannopyranoside substrate incubated for 10 mins by UV spectrophotometry


Bioorg Med Chem 22: 5776-82 (2014)


Article DOI: 10.1016/j.bmc.2014.09.034
BindingDB Entry DOI: 10.7270/Q2930VRN
More data for this
Ligand-Target Pair