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22 similar compounds to monomer 50156167

Compile data set for download or QSAR
Wt: 525.6
BDBM50156168
Wt: 553.7
BDBM50156172
Wt: 475.6
BDBM50156173
Purchase
Wt: 526.6
BDBM50156174
Wt: 475.6
BDBM50199312
Wt: 475.6
BDBM50199315
Wt: 447.5
BDBM50199316
Wt: 529.5
BDBM50199319
Wt: 539.6
BDBM50199323
Wt: 461.5
BDBM50199324
Wt: 475.6
BDBM50199327
Wt: 477.5
BDBM50199328
Wt: 477.5
BDBM50199330
Wt: 461.5
BDBM50199332
Wt: 503.6
BDBM50321064
Displayed 1 to 15 (of 22 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50156168,50156172,50156173,50156174,50199312,50199315,50199316,50199319,50199323,50199324,50199327,50199328,50199330,50199332,50321064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Binding affinity to AT2 receptor (unknown origin)


ACS Med Chem Lett 5: 1129-32 (2014)


Article DOI: 10.1021/ml500278g
BindingDB Entry DOI: 10.7270/Q2BV7J7R
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity to AT2 receptor


Bioorg Med Chem 18: 4570-90 (2010)


Article DOI: 10.1016/j.bmc.2010.03.064
BindingDB Entry DOI: 10.7270/Q2VD70F0
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor


J Med Chem 47: 5995-6008 (2004)


Article DOI: 10.1021/jm049715t
BindingDB Entry DOI: 10.7270/Q29Z95PH
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Sus scrofa)
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane


Bioorg Med Chem 16: 6841-9 (2008)


Article DOI: 10.1016/j.bmc.2008.05.066
BindingDB Entry DOI: 10.7270/Q22F7N7C
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity to type-2 angiotensin-2 receptor (unknown origin)


Bioorg Med Chem Lett 26: 1355-9 (2016)


Article DOI: 10.1016/j.bmcl.2015.10.084
BindingDB Entry DOI: 10.7270/Q2SN0BT6
More data for this
Ligand-Target Pair
Angiotensin type II receptor


(Sus scrofa)
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity to pig AT2 receptor


Bioorg Med Chem Lett 24: 476-9 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.040
BindingDB Entry DOI: 10.7270/Q2B859KQ
More data for this
Ligand-Target Pair
Angiotensin type II receptor


(Sus scrofa)
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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0.400n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting


Bioorg Med Chem 18: 4570-90 (2010)


Article DOI: 10.1016/j.bmc.2010.03.064
BindingDB Entry DOI: 10.7270/Q2VD70F0
More data for this
Ligand-Target Pair
Angiotensin type II receptor


(Sus scrofa)
BDBM50321064
PNG
(CHEMBL1165175 | N-Butyloxycarbonyl-3-[4-(1-methyl-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)c1nccn1C
Show InChI InChI=1S/C24H29N3O5S2/c1-5-6-13-32-24(29)26-34(30,31)23-20(15-19(33-23)14-16(2)3)17-7-9-18(10-8-17)21(28)22-25-11-12-27(22)4/h7-12,15-16H,5-6,13-14H2,1-4H3,(H,26,29)
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2.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting


Bioorg Med Chem 18: 4570-90 (2010)


Article DOI: 10.1016/j.bmc.2010.03.064
BindingDB Entry DOI: 10.7270/Q2VD70F0
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156172
PNG
(CHEMBL190577 | butyl (5-isobutylthien-2-yl)sulfony...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3ccccc23)cc1
Show InChI InChI=1S/C29H35N3O4S2/c1-5-7-16-36-29(33)31-38(34,35)28-24(18-23(37-28)17-20(3)4)22-14-12-21(13-15-22)19-32-26-11-9-8-10-25(26)30-27(32)6-2/h8-15,18,20H,5-7,16-17,19H2,1-4H3,(H,31,33)
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3.20n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor


J Med Chem 47: 5995-6008 (2004)


Article DOI: 10.1021/jm049715t
BindingDB Entry DOI: 10.7270/Q29Z95PH
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156168
PNG
(CHEMBL366210 | butyl (5-isobutylthien-2-yl)sulfony...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2cnc3ccccc23)cc1
Show InChI InChI=1S/C27H31N3O4S2/c1-4-5-14-34-27(31)29-36(32,33)26-23(16-22(35-26)15-19(2)3)21-12-10-20(11-13-21)17-30-18-28-24-8-6-7-9-25(24)30/h6-13,16,18-19H,4-5,14-15,17H2,1-3H3,(H,29,31)
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4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor


J Med Chem 47: 5995-6008 (2004)


Article DOI: 10.1021/jm049715t
BindingDB Entry DOI: 10.7270/Q29Z95PH
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199312
PNG
(CHEMBL217249 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-3-5-7-20-15-21(19-10-8-18(9-11-19)16-26-13-12-24-17-26)22(31-20)32(28,29)25-23(27)30-14-6-4-2/h8-13,15,17H,3-7,14,16H2,1-2H3,(H,25,27)
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5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199332
PNG
(CHEMBL216688 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O4S2/c1-3-5-13-29-22(26)24-31(27,28)21-20(14-19(30-21)6-4-2)18-9-7-17(8-10-18)15-25-12-11-23-16-25/h7-12,14,16H,3-6,13,15H2,1-2H3,(H,24,26)
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6n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156174
PNG
(CHEMBL190811 | butyl (5-isobutylthien-2-yl)sulfony...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2cnc3cccnc23)cc1
Show InChI InChI=1S/C26H30N4O4S2/c1-4-5-13-34-26(31)29-36(32,33)25-22(15-21(35-25)14-18(2)3)20-10-8-19(9-11-20)16-30-17-28-23-7-6-12-27-24(23)30/h6-12,15,17-18H,4-5,13-14,16H2,1-3H3,(H,29,31)
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7.10n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor


J Med Chem 47: 5995-6008 (2004)


Article DOI: 10.1021/jm049715t
BindingDB Entry DOI: 10.7270/Q29Z95PH
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199316
PNG
(CHEMBL386269 | N-ethyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C21H25N3O4S2/c1-4-28-21(25)23-30(26,27)20-19(12-18(29-20)11-15(2)3)17-7-5-16(6-8-17)13-24-10-9-22-14-24/h5-10,12,14-15H,4,11,13H2,1-3H3,(H,23,25)
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10n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199328
PNG
(CHEMBL386172 | N-(methyloxy-ethyloxycarbonyl)-3-(4...)
Show SMILES COCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O5S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-25-9-8-23-15-25)21(31-19)32(27,28)24-22(26)30-11-10-29-3/h4-9,13,15-16H,10-12,14H2,1-3H3,(H,24,26)
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31n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199315
PNG
(CHEMBL384577 | N-iso-Butyloxycarbonyl-3-(4-imidazo...)
Show SMILES CC(C)COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)11-20-12-21(19-7-5-18(6-8-19)13-26-10-9-24-15-26)22(31-20)32(28,29)25-23(27)30-14-17(3)4/h5-10,12,15-17H,11,13-14H2,1-4H3,(H,25,27)
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37n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199327
PNG
(CHEMBL386671 | N-tert-butyloxycarbonyl-3-(4-imidaz...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OC(C)(C)C)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)12-19-13-20(18-8-6-17(7-9-18)14-26-11-10-24-15-26)21(31-19)32(28,29)25-22(27)30-23(3,4)5/h6-11,13,15-16H,12,14H2,1-5H3,(H,25,27)
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63n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199324
PNG
(CHEMBL215159 | N-iso-propyloxycarbonyl-3-(4-imidaz...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OC(C)C)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O4S2/c1-15(2)11-19-12-20(21(30-19)31(27,28)24-22(26)29-16(3)4)18-7-5-17(6-8-18)13-25-10-9-23-14-25/h5-10,12,14-16H,11,13H2,1-4H3,(H,24,26)
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75n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199330
PNG
(CHEMBL217752 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCOC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O5S2/c1-3-4-12-30-22(26)24-32(27,28)21-20(14-19(31-21)9-13-29-2)18-7-5-17(6-8-18)15-25-11-10-23-16-25/h5-8,10-11,14,16H,3-4,9,12-13,15H2,1-2H3,(H,24,26)
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86n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199323
PNG
(CHEMBL214671 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(Cc2cccc(OC)c2)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C27H29N3O5S2/c1-3-4-14-35-27(31)29-37(32,33)26-25(17-24(36-26)16-21-6-5-7-23(15-21)34-2)22-10-8-20(9-11-22)18-30-13-12-28-19-30/h5-13,15,17,19H,3-4,14,16,18H2,1-2H3,(H,29,31)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199319
PNG
(CHEMBL217084 | N-(4,4,4-triflouro-butyloxycarbonyl...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OCCCC(F)(F)F)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H26F3N3O4S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-29-10-9-27-15-29)21(34-19)35(31,32)28-22(30)33-11-3-8-23(24,25)26/h4-7,9-10,13,15-16H,3,8,11-12,14H2,1-2H3,(H,28,30)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199315
PNG
(CHEMBL384577 | N-iso-Butyloxycarbonyl-3-(4-imidazo...)
Show SMILES CC(C)COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)11-20-12-21(19-7-5-18(6-8-19)13-26-10-9-24-15-26)22(31-20)32(28,29)25-23(27)30-14-17(3)4/h5-10,12,15-17H,11,13-14H2,1-4H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199312
PNG
(CHEMBL217249 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-3-5-7-20-15-21(19-10-8-18(9-11-19)16-26-13-12-24-17-26)22(31-20)32(28,29)25-23(27)30-14-6-4-2/h8-13,15,17H,3-7,14,16H2,1-2H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
AGTR1


(RAT)
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ang II from AT1 receptor in rat liver membranes after 2 hrs by gamma-counting method


ACS Med Chem Lett 6: 178-82 (2015)


Article DOI: 10.1021/ml500427r
BindingDB Entry DOI: 10.7270/Q2HD7X98
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity to AT1 receptor


Bioorg Med Chem 18: 4570-90 (2010)


Article DOI: 10.1016/j.bmc.2010.03.064
BindingDB Entry DOI: 10.7270/Q2VD70F0
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Binding affinity to AT1 receptor (unknown origin)


ACS Med Chem Lett 5: 1129-32 (2014)


Article DOI: 10.1021/ml500278g
BindingDB Entry DOI: 10.7270/Q2BV7J7R
More data for this
Ligand-Target Pair
AGTR1


(RAT)
BDBM50156173
PNG
((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125]Ang2 from AT1 receptor in rat liver membrane


Bioorg Med Chem 16: 6841-9 (2008)


Article DOI: 10.1016/j.bmc.2008.05.066
BindingDB Entry DOI: 10.7270/Q22F7N7C
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199319
PNG
(CHEMBL217084 | N-(4,4,4-triflouro-butyloxycarbonyl...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OCCCC(F)(F)F)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H26F3N3O4S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-29-10-9-27-15-29)21(34-19)35(31,32)28-22(30)33-11-3-8-23(24,25)26/h4-7,9-10,13,15-16H,3,8,11-12,14H2,1-2H3,(H,28,30)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199324
PNG
(CHEMBL215159 | N-iso-propyloxycarbonyl-3-(4-imidaz...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OC(C)C)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O4S2/c1-15(2)11-19-12-20(21(30-19)31(27,28)24-22(26)29-16(3)4)18-7-5-17(6-8-18)13-25-10-9-23-14-25/h5-10,12,14-16H,11,13H2,1-4H3,(H,24,26)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199327
PNG
(CHEMBL386671 | N-tert-butyloxycarbonyl-3-(4-imidaz...)
Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OC(C)(C)C)-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)12-19-13-20(18-8-6-17(7-9-18)14-26-11-10-24-15-26)21(31-19)32(28,29)25-22(27)30-23(3,4)5/h6-11,13,15-16H,12,14H2,1-5H3,(H,25,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199328
PNG
(CHEMBL386172 | N-(methyloxy-ethyloxycarbonyl)-3-(4...)
Show SMILES COCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O5S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-25-9-8-23-15-25)21(31-19)32(27,28)24-22(26)30-11-10-29-3/h4-9,13,15-16H,10-12,14H2,1-3H3,(H,24,26)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199330
PNG
(CHEMBL217752 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCOC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O5S2/c1-3-4-12-30-22(26)24-32(27,28)21-20(14-19(31-21)9-13-29-2)18-7-5-17(6-8-18)15-25-11-10-23-16-25/h5-8,10-11,14,16H,3-4,9,12-13,15H2,1-2H3,(H,24,26)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199332
PNG
(CHEMBL216688 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCC)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C22H27N3O4S2/c1-3-5-13-29-22(26)24-31(27,28)21-20(14-19(30-21)6-4-2)18-9-7-17(8-10-18)15-25-12-11-23-16-25/h7-12,14,16H,3-6,13,15H2,1-2H3,(H,24,26)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50199323
PNG
(CHEMBL214671 | N-butyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(Cc2cccc(OC)c2)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C27H29N3O5S2/c1-3-4-14-35-27(31)29-37(32,33)26-25(17-24(36-26)16-21-6-5-7-23(15-21)34-2)22-10-8-20(9-11-22)18-30-13-12-28-19-30/h5-13,15,17,19H,3-4,14,16,18H2,1-2H3,(H,29,31)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50199316
PNG
(CHEMBL386269 | N-ethyloxycarbonyl-3-(4-imidazol-1-...)
Show SMILES CCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
Show InChI InChI=1S/C21H25N3O4S2/c1-4-28-21(25)23-30(26,27)20-19(12-18(29-20)11-15(2)3)17-7-5-16(6-8-17)13-24-10-9-22-14-24/h5-10,12,14-15H,4,11,13H2,1-3H3,(H,23,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane


J Med Chem 49: 7160-8 (2006)


Article DOI: 10.1021/jm0606185
BindingDB Entry DOI: 10.7270/Q21C1WHK
More data for this
Ligand-Target Pair