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1 similar compounds to monomer 85709

Compile data set for download or QSAR
Wt: 236.6
BDBM50031306

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031306   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50031306
PNG
(8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(...)
Show SMILES NC1=NC2(CO1)CCc1cccc(Cl)c1C2
Show InChI InChI=1S/C12H13ClN2O/c13-10-3-1-2-8-4-5-12(6-9(8)10)7-16-11(14)15-12/h1-3H,4-7H2,(H2,14,15)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Binding affinity towards Alpha-2A adrenergic receptor in human platelets using [3H]-RX-821002 as radioligand


J Med Chem 38: 4056-69 (1995)


Article DOI: 10.1021/jm00020a021
BindingDB Entry DOI: 10.7270/Q2DV1HXN
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM50031306
PNG
(8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(...)
Show SMILES NC1=NC2(CO1)CCc1cccc(Cl)c1C2
Show InChI InChI=1S/C12H13ClN2O/c13-10-3-1-2-8-4-5-12(6-9(8)10)7-16-11(14)15-12/h1-3H,4-7H2,(H2,14,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Binding affinity towards Alpha-2B adrenergic receptor in neonatal rat lung using [3H]-RX-821002 as radioligand


J Med Chem 38: 4056-69 (1995)


Article DOI: 10.1021/jm00020a021
BindingDB Entry DOI: 10.7270/Q2DV1HXN
More data for this
Ligand-Target Pair