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9 similar compounds to monomer 50032094

Compile data set for download or QSAR
Wt: 250.2
BDBM50032130
Wt: 354.4
BDBM50032098
Wt: 340.4
BDBM50032137
Wt: 354.4
BDBM50032148
Wt: 326.3
BDBM50032149
Wt: 312.3
BDBM50089040
Purchase
Wt: 326.3
BDBM50089057
Wt: 383.4
BDBM50089065
Wt: 346.8
BDBM50089067

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50032130,50032098,50032137,50032148,50032149,50089040,50089057,50089065,50089067   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032098
PNG
(CHEMBL92508 | N*2*-Methyl-N*2*,N*4*-di-o-tolyl-qui...)
Show SMILES CN(c1ccccc1C)c1nc(Nc2ccccc2C)c2ccccc2n1
Show InChI InChI=1S/C23H22N4/c1-16-10-4-7-13-19(16)24-22-18-12-6-8-14-20(18)25-23(26-22)27(3)21-15-9-5-11-17(21)2/h4-15H,1-3H3,(H,24,25,26)
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n/an/a 2.00E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032130
PNG
(CHEMBL92471 | N*4*-Methyl-N*4*-phenyl-quinazoline-...)
Show SMILES CN(c1ccccc1)c1nc(N)nc2ccccc12
Show InChI InChI=1S/C15H14N4/c1-19(11-7-3-2-4-8-11)14-12-9-5-6-10-13(12)17-15(16)18-14/h2-10H,1H3,(H2,16,17,18)
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n/an/a 3.30E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032137
PNG
(CHEMBL92757 | N*4*-Methyl-N*4*-phenyl-N*2*-o-tolyl...)
Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2C)nc2ccccc12
Show InChI InChI=1S/C22H20N4/c1-16-10-6-8-14-19(16)23-22-24-20-15-9-7-13-18(20)21(25-22)26(2)17-11-4-3-5-12-17/h3-15H,1-2H3,(H,23,24,25)
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n/an/a 22n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032148
PNG
(CHEMBL329852 | N*4*-Methyl-N*2*,N*4*-di-o-tolyl-qu...)
Show SMILES CN(c1ccccc1C)c1nc(Nc2ccccc2C)nc2ccccc12
Show InChI InChI=1S/C23H22N4/c1-16-10-4-7-13-19(16)24-23-25-20-14-8-6-12-18(20)22(26-23)27(3)21-15-9-5-11-17(21)2/h4-15H,1-3H3,(H,24,25,26)
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n/an/a 46n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50089065
PNG
(CHEMBL279408 | N*2*-(4-Diethylamino-phenyl)-N*4*-p...)
Show SMILES CCN(CC)c1ccc(Nc2nc(Nc3ccccc3)c3ccccc3n2)cc1
Show InChI InChI=1S/C24H25N5/c1-3-29(4-2)20-16-14-19(15-17-20)26-24-27-22-13-9-8-12-21(22)23(28-24)25-18-10-6-5-7-11-18/h5-17H,3-4H2,1-2H3,(H2,25,26,27,28)
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n/an/a 4n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cells


Bioorg Med Chem Lett 10: 1175-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00177-3
BindingDB Entry DOI: 10.7270/Q2KH0MJP
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50089040
PNG
(CHEMBL17483 | N*2*,N*4*-Diphenyl-quinazoline-2,4-d...)
Show SMILES N(c1ccccc1)c1nc(Nc2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C20H16N4/c1-3-9-15(10-4-1)21-19-17-13-7-8-14-18(17)23-20(24-19)22-16-11-5-2-6-12-16/h1-14H,(H2,21,22,23,24)
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n/an/a 80n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cells


Bioorg Med Chem Lett 10: 1175-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00177-3
BindingDB Entry DOI: 10.7270/Q2KH0MJP
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50089057
PNG
(CHEMBL429053 | N*4*-Phenyl-N*2*-p-tolyl-quinazolin...)
Show SMILES Cc1ccc(Nc2nc(Nc3ccccc3)c3ccccc3n2)cc1
Show InChI InChI=1S/C21H18N4/c1-15-11-13-17(14-12-15)23-21-24-19-10-6-5-9-18(19)20(25-21)22-16-7-3-2-4-8-16/h2-14H,1H3,(H2,22,23,24,25)
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n/an/a 200n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cells


Bioorg Med Chem Lett 10: 1175-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00177-3
BindingDB Entry DOI: 10.7270/Q2KH0MJP
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50089067
PNG
(CHEMBL17326 | N*2*-(4-Chloro-phenyl)-N*4*-phenyl-q...)
Show SMILES Clc1ccc(Nc2nc(Nc3ccccc3)c3ccccc3n2)cc1
Show InChI InChI=1S/C20H15ClN4/c21-14-10-12-16(13-11-14)23-20-24-18-9-5-4-8-17(18)19(25-20)22-15-6-2-1-3-7-15/h1-13H,(H2,22,23,24,25)
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n/an/a 100n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cells


Bioorg Med Chem Lett 10: 1175-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00177-3
BindingDB Entry DOI: 10.7270/Q2KH0MJP
More data for this
Ligand-Target Pair
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032149
PNG
(CHEMBL330222 | N*4*-Methyl-N*2*,N*4*-diphenyl-quin...)
Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C21H18N4/c1-25(17-12-6-3-7-13-17)20-18-14-8-9-15-19(18)23-21(24-20)22-16-10-4-2-5-11-16/h2-15H,1H3,(H,22,23,24)
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n/an/a 65n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair