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1 similar compounds to monomer 22914

Compile data set for download or QSAR
Wt: 266.4
BDBM50033045

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033045   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50033045
PNG
(1-Cyclohexyl-3-[3-(1H-imidazol-4-yl)-propyl]-thiou...)
Show SMILES S=C(NCCCc1cnc[nH]1)NC1CCCCC1
Show InChI InChI=1S/C13H22N4S/c18-13(17-11-5-2-1-3-6-11)15-8-4-7-12-9-14-10-16-12/h9-11H,1-8H2,(H,14,16)(H2,15,17,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



University College London

Curated by ChEMBL


Assay Description
In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.


J Med Chem 38: 3342-50 (1995)


Article DOI: 10.1021/jm00017a018
BindingDB Entry DOI: 10.7270/Q2CN72X5
More data for this
Ligand-Target Pair
HRH3


(GUINEA PIG)
BDBM50033045
PNG
(1-Cyclohexyl-3-[3-(1H-imidazol-4-yl)-propyl]-thiou...)
Show SMILES S=C(NCCCc1cnc[nH]1)NC1CCCCC1
Show InChI InChI=1S/C13H22N4S/c18-13(17-11-5-2-1-3-6-11)15-8-4-7-12-9-14-10-16-12/h9-11H,1-8H2,(H,14,16)(H2,15,17,18)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 126n/an/an/an/an/a



Vrije Universiteit Amsterdam

Curated by ChEMBL


Assay Description
In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.


J Med Chem 38: 2244-50 (1995)


Article DOI: 10.1021/jm00012a025
BindingDB Entry DOI: 10.7270/Q2RF5W7Q
More data for this
Ligand-Target Pair