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26 similar compounds to monomer 50034083

Compile data set for download or QSAR
Wt: 318.4
BDBM50034101		Wt: 334.4
BDBM50045876		Wt: 334.4
BDBM50045857		Wt: 306.4
BDBM50045858		Wt: 304.3
BDBM50045862
Wt: 304.4
BDBM50095028		Wt: 264.3
BDBM50095029		Wt: 290.4
BDBM50095031		Wt: 276.3
BDBM50095032		Wt: 278.3
BDBM50095035
Wt: 292.4
BDBM50095040		Wt: 318.4
BDBM50095042Purchase		Wt: 318.4
BDBM50095047Purchase		Wt: 325.4
BDBM50034091		Wt: 309.8
BDBM50034106
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 70 hits for monomerid = 50034101,50045876,50045857,50045858,50045862,50095028,50095029,50095031,50095032,50095035,50095040,50095042,50095047,50034091,50034106   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095035
PNG
(CHEMBL91549 | Ethyl-methyl-[2-(2-phenyl-1H-indol-3...)
Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C19H22N2/c1-3-21(2)14-13-17-16-11-7-8-12-18(16)20-19(17)15-9-5-4-6-10-15/h4-12,20H,3,13-14H2,1-2H3
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 0.140n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095042
PNG
(3-[2-((R)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m1/s1
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 0.180n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 2.60n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 2.70n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-ketanserin from human 5-hydroxytryptamine 2A receptor expressed in CHO cells

Bioorg Med Chem Lett 10: 2701-3 (2000)


Article DOI: 10.1016/s0960-894x(00)00559-x
BindingDB Entry DOI: 10.7270/Q23J3C7W
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 2.70n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability of the compound to displace [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor was determined

Bioorg Med Chem Lett 10: 2693-6 (2000)


Article DOI: 10.1016/s0960-894x(00)00558-8
BindingDB Entry DOI: 10.7270/Q2C24VPJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095040
PNG
(CHEMBL328257 | Diethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CCN(CC)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H24N2/c1-3-22(4-2)15-14-18-17-12-8-9-13-19(17)21-20(18)16-10-6-5-7-11-16/h5-13,21H,3-4,14-15H2,1-2H3
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 2.80n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095047
PNG
(3-[2-((S)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m0/s1
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 4n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095029
PNG
(CHEMBL91447 | Dimethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C18H20N2/c1-20(2)13-12-16-15-10-6-7-11-17(15)19-18(16)14-8-4-3-5-9-14/h3-11,19H,12-13H2,1-2H3
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 4.40n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095031
PNG
(2-Phenyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | C...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H22N2/c1-2-8-16(9-3-1)20-18(12-15-22-13-6-7-14-22)17-10-4-5-11-19(17)21-20/h1-5,8-11,21H,6-7,12-15H2
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 9n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095035
PNG
(CHEMBL91549 | Ethyl-methyl-[2-(2-phenyl-1H-indol-3...)
Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C19H22N2/c1-3-21(2)14-13-17-16-11-7-8-12-18(16)20-19(17)15-9-5-4-6-10-15/h4-12,20H,3,13-14H2,1-2H3
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 11n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095042
PNG
(3-[2-((R)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m1/s1
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 21n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095042
PNG
(3-[2-((R)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m1/s1
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 36n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034106
PNG
(CHEMBL3359244)
Show SMILES Cc1nc(nc(OCCCN2CCCCC2)c1Cl)C1CC1
Show InChI InChI=1S/C16H24ClN3O/c1-12-14(17)16(19-15(18-12)13-6-7-13)21-11-5-10-20-8-3-2-4-9-20/h13H,2-11H2,1H3
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 40n/an/an/an/an/an/an/an/a



Huazhong University of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...

J Med Chem 57: 10404-23 (2014)


Article DOI: 10.1021/jm501207r
BindingDB Entry DOI: 10.7270/Q2XD138B
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50095032
PNG
(3-(2-Azetidin-1-yl-ethyl)-2-phenyl-1H-indole | CHE...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCC1
Show InChI InChI=1S/C19H20N2/c1-2-7-15(8-3-1)19-17(11-14-21-12-6-13-21)16-9-4-5-10-18(16)20-19/h1-5,7-10,20H,6,11-14H2
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 44n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095035
PNG
(CHEMBL91549 | Ethyl-methyl-[2-(2-phenyl-1H-indol-3...)
Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C19H22N2/c1-3-21(2)14-13-17-16-11-7-8-12-18(16)20-19(17)15-9-5-4-6-10-15/h4-12,20H,3,13-14H2,1-2H3
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 85n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
Melatonin receptor type 1B


(Homo sapiens (Human))		BDBM50034101
PNG
(CHEMBL14701 | Compound 6 | Cyclobutanecarboxylic a...)
Show SMILES O=C(NCCc1c([nH]c2ccccc12)-c1ccccc1)C1CCC1
Show InChI InChI=1S/C21H22N2O/c24-21(16-9-6-10-16)22-14-13-18-17-11-4-5-12-19(17)23-20(18)15-7-2-1-3-8-15/h1-5,7-8,11-12,16,23H,6,9-10,13-14H2,(H,22,24)
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 85.1n/an/an/an/an/an/an/an/a



Universit&agrove; degli Studi di Milano

Curated by PDSP Ki Database




Br J Pharmacol 127: 1288-94 (1999)


Article DOI: 10.1038/sj.bjp.0702658
BindingDB Entry DOI: 10.7270/Q20G3HQ6
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50045876
PNG
(CHEMBL329499 | N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-2-3-4-10-15-23-21(25)16-19-18-13-8-9-14-20(18)24-22(19)17-11-6-5-7-12-17/h5-9,11-14,24H,2-4,10,15-16H2,1H3,(H,23,25)
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 96n/an/an/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50045857
PNG
(2-(2-Phenyl-1H-indol-3-yl)-N,N-dipropyl-acetamide ...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-3-14-24(15-4-2)21(25)16-19-18-12-8-9-13-20(18)23-22(19)17-10-6-5-7-11-17/h5-13,23H,3-4,14-16H2,1-2H3
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 100n/an/an/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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 156n/an/an/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095040
PNG
(CHEMBL328257 | Diethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CCN(CC)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H24N2/c1-3-22(4-2)15-14-18-17-12-8-9-13-19(17)21-20(18)16-10-6-5-7-11-16/h5-13,21H,3-4,14-15H2,1-2H3
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 160n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095029
PNG
(CHEMBL91447 | Dimethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C18H20N2/c1-20(2)13-12-16-15-10-6-7-11-17(15)19-18(16)14-8-4-3-5-9-14/h3-11,19H,12-13H2,1-2H3
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 180n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
Melatonin receptor type 1A


(Homo sapiens (Human))		BDBM50034101
PNG
(CHEMBL14701 | Compound 6 | Cyclobutanecarboxylic a...)
Show SMILES O=C(NCCc1c([nH]c2ccccc12)-c1ccccc1)C1CCC1
Show InChI InChI=1S/C21H22N2O/c24-21(16-9-6-10-16)22-14-13-18-17-11-4-5-12-19(17)23-20(18)15-7-2-1-3-8-15/h1-5,7-8,11-12,16,23H,6,9-10,13-14H2,(H,22,24)
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 200n/an/an/an/an/an/an/an/a



Universita degli Studi di Milano

Curated by PDSP Ki Database




J Med Chem 41: 3624-34 (1998)


Article DOI: 10.1021/jm970721h
BindingDB Entry DOI: 10.7270/Q2T43RN6
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095047
PNG
(3-[2-((S)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m0/s1
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 230n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095031
PNG
(2-Phenyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | C...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H22N2/c1-2-8-16(9-3-1)20-18(12-15-22-13-6-7-14-22)17-10-4-5-11-19(17)21-20/h1-5,8-11,21H,6-7,12-15H2
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 260n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 268n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095047
PNG
(3-[2-((S)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl...)
Show SMILES C[C@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m0/s1
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 290n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034091
PNG
(CHEMBL3358645)
Show SMILES Cc1cc(OCCCN2CCC(=O)CC2)nc(n1)-c1ccccc1
Show InChI InChI=1S/C19H23N3O2/c1-15-14-18(21-19(20-15)16-6-3-2-4-7-16)24-13-5-10-22-11-8-17(23)9-12-22/h2-4,6-7,14H,5,8-13H2,1H3
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 319n/an/an/an/an/an/an/an/a



Huazhong University of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...

J Med Chem 57: 10404-23 (2014)


Article DOI: 10.1021/jm501207r
BindingDB Entry DOI: 10.7270/Q2XD138B
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50045862
PNG
(2-(2-Phenyl-1H-indol-3-yl)-1-pyrrolidin-1-yl-ethan...)
Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H20N2O/c23-19(22-12-6-7-13-22)14-17-16-10-4-5-11-18(16)21-20(17)15-8-2-1-3-9-15/h1-5,8-11,21H,6-7,12-14H2
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 338n/an/an/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Melatonin receptor type 1C


(Gallus gallus)		BDBM50034101
PNG
(CHEMBL14701 | Compound 6 | Cyclobutanecarboxylic a...)
Show SMILES O=C(NCCc1c([nH]c2ccccc12)-c1ccccc1)C1CCC1
Show InChI InChI=1S/C21H22N2O/c24-21(16-9-6-10-16)22-14-13-18-17-11-4-5-12-19(17)23-20(18)15-7-2-1-3-8-15/h1-5,7-8,11-12,16,23H,6,9-10,13-14H2,(H,22,24)
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 565n/an/an/an/an/an/an/an/a



University College London

Curated by ChEMBL


Assay Description
Binding affinity in chicken brain membranes by using [2-125I]melatonin in a competition radioligand binding assay

J Med Chem 38: 1132-9 (1995)


Article DOI: 10.1021/jm00007a010
BindingDB Entry DOI: 10.7270/Q2HM5C6M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 896n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095028
PNG
(2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CH...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1
Show InChI InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2
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 900n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability of the compound to displace [3H]-spiperone from CHO cells expressing human Dopamine receptor D2 was determined

Bioorg Med Chem Lett 10: 2693-6 (2000)


Article DOI: 10.1016/s0960-894x(00)00558-8
BindingDB Entry DOI: 10.7270/Q2C24VPJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50095032
PNG
(3-(2-Azetidin-1-yl-ethyl)-2-phenyl-1H-indole | CHE...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCC1
Show InChI InChI=1S/C19H20N2/c1-2-7-15(8-3-1)19-17(11-14-21-12-6-13-21)16-9-4-5-10-18(16)20-19/h1-5,7-10,20H,6,11-14H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095031
PNG
(2-Phenyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | C...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H22N2/c1-2-8-16(9-3-1)20-18(12-15-22-13-6-7-14-22)17-10-4-5-11-19(17)21-20/h1-5,8-11,21H,6-7,12-15H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095032
PNG
(3-(2-Azetidin-1-yl-ethyl)-2-phenyl-1H-indole | CHE...)
Show SMILES C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCC1
Show InChI InChI=1S/C19H20N2/c1-2-7-15(8-3-1)19-17(11-14-21-12-6-13-21)16-9-4-5-10-18(16)20-19/h1-5,7-10,20H,6,11-14H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095029
PNG
(CHEMBL91447 | Dimethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CN(C)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C18H20N2/c1-20(2)13-12-16-15-10-6-7-11-17(15)19-18(16)14-8-4-3-5-9-14/h3-11,19H,12-13H2,1-2H3
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>1.00E+3n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50095040
PNG
(CHEMBL328257 | Diethyl-[2-(2-phenyl-1H-indol-3-yl)...)
Show SMILES CCN(CC)CCc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H24N2/c1-3-22(4-2)15-14-18-17-12-8-9-13-19(17)21-20(18)16-10-6-5-7-11-16/h5-13,21H,3-4,14-15H2,1-2H3
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>1.00E+3n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.

Bioorg Med Chem Lett 10: 2697-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00557-6
BindingDB Entry DOI: 10.7270/Q27943XR
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))		BDBM50034101
PNG
(CHEMBL14701 | Compound 6 | Cyclobutanecarboxylic a...)
Show SMILES O=C(NCCc1c([nH]c2ccccc12)-c1ccccc1)C1CCC1
Show InChI InChI=1S/C21H22N2O/c24-21(16-9-6-10-16)22-14-13-18-17-11-4-5-12-19(17)23-20(18)15-7-2-1-3-8-15/h1-5,7-8,11-12,16,23H,6,9-10,13-14H2,(H,22,24)
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 1.90E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligand

J Med Chem 40: 1990-2002 (1997)


Article DOI: 10.1021/jm960651z
BindingDB Entry DOI: 10.7270/Q2HD7ZCK
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibition of [3H]naxolone binding to opiate receptors in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)		BDBM50045862
PNG
(2-(2-Phenyl-1H-indol-3-yl)-1-pyrrolidin-1-yl-ethan...)
Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H20N2O/c23-19(22-12-6-7-13-22)14-17-16-10-4-5-11-18(16)21-20(17)15-8-2-1-3-9-15/h1-5,8-11,21H,6-7,12-14H2
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)		BDBM50045876
PNG
(CHEMBL329499 | N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-2-3-4-10-15-23-21(25)16-19-18-13-8-9-14-20(18)24-22(19)17-11-6-5-7-12-17/h5-9,11-14,24H,2-4,10,15-16H2,1H3,(H,23,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)		BDBM50045857
PNG
(2-(2-Phenyl-1H-indol-3-yl)-N,N-dipropyl-acetamide ...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-3-14-24(15-4-2)21(25)16-19-18-12-8-9-13-20(18)23-22(19)17-10-6-5-7-11-17/h5-13,23H,3-4,14-16H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)		BDBM50045862
PNG
(2-(2-Phenyl-1H-indol-3-yl)-1-pyrrolidin-1-yl-ethan...)
Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1
Show InChI InChI=1S/C20H20N2O/c23-19(22-12-6-7-13-22)14-17-16-10-4-5-11-18(16)21-20(17)15-8-2-1-3-9-15/h1-5,8-11,21H,6-7,12-14H2
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))		BDBM50045857
PNG
(2-(2-Phenyl-1H-indol-3-yl)-N,N-dipropyl-acetamide ...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-3-14-24(15-4-2)21(25)16-19-18-12-8-9-13-20(18)23-22(19)17-10-6-5-7-11-17/h5-13,23H,3-4,14-16H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))		BDBM50045876
PNG
(CHEMBL329499 | N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-2-3-4-10-15-23-21(25)16-19-18-13-8-9-14-20(18)24-22(19)17-11-6-5-7-12-17/h5-9,11-14,24H,2-4,10,15-16H2,1H3,(H,23,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))		BDBM50045858
PNG
(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Show SMILES CCN(CC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O/c1-3-22(4-2)19(23)14-17-16-12-8-9-13-18(16)21-20(17)15-10-6-5-7-11-15/h5-13,21H,3-4,14H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)		BDBM50045857
PNG
(2-(2-Phenyl-1H-indol-3-yl)-N,N-dipropyl-acetamide ...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-3-14-24(15-4-2)21(25)16-19-18-12-8-9-13-20(18)23-22(19)17-10-6-5-7-11-17/h5-13,23H,3-4,14-16H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)		BDBM50045876
PNG
(CHEMBL329499 | N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H26N2O/c1-2-3-4-10-15-23-21(25)16-19-18-13-8-9-14-20(18)24-22(19)17-11-6-5-7-12-17/h5-9,11-14,24H,2-4,10,15-16H2,1H3,(H,23,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation

Curated by ChEMBL


Assay Description
Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain

J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
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