BindingDB logo
myBDB logout

4 similar compounds to monomer 50385148

Compile data set for download or QSAR
Wt: 328.4
BDBM50034285
Wt: 342.4
BDBM50034287
Wt: 342.4
BDBM50034288
Wt: 356.4
BDBM50034306

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50034285,50034287,50034288,50034306   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034288
PNG
(1-Methyl-1H-pyrrole-2-carboxylic acid {2-[4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccn2C)CC1
Show InChI InChI=1S/C19H26N4O2/c1-21-10-5-7-17(21)19(24)20-9-11-22-12-14-23(15-13-22)16-6-3-4-8-18(16)25-2/h3-8,10H,9,11-15H2,1-2H3,(H,20,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.19n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034306
PNG
(1H-Pyrrole-2-carboxylic acid {4-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C20H28N4O2/c1-26-19-9-3-2-8-18(19)24-15-13-23(14-16-24)12-5-4-10-22-20(25)17-7-6-11-21-17/h2-3,6-9,11,21H,4-5,10,12-16H2,1H3,(H,22,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12.5n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034285
PNG
(1H-Pyrrole-2-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C18H24N4O2/c1-24-17-7-3-2-6-16(17)22-13-11-21(12-14-22)10-9-20-18(23)15-5-4-8-19-15/h2-8,19H,9-14H2,1H3,(H,20,23)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034285
PNG
(1H-Pyrrole-2-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C18H24N4O2/c1-24-17-7-3-2-6-16(17)22-13-11-21(12-14-22)10-9-20-18(23)15-5-4-8-19-15/h2-8,19H,9-14H2,1H3,(H,20,23)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20.3n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034285
PNG
(1H-Pyrrole-2-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C18H24N4O2/c1-24-17-7-3-2-6-16(17)22-13-11-21(12-14-22)10-9-20-18(23)15-5-4-8-19-15/h2-8,19H,9-14H2,1H3,(H,20,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
64n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034287
PNG
(1H-Pyrrole-2-carboxylic acid {3-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C19H26N4O2/c1-25-18-8-3-2-7-17(18)23-14-12-22(13-15-23)11-5-10-21-19(24)16-6-4-9-20-16/h2-4,6-9,20H,5,10-15H2,1H3,(H,21,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
201n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair