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26 similar compounds to monomer 50034886

Compile data set for download or QSAR
Wt: 468.5
BDBM50034813
Wt: 506.4
BDBM50034814
Wt: 482.5
BDBM50034819
Wt: 495.5
BDBM50034825
Wt: 468.5
BDBM50034836
Wt: 517.3
BDBM50034876
Wt: 468.5
BDBM50034879
Wt: 456.4
BDBM50034880
Wt: 456.4
BDBM50034881
Wt: 468.5
BDBM50034883
Wt: 495.5
BDBM50034884
Wt: 468.5
BDBM50034887
Wt: 522.4
BDBM50034888
Wt: 452.5
BDBM50034889
Wt: 452.5
BDBM50034890
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50034813,50034814,50034819,50034825,50034836,50034876,50034879,50034880,50034881,50034883,50034884,50034887,50034888,50034889,50034890   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034813
PNG
(CHEMBL3338091)
Show SMILES COc1cccc(Cc2c(C)n(CC(O)=O)c3CCNC(=O)c23)c1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H24N2O6S/c1-15-18(22-19(11-12-25-24(22)29)26(15)14-21(27)28)13-16-7-6-10-20(32-2)23(16)33(30,31)17-8-4-3-5-9-17/h3-10H,11-14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 20n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034890
PNG
(CHEMBL3338111)
Show SMILES C[C@H](C(O)=O)n1c(C)c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c1CCNC2=O
Show InChI InChI=1/C24H24N2O5S/c1-15-19(22-20(12-13-25-23(22)27)26(15)16(2)24(28)29)14-17-8-6-7-11-21(17)32(30,31)18-9-4-3-5-10-18/h3-11,16H,12-14H2,1-2H3,(H,25,27)(H,28,29)/t16-/s2
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n/an/a 430n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034819
PNG
(CHEMBL3338093)
Show SMILES Cc1c(Cc2ccc(cc2S(=O)(=O)c2ccccc2)C(O)=O)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C24H22N2O7S/c1-14-18(22-19(9-10-25-23(22)29)26(14)13-21(27)28)11-15-7-8-16(24(30)31)12-20(15)34(32,33)17-5-3-2-4-6-17/h2-8,12H,9-11,13H2,1H3,(H,25,29)(H,27,28)(H,30,31)
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n/an/a 19n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034825
PNG
(CHEMBL3338095)
Show SMILES CNC(=O)c1ccc(Cc2c(C)n(CC(O)=O)c3CCNC(=O)c23)c(c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H25N3O6S/c1-15-19(23-20(10-11-27-25(23)32)28(15)14-22(29)30)12-16-8-9-17(24(31)26-2)13-21(16)35(33,34)18-6-4-3-5-7-18/h3-9,13H,10-12,14H2,1-2H3,(H,26,31)(H,27,32)(H,29,30)
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n/an/a 10n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034836
PNG
(CHEMBL3338097)
Show SMILES COc1ccc(c(Cc2c(C)n(CC(O)=O)c3CCNC(=O)c23)c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H24N2O6S/c1-15-19(23-20(10-11-25-24(23)29)26(15)14-22(27)28)13-16-12-17(32-2)8-9-21(16)33(30,31)18-6-4-3-5-7-18/h3-9,12H,10-11,13-14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 3.60n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034876
PNG
(CHEMBL3338098)
Show SMILES Cc1c(Cc2cc(Br)ccc2S(=O)(=O)c2ccccc2)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C23H21BrN2O5S/c1-14-18(22-19(9-10-25-23(22)29)26(14)13-21(27)28)12-15-11-16(24)7-8-20(15)32(30,31)17-5-3-2-4-6-17/h2-8,11H,9-10,12-13H2,1H3,(H,25,29)(H,27,28)
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n/an/a 3.90n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034879
PNG
(CHEMBL3338100)
Show SMILES COc1cccc(c1Cc1c(C)n(CC(O)=O)c2CCNC(=O)c12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H24N2O6S/c1-15-17(23-19(11-12-25-24(23)29)26(15)14-22(27)28)13-18-20(32-2)9-6-10-21(18)33(30,31)16-7-4-3-5-8-16/h3-10H,11-14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 4.50E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034880
PNG
(CHEMBL3338101)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2F)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C23H21FN2O5S/c1-14-16(22-18(10-11-25-23(22)29)26(14)13-21(27)28)12-15-6-2-4-8-19(15)32(30,31)20-9-5-3-7-17(20)24/h2-9H,10-13H2,1H3,(H,25,29)(H,27,28)
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n/an/a 3.60n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034881
PNG
(CHEMBL3338102)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2cccc(F)c2)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C23H21FN2O5S/c1-14-18(22-19(9-10-25-23(22)29)26(14)13-21(27)28)11-15-5-2-3-8-20(15)32(30,31)17-7-4-6-16(24)12-17/h2-8,12H,9-11,13H2,1H3,(H,25,29)(H,27,28)
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n/an/a 6.20n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034883
PNG
(CHEMBL3337462)
Show SMILES COc1cccc(c1)S(=O)(=O)c1ccccc1Cc1c(C)n(CC(O)=O)c2CCNC(=O)c12
Show InChI InChI=1S/C24H24N2O6S/c1-15-19(23-20(10-11-25-24(23)29)26(15)14-22(27)28)12-16-6-3-4-9-21(16)33(30,31)18-8-5-7-17(13-18)32-2/h3-9,13H,10-12,14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 12n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034884
PNG
(CHEMBL3338104)
Show SMILES CNC(=O)c1cccc(c1)S(=O)(=O)c1ccccc1Cc1c(C)n(CC(O)=O)c2CCNC(=O)c12
Show InChI InChI=1S/C25H25N3O6S/c1-15-19(23-20(10-11-27-25(23)32)28(15)14-22(29)30)13-16-6-3-4-9-21(16)35(33,34)18-8-5-7-17(12-18)24(31)26-2/h3-9,12H,10-11,13-14H2,1-2H3,(H,26,31)(H,27,32)(H,29,30)
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n/an/a 240n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034887
PNG
(CHEMBL3338107)
Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1Cc1c(C)n(CC(O)=O)c2CCNC(=O)c12
Show InChI InChI=1S/C24H24N2O6S/c1-15-19(23-20(11-12-25-24(23)29)26(15)14-22(27)28)13-16-5-3-4-6-21(16)33(30,31)18-9-7-17(32-2)8-10-18/h3-10H,11-14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 3.90n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034888
PNG
(CHEMBL3338108)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(OC(F)(F)F)cc2)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C24H21F3N2O6S/c1-14-18(22-19(10-11-28-23(22)32)29(14)13-21(30)31)12-15-4-2-3-5-20(15)36(33,34)17-8-6-16(7-9-17)35-24(25,26)27/h2-9H,10-13H2,1H3,(H,28,32)(H,30,31)
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n/an/a 6.60n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034889
PNG
(CHEMBL3338110)
Show SMILES C[C@@H](C(O)=O)n1c(C)c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c1CCNC2=O
Show InChI InChI=1/C24H24N2O5S/c1-15-19(22-20(12-13-25-23(22)27)26(15)16(2)24(28)29)14-17-8-6-7-11-21(17)32(30,31)18-9-4-3-5-10-18/h3-11,16H,12-14H2,1-2H3,(H,25,27)(H,28,29)/t16-/s2
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n/an/a 91n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034814
PNG
(CHEMBL3338092)
Show SMILES Cc1c(Cc2ccc(cc2S(=O)(=O)c2ccccc2)C(F)(F)F)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C24H21F3N2O5S/c1-14-18(22-19(9-10-28-23(22)32)29(14)13-21(30)31)11-15-7-8-16(24(25,26)27)12-20(15)35(33,34)17-5-3-2-4-6-17/h2-8,12H,9-11,13H2,1H3,(H,28,32)(H,30,31)
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n/an/a 13n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair