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69 similar compounds to monomer 50165819

Compile data set for download or QSAR
Wt: 453.4
BDBM50165805
Wt: 443.4
BDBM50165806
Wt: 396.4
BDBM50165807
Wt: 444.4
BDBM50165808
Wt: 437.4
BDBM50165809
Wt: 467.5
BDBM50165810
Wt: 423.5
BDBM50165811
Wt: 424.4
BDBM50165812
Wt: 396.4
BDBM50165813
Wt: 444.4
BDBM50165814
Wt: 382.4
BDBM50165815
Wt: 439.4
BDBM50165816
Wt: 458.5
BDBM50165817
Wt: 457.5
BDBM50165818
Wt: 425.4
BDBM50165820
Displayed 1 to 15 (of 69 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50165805,50165806,50165807,50165808,50165809,50165810,50165811,50165812,50165813,50165814,50165815,50165816,50165817,50165818,50165820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165805
PNG
(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C26H23N5O3/c1-17-24-21-15-20(19-11-6-3-7-12-19)29-31(21)22(13-8-14-23(32)33)27-25(24)26(34)30(28-17)16-18-9-4-2-5-10-18/h2-7,9-12,15H,8,13-14,16H2,1H3,(H,32,33)
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n/an/a 30n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165810
PNG
(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C27H25N5O3/c1-18-25-22-16-21(20-12-6-3-7-13-20)30-32(22)23(14-8-9-15-24(33)34)28-26(25)27(35)31(29-18)17-19-10-4-2-5-11-19/h2-7,10-13,16H,8-9,14-15,17H2,1H3,(H,33,34)
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n/an/a 63n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165811
PNG
(7-Benzyl-4-sec-butyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Show SMILES CCC(C)c1nc2c(c(C)nn(Cc3ccccc3)c2=O)c2cc(nn12)-c1ccccc1
Show InChI InChI=1S/C26H25N5O/c1-4-17(2)25-27-24-23(22-15-21(29-31(22)25)20-13-9-6-10-14-20)18(3)28-30(26(24)32)16-19-11-7-5-8-12-19/h5-15,17H,4,16H2,1-3H3
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n/an/a 34n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165809
PNG
((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(\C=C\C(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C25H19N5O3/c1-16-23-20-14-19(18-10-6-3-7-11-18)28-30(20)21(12-13-22(31)32)26-24(23)25(33)29(27-16)15-17-8-4-2-5-9-17/h2-14H,15H2,1H3,(H,31,32)/b13-12+
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n/an/a 320n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165815
PNG
(7-Benzyl-4,9-dimethyl-2-pyridin-2-yl-7H-3,3a,5,7,8...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccccn1
Show InChI InChI=1S/C22H18N6O/c1-14-20-19-12-18(17-10-6-7-11-23-17)26-28(19)15(2)24-21(20)22(29)27(25-14)13-16-8-4-3-5-9-16/h3-12H,13H2,1-2H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165820
PNG
(2-Benzo[1,3]dioxol-5-yl-7-benzyl-4,9-dimethyl-7H-3...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C24H19N5O3/c1-14-22-19-11-18(17-8-9-20-21(10-17)32-13-31-20)27-29(19)15(2)25-23(22)24(30)28(26-14)12-16-6-4-3-5-7-16/h3-11H,12-13H2,1-2H3
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n/an/a 1.30E+4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165807
PNG
(7-(4-Amino-benzyl)-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Show SMILES Cc1nn(Cc2ccc(N)cc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C23H20N6O/c1-14-21-20-12-19(17-6-4-3-5-7-17)27-29(20)15(2)25-22(21)23(30)28(26-14)13-16-8-10-18(24)11-9-16/h3-12H,13,24H2,1-2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165812
PNG
(7-Benzyl-4-sec-butyl-9-methyl-2-pyridin-2-yl-7H-3,...)
Show SMILES CCC(C)c1nc2c(c(C)nn(Cc3ccccc3)c2=O)c2cc(nn12)-c1ccccn1
Show InChI InChI=1S/C25H24N6O/c1-4-16(2)24-27-23-22(21-14-20(29-31(21)24)19-12-8-9-13-26-19)17(3)28-30(25(23)32)15-18-10-6-5-7-11-18/h5-14,16H,4,15H2,1-3H3
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n/an/a 39n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165809
PNG
((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(\C=C\C(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C25H19N5O3/c1-16-23-20-14-19(18-10-6-3-7-11-18)28-30(20)21(12-13-22(31)32)26-24(23)25(33)29(27-16)15-17-8-4-2-5-9-17/h2-14H,15H2,1H3,(H,31,32)/b13-12+
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n/an/a 580n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165815
PNG
(7-Benzyl-4,9-dimethyl-2-pyridin-2-yl-7H-3,3a,5,7,8...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccccn1
Show InChI InChI=1S/C22H18N6O/c1-14-20-19-12-18(17-10-6-7-11-23-17)26-28(19)15(2)24-21(20)22(29)27(25-14)13-16-8-4-3-5-9-16/h3-12H,13H2,1-2H3
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n/an/a 270n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165820
PNG
(2-Benzo[1,3]dioxol-5-yl-7-benzyl-4,9-dimethyl-7H-3...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C24H19N5O3/c1-14-22-19-11-18(17-8-9-20-21(10-17)32-13-31-20)27-29(19)15(2)25-23(22)24(30)28(26-14)12-16-6-4-3-5-7-16/h3-11H,12-13H2,1-2H3
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n/an/a 7.80E+4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165816
PNG
(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C25H21N5O3/c1-16-23-20-14-19(18-10-6-3-7-11-18)28-30(20)21(12-13-22(31)32)26-24(23)25(33)29(27-16)15-17-8-4-2-5-9-17/h2-11,14H,12-13,15H2,1H3,(H,31,32)
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n/an/a 430n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165805
PNG
(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C26H23N5O3/c1-17-24-21-15-20(19-11-6-3-7-12-19)29-31(21)22(13-8-14-23(32)33)27-25(24)26(34)30(28-17)16-18-9-4-2-5-10-18/h2-7,9-12,15H,8,13-14,16H2,1H3,(H,32,33)
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n/an/a 110n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165813
PNG
(2-(4-Amino-phenyl)-7-benzyl-4,9-dimethyl-7H-3,3a,5...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccc(N)cc1
Show InChI InChI=1S/C23H20N6O/c1-14-21-20-12-19(17-8-10-18(24)11-9-17)27-29(20)15(2)25-22(21)23(30)28(26-14)13-16-6-4-3-5-7-16/h3-12H,13,24H2,1-2H3
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n/an/a 920n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165807
PNG
(7-(4-Amino-benzyl)-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Show SMILES Cc1nn(Cc2ccc(N)cc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C23H20N6O/c1-14-21-20-12-19(17-6-4-3-5-7-17)27-29(20)15(2)25-22(21)23(30)28(26-14)13-16-8-10-18(24)11-9-16/h3-12H,13,24H2,1-2H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165817
PNG
(7-Benzyl-9-methyl-2-phenyl-4-pyridin-4-ylmethyl-7H...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(Cc3ccncc3)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C28H22N6O/c1-19-26-24-17-23(22-10-6-3-7-11-22)32-34(24)25(16-20-12-14-29-15-13-20)30-27(26)28(35)33(31-19)18-21-8-4-2-5-9-21/h2-15,17H,16,18H2,1H3
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n/an/a 450n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165806
PNG
(7-Benzyl-9-methyl-2,4-diphenyl-7H-3,3a,5,7,8-penta...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(-c3ccccc3)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C28H21N5O/c1-19-25-24-17-23(21-13-7-3-8-14-21)31-33(24)27(22-15-9-4-10-16-22)29-26(25)28(34)32(30-19)18-20-11-5-2-6-12-20/h2-17H,18H2,1H3
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n/an/a 2.80E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165814
PNG
(7-Benzyl-9-methyl-2-phenyl-4-pyridin-2-yl-7H-3,3a,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(-c3ccccn3)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C27H20N6O/c1-18-24-23-16-22(20-12-6-3-7-13-20)31-33(23)26(21-14-8-9-15-28-21)29-25(24)27(34)32(30-18)17-19-10-4-2-5-11-19/h2-16H,17H2,1H3
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n/an/a 81n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165810
PNG
(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C27H25N5O3/c1-18-25-22-16-21(20-12-6-3-7-13-20)30-32(22)23(14-8-9-15-24(33)34)28-26(25)27(35)31(29-18)17-19-10-4-2-5-11-19/h2-7,10-13,16H,8-9,14-15,17H2,1H3,(H,33,34)
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n/an/a 90n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165806
PNG
(7-Benzyl-9-methyl-2,4-diphenyl-7H-3,3a,5,7,8-penta...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(-c3ccccc3)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C28H21N5O/c1-19-25-24-17-23(21-13-7-3-8-14-21)31-33(24)27(22-15-9-4-10-16-22)29-26(25)28(34)32(30-19)18-20-11-5-2-6-12-20/h2-17H,18H2,1H3
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n/an/a 81n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165808
PNG
(7-Benzyl-9-methyl-2-phenyl-4-pyridin-3-yl-7H-3,3a,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(-c3cccnc3)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C27H20N6O/c1-18-24-23-15-22(20-11-6-3-7-12-20)31-33(23)26(21-13-8-14-28-16-21)29-25(24)27(34)32(30-18)17-19-9-4-2-5-10-19/h2-16H,17H2,1H3
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n/an/a 180n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50165818
PNG
(7-Benzyl-9-methyl-2-phenyl-4-m-tolyl-7H-3,3a,5,7,8...)
Show SMILES Cc1cccc(c1)-c1nc2c(c(C)nn(Cc3ccccc3)c2=O)c2cc(nn12)-c1ccccc1
Show InChI InChI=1S/C29H23N5O/c1-19-10-9-15-23(16-19)28-30-27-26(25-17-24(32-34(25)28)22-13-7-4-8-14-22)20(2)31-33(29(27)35)18-21-11-5-3-6-12-21/h3-17H,18H2,1-2H3
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n/an/a 75n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 5 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair
Phosphodiesterase 6


(Bos taurus-Bos taurus (Bovine))
BDBM50165816
PNG
(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCC(O)=O)n3nc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C25H21N5O3/c1-16-23-20-14-19(18-10-6-3-7-11-18)28-30(20)21(12-13-22(31)32)26-24(23)25(33)29(27-16)15-17-8-4-2-5-9-17/h2-11,14H,12-13,15H2,1H3,(H,31,32)
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n/an/a 590n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of bovine Phosphodiesterase 6 (n=2-3)


Bioorg Med Chem Lett 15: 2381-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.090
BindingDB Entry DOI: 10.7270/Q2K64HK9
More data for this
Ligand-Target Pair