BindingDB logo
myBDB logout

14 similar compounds to monomer 50042891

Wt: 291.3
BDBM50042898
Wt: 377.4
BDBM50042883
Wt: 377.4
BDBM50042886
Wt: 363.4
BDBM50042887
Wt: 361.4
BDBM50042888
Wt: 335.4
BDBM50042892
Wt: 319.4
BDBM50042893
Wt: 307.4
BDBM50042896
Wt: 305.4
BDBM50042897
Wt: 319.4
BDBM50042585
Wt: 305.4
BDBM50042599
Wt: 291.3
BDBM50042648
Wt: 321.4
BDBM50042657
Wt: 335.4
BDBM50042658

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50042898,50042883,50042886,50042887,50042888,50042892,50042893,50042896,50042897,50042585,50042599,50042648,50042657,50042658   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042658
PNG
(CHEMBL3353869)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CCOCC2)no1
Show InChI InChI=1/C18H29N3O3/c1-18(2,3)15-11-16(20-24-15)19-17(22)14-5-4-8-21(14)12-13-6-9-23-10-7-13/h11,13-14H,4-10,12H2,1-3H3,(H,19,20,22)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.10n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042658
PNG
(CHEMBL3353869)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CCOCC2)no1
Show InChI InChI=1/C18H29N3O3/c1-18(2,3)15-11-16(20-24-15)19-17(22)14-5-4-8-21(14)12-13-6-9-23-10-7-13/h11,13-14H,4-10,12H2,1-3H3,(H,19,20,22)/t14-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.90E+3n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042648
PNG
(CHEMBL3353867)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CC2)no1
Show InChI InChI=1/C16H25N3O2/c1-16(2,3)13-9-14(18-21-13)17-15(20)12-5-4-8-19(12)10-11-6-7-11/h9,11-12H,4-8,10H2,1-3H3,(H,17,18,20)/t12-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 7.70n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042599
PNG
(CHEMBL3353865)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCC2)no1
Show InChI InChI=1/C17H27N3O2/c1-17(2,3)14-11-15(19-22-14)18-16(21)13-9-6-10-20(13)12-7-4-5-8-12/h11-13H,4-10H2,1-3H3,(H,18,19,21)/t13-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.20n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042883
PNG
(CHEMBL3354545)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)CC2CCOCC2)no1
Show InChI InChI=1/C20H31N3O4/c1-20(2,3)16-13-17(22-27-16)21-19(25)15-6-4-5-9-23(15)18(24)12-14-7-10-26-11-8-14/h13-15H,4-12H2,1-3H3,(H,21,22,25)/t15-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.98E+3n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042886
PNG
(CHEMBL3354542)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)[C@H]2CC[C@H](O)CC2)no1
Show InChI InChI=1/C20H31N3O4/c1-20(2,3)16-12-17(22-27-16)21-18(25)15-6-4-5-11-23(15)19(26)13-7-9-14(24)10-8-13/h12-15,24H,4-11H2,1-3H3,(H,21,22,25)/t13-,14-,15-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042887
PNG
(CHEMBL3354541)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)C2CCOCC2)no1
Show InChI InChI=1/C19H29N3O4/c1-19(2,3)15-12-16(21-26-15)20-17(23)14-6-4-5-9-22(14)18(24)13-7-10-25-11-8-13/h12-14H,4-11H2,1-3H3,(H,20,21,23)/t14-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042888
PNG
(CHEMBL3354540)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)C2CCCCC2)no1
Show InChI InChI=1/C20H31N3O3/c1-20(2,3)16-13-17(22-26-16)21-18(24)15-11-7-8-12-23(15)19(25)14-9-5-4-6-10-14/h13-15H,4-12H2,1-3H3,(H,21,22,24)/t15-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.76E+3n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042892
PNG
(CHEMBL3354534)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CCOCC2)no1
Show InChI InChI=1/C18H29N3O3/c1-18(2,3)15-12-16(20-24-15)19-17(22)14-6-4-5-9-21(14)13-7-10-23-11-8-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042893
PNG
(CHEMBL3354533)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CCCC2)no1
Show InChI InChI=1/C18H29N3O2/c1-18(2,3)15-12-16(20-23-15)19-17(22)14-10-6-7-11-21(14)13-8-4-5-9-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.30E+4n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042896
PNG
(CHEMBL3354532)
Show SMILES CC(C)CN1CCCC[C@H]1C(=O)Nc1cc(on1)C(C)(C)C
Show InChI InChI=1/C17H29N3O2/c1-12(2)11-20-9-7-6-8-13(20)16(21)18-15-10-14(22-19-15)17(3,4)5/h10,12-13H,6-9,11H2,1-5H3,(H,18,19,21)/t13-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.97E+3n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042897
PNG
(CHEMBL3354531)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2CC2CC2)no1
Show InChI InChI=1/C17H27N3O2/c1-17(2,3)14-10-15(19-22-14)18-16(21)13-6-4-5-9-20(13)11-12-7-8-12/h10,12-13H,4-9,11H2,1-3H3,(H,18,19,21)/t13-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.94E+3n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042898
PNG
(CHEMBL3354530)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CC2)no1
Show InChI InChI=1/C16H25N3O2/c1-16(2,3)13-10-14(18-21-13)17-15(20)12-6-4-5-9-19(12)11-7-8-11/h10-12H,4-9H2,1-3H3,(H,17,18,20)/t12-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042883
PNG
(CHEMBL3354545)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)CC2CCOCC2)no1
Show InChI InChI=1/C20H31N3O4/c1-20(2,3)16-13-17(22-27-16)21-19(25)15-6-4-5-9-23(15)18(24)12-14-7-10-26-11-8-14/h13-15H,4-12H2,1-3H3,(H,21,22,25)/t15-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 18n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042886
PNG
(CHEMBL3354542)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)[C@H]2CC[C@H](O)CC2)no1
Show InChI InChI=1/C20H31N3O4/c1-20(2,3)16-12-17(22-27-16)21-18(25)15-6-4-5-11-23(15)19(26)13-7-9-14(24)10-8-13/h12-15,24H,4-11H2,1-3H3,(H,21,22,25)/t13-,14-,15-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 41n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042887
PNG
(CHEMBL3354541)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)C2CCOCC2)no1
Show InChI InChI=1/C19H29N3O4/c1-19(2,3)15-12-16(21-26-15)20-17(23)14-6-4-5-9-22(14)18(24)13-7-10-25-11-8-13/h12-14H,4-11H2,1-3H3,(H,20,21,23)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 111n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042888
PNG
(CHEMBL3354540)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)C2CCCCC2)no1
Show InChI InChI=1/C20H31N3O3/c1-20(2,3)16-13-17(22-26-16)21-18(24)15-11-7-8-12-23(15)19(25)14-9-5-4-6-10-14/h13-15H,4-12H2,1-3H3,(H,21,22,24)/t15-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 15n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042892
PNG
(CHEMBL3354534)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CCOCC2)no1
Show InChI InChI=1/C18H29N3O3/c1-18(2,3)15-12-16(20-24-15)19-17(22)14-6-4-5-9-21(14)13-7-10-23-11-8-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 33n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042893
PNG
(CHEMBL3354533)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CCCC2)no1
Show InChI InChI=1/C18H29N3O2/c1-18(2,3)15-12-16(20-23-15)19-17(22)14-10-6-7-11-21(14)13-8-4-5-9-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 14n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042896
PNG
(CHEMBL3354532)
Show SMILES CC(C)CN1CCCC[C@H]1C(=O)Nc1cc(on1)C(C)(C)C
Show InChI InChI=1/C17H29N3O2/c1-12(2)11-20-9-7-6-8-13(20)16(21)18-15-10-14(22-19-15)17(3,4)5/h10,12-13H,6-9,11H2,1-5H3,(H,18,19,21)/t13-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.5n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042897
PNG
(CHEMBL3354531)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2CC2CC2)no1
Show InChI InChI=1/C17H27N3O2/c1-17(2,3)14-10-15(19-22-14)18-16(21)13-6-4-5-9-20(13)11-12-7-8-12/h10,12-13H,4-9,11H2,1-3H3,(H,18,19,21)/t13-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.900n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042898
PNG
(CHEMBL3354530)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C2CC2)no1
Show InChI InChI=1/C16H25N3O2/c1-16(2,3)13-10-14(18-21-13)17-15(20)12-6-4-5-9-19(12)11-7-8-11/h10-12H,4-9H2,1-3H3,(H,17,18,20)/t12-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 31n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...


Bioorg Med Chem Lett 25: 587-92 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042585
PNG
(CHEMBL3353864)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCCC2)no1
Show InChI InChI=1/C18H29N3O2/c1-18(2,3)15-12-16(20-23-15)19-17(22)14-10-7-11-21(14)13-8-5-4-6-9-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.200n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042585
PNG
(CHEMBL3353864)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCCC2)no1
Show InChI InChI=1/C18H29N3O2/c1-18(2,3)15-12-16(20-23-15)19-17(22)14-10-7-11-21(14)13-8-5-4-6-9-13/h12-14H,4-11H2,1-3H3,(H,19,20,22)/t14-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 390n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042599
PNG
(CHEMBL3353865)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCC2)no1
Show InChI InChI=1/C17H27N3O2/c1-17(2,3)14-11-15(19-22-14)18-16(21)13-9-6-10-20(13)12-7-4-5-8-12/h11-13H,4-10H2,1-3H3,(H,18,19,21)/t13-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.40E+3n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042648
PNG
(CHEMBL3353867)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CC2)no1
Show InChI InChI=1/C16H25N3O2/c1-16(2,3)13-9-14(18-21-13)17-15(20)12-5-4-8-19(12)10-11-6-7-11/h9,11-12H,4-8,10H2,1-3H3,(H,17,18,20)/t12-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 1.01E+4n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50042657
PNG
(CHEMBL3353868)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)no1
Show InChI InChI=1/C17H27N3O3/c1-17(2,3)14-11-15(19-23-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,19,21)/t13-/s2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.10E+4n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50042657
PNG
(CHEMBL3353868)
Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)no1
Show InChI InChI=1/C17H27N3O3/c1-17(2,3)14-11-15(19-23-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,19,21)/t13-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.40n/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins


Bioorg Med Chem Lett 25: 581-6 (2015)

More data for this
Ligand-Target Pair