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4 similar compounds to monomer 50040295

Compile data set for download or QSAR
Wt: 301.2
BDBM50453609
Wt: 271.2
BDBM50043339
Wt: 257.2
BDBM50043334
Wt: 257.2
BDBM50043336
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50453609,50043339,50043334,50043336   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MER intracellular domain/EGFR extracellular domain chimera


(Homo sapiens (Human))
BDBM50453609
PNG
(CHEMBL354521)
Show SMILES CCOC(=O)c1cc(ccc1O)\N=C\c1cc(O)ccc1O
Show InChI InChI=1S/C16H15NO5/c1-2-22-16(21)13-8-11(3-5-15(13)20)17-9-10-7-12(18)4-6-14(10)19/h3-9,18-20H,2H2,1H3/b17-9+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



U266 INSERM-URA D1500 CNRS

Curated by ChEMBL


Assay Description
Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membrane


J Med Chem 37: 845-59 (1994)


Article DOI: 10.1021/jm00032a020
BindingDB Entry DOI: 10.7270/Q2QV3KJ3
More data for this
Ligand-Target Pair
MER intracellular domain/EGFR extracellular domain chimera


(Homo sapiens (Human))
BDBM50453609
PNG
(CHEMBL354521)
Show SMILES CCOC(=O)c1cc(ccc1O)\N=C\c1cc(O)ccc1O
Show InChI InChI=1S/C16H15NO5/c1-2-22-16(21)13-8-11(3-5-15(13)20)17-9-10-7-12(18)4-6-14(10)19/h3-9,18-20H,2H2,1H3/b17-9+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



U266 INSERM-URA D1500 CNRS

Curated by ChEMBL


Assay Description
Inhibition of EGF-stimulated DNA synthesis in ER 22 (EGF-receptor expressing) cells


J Med Chem 37: 845-59 (1994)


Article DOI: 10.1021/jm00032a020
BindingDB Entry DOI: 10.7270/Q2QV3KJ3
More data for this
Ligand-Target Pair
MER intracellular domain/EGFR extracellular domain chimera


(Homo sapiens (Human))
BDBM50043336
PNG
(2-Hydroxy-5-[(2-hydroxy-benzylidene)-amino]-benzoi...)
Show SMILES OC(=O)c1cc(ccc1O)\N=C\c1ccccc1O
Show InChI InChI=1S/C14H11NO4/c16-12-4-2-1-3-9(12)8-15-10-5-6-13(17)11(7-10)14(18)19/h1-8,16-17H,(H,18,19)/b15-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdR


J Med Chem 36: 4094-8 (1994)


Article DOI: 10.1021/jm00077a014
BindingDB Entry DOI: 10.7270/Q2KS6QMV
More data for this
Ligand-Target Pair
MER intracellular domain/EGFR extracellular domain chimera


(Homo sapiens (Human))
BDBM50043334
PNG
(3-[(2,5-Dihydroxy-benzylidene)-amino]-benzoic acid...)
Show SMILES OC(=O)c1cccc(c1)\N=C\c1cc(O)ccc1O
Show InChI InChI=1S/C14H11NO4/c16-12-4-5-13(17)10(7-12)8-15-11-3-1-2-9(6-11)14(18)19/h1-8,16-17H,(H,18,19)/b15-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdR


J Med Chem 36: 4094-8 (1994)


Article DOI: 10.1021/jm00077a014
BindingDB Entry DOI: 10.7270/Q2KS6QMV
More data for this
Ligand-Target Pair
MER intracellular domain/EGFR extracellular domain chimera


(Homo sapiens (Human))
BDBM50043339
PNG
(2-Hydroxy-5-[(2-hydroxy-benzylidene)-amino]-benzoi...)
Show SMILES COC(=O)c1cc(ccc1O)\N=C\c1ccccc1O
Show InChI InChI=1S/C15H13NO4/c1-20-15(19)12-8-11(6-7-14(12)18)16-9-10-4-2-3-5-13(10)17/h2-9,17-18H,1H3/b16-9+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdR


J Med Chem 36: 4094-8 (1994)


Article DOI: 10.1021/jm00077a014
BindingDB Entry DOI: 10.7270/Q2KS6QMV
More data for this
Ligand-Target Pair