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2 similar compounds to monomer 50051349

Compile data set for download or QSAR
Wt: 244.1
BDBM50051341
Wt: 364.3
BDBM50293340

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051341,50293340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50051341
PNG
(4-Methoxy-5-oxo-5H-furo[3,2-g]chromene-7-carbaldeh...)
Show SMILES COc1c2ccoc2cc2oc(C=O)cc(=O)c12
Show InChI InChI=1S/C13H8O5/c1-16-13-8-2-3-17-10(8)5-11-12(13)9(15)4-7(6-14)18-11/h2-6H,1H3
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PC cid
PC sid
UniChem

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Similars

Article
PubMed
8.89E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Binding affinity against human adenosine A3 receptor in HEK293 cells using [125I]-AB-MECA 21680 radioligand.


J Med Chem 39: 2293-301 (1996)


Article DOI: 10.1021/jm950923i
BindingDB Entry DOI: 10.7270/Q2D799J2
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50051341
PNG
(4-Methoxy-5-oxo-5H-furo[3,2-g]chromene-7-carbaldeh...)
Show SMILES COc1c2ccoc2cc2oc(C=O)cc(=O)c12
Show InChI InChI=1S/C13H8O5/c1-16-13-8-2-3-17-10(8)5-11-12(13)9(15)4-7(6-14)18-11/h2-6H,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
8.91E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.


J Med Chem 41: 46-52 (1998)

Checked by Author
Article DOI: 10.1021/jm970446z
BindingDB Entry DOI: 10.7270/Q2NC62QT
More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50293340
PNG
(7-Methyl-4-(4-phenoxybutoxy)-5H-furo[3,2-g][1]benz...)
Show SMILES Cc1cc(=O)c2c(OCCCCOc3ccccc3)c3ccoc3cc2o1
Show InChI InChI=1S/C22H20O5/c1-15-13-18(23)21-20(27-15)14-19-17(9-12-25-19)22(21)26-11-6-5-10-24-16-7-3-2-4-8-16/h2-4,7-9,12-14H,5-6,10-11H2,1H3
PDB
MMDB

Reactome pathway
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UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 233n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of Kv1.3 potassium channel expressed in mouse L929 cells by whole cell patch clamp


Eur J Med Chem 44: 1838-52 (2009)


Article DOI: 10.1016/j.ejmech.2008.10.033
BindingDB Entry DOI: 10.7270/Q2QR4X5N
More data for this
Ligand-Target Pair