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17 similar compounds to monomer 50063231

Compile data set for download or QSAR
Wt: 437.6
BDBM50063234
Wt: 507.7
BDBM50063235
Wt: 465.6
BDBM50063236
Wt: 507.7
BDBM50063239
Wt: 367.4
BDBM50063241
Wt: 381.5
BDBM50063242
Wt: 577.8
BDBM50063245
Wt: 451.6
BDBM50063220
Wt: 535.8
BDBM50063221
Wt: 437.6
BDBM50063222
Wt: 591.9
BDBM50063223
Wt: 535.8
BDBM50063224
Wt: 549.8
BDBM50063225
Wt: 437.6
BDBM50063226
Wt: 479.6
BDBM50063229
Displayed 1 to 15 (of 17 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50063234,50063235,50063236,50063239,50063241,50063242,50063245,50063220,50063221,50063222,50063223,50063224,50063225,50063226,50063229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carboxylesterase 1


(Oryctolagus cuniculus (rabbit))
BDBM50063239
PNG
(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C33H49NO3/c1-6-7-8-9-10-11-12-13-14-18-24-37-33(36)30(27-20-16-15-17-21-27)32(35)34-31-28(25(2)3)22-19-23-29(31)26(4)5/h15-17,19-23,25-26,30H,6-14,18,24H2,1-5H3,(H,34,35)
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n/an/a 10n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal LAI assay


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063245
PNG
(CHEMBL159694 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCCCC(C)(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C38H59NO3/c1-8-9-10-11-12-13-14-15-16-17-18-22-28-38(6,7)42-37(41)34(31-24-20-19-21-25-31)36(40)39-35-32(29(2)3)26-23-27-33(35)30(4)5/h19-21,23-27,29-30,34H,8-18,22,28H2,1-7H3,(H,39,40)
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n/an/a 72n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063221
PNG
(CHEMBL161295 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C35H53NO3/c1-6-7-8-9-10-11-12-13-14-15-16-20-26-39-35(38)32(29-22-18-17-19-23-29)34(37)36-33-30(27(2)3)24-21-25-31(33)28(4)5/h17-19,21-25,27-28,32H,6-16,20,26H2,1-5H3,(H,36,37)
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n/an/a 16n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063222
PNG
(CHEMBL159993 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C28H39NO3/c1-6-7-8-9-13-19-32-28(31)25(22-15-11-10-12-16-22)27(30)29-26-23(20(2)3)17-14-18-24(26)21(4)5/h10-12,14-18,20-21,25H,6-9,13,19H2,1-5H3,(H,29,30)
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n/an/a 50n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063223
PNG
(CHEMBL159374 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C39H61NO3/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-24-30-43-39(42)36(33-26-22-21-23-27-33)38(41)40-37-34(31(2)3)28-25-29-35(37)32(4)5/h21-23,25-29,31-32,36H,6-20,24,30H2,1-5H3,(H,40,41)
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n/an/a 200n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063224
PNG
(CHEMBL159414 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCC(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C35H53NO3/c1-7-8-9-10-11-12-13-14-15-17-21-28(6)39-35(38)32(29-22-18-16-19-23-29)34(37)36-33-30(26(2)3)24-20-25-31(33)27(4)5/h16,18-20,22-28,32H,7-15,17,21H2,1-6H3,(H,36,37)
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n/an/a 22n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063226
PNG
(CHEMBL160149 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCC(C)(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C28H39NO3/c1-8-9-18-28(6,7)32-27(31)24(21-14-11-10-12-15-21)26(30)29-25-22(19(2)3)16-13-17-23(25)20(4)5/h10-17,19-20,24H,8-9,18H2,1-7H3,(H,29,30)
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n/an/a 11n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063225
PNG
(2-Phenyl-N-(2,4,6-triisopropyl-phenyl)-malonamic a...)
Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cc(cc1C(C)C)C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C36H55NO3/c1-8-9-10-11-12-13-14-15-16-20-23-40-36(39)33(29-21-18-17-19-22-29)35(38)37-34-31(27(4)5)24-30(26(2)3)25-32(34)28(6)7/h17-19,21-22,24-28,33H,8-16,20,23H2,1-7H3,(H,37,38)
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n/an/a 56n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063229
PNG
(CHEMBL161292 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C31H45NO3/c1-6-7-8-9-10-11-12-16-22-35-31(34)28(25-18-14-13-15-19-25)30(33)32-29-26(23(2)3)20-17-21-27(29)24(4)5/h13-15,17-21,23-24,28H,6-12,16,22H2,1-5H3,(H,32,33)
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n/an/a 13n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063234
PNG
(CHEMBL351398 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCC(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C28H39NO3/c1-7-8-10-14-21(6)32-28(31)25(22-15-11-9-12-16-22)27(30)29-26-23(19(2)3)17-13-18-24(26)20(4)5/h9,11-13,15-21,25H,7-8,10,14H2,1-6H3,(H,29,30)
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n/an/a 40n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063236
PNG
(CHEMBL159871 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C30H43NO3/c1-6-7-8-9-10-11-15-21-34-30(33)27(24-17-13-12-14-18-24)29(32)31-28-25(22(2)3)19-16-20-26(28)23(4)5/h12-14,16-20,22-23,27H,6-11,15,21H2,1-5H3,(H,31,32)
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n/an/a 12n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063235
PNG
(CHEMBL161798 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCC(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C33H49NO3/c1-7-8-9-10-11-12-13-15-19-26(6)37-33(36)30(27-20-16-14-17-21-27)32(35)34-31-28(24(2)3)22-18-23-29(31)25(4)5/h14,16-18,20-26,30H,7-13,15,19H2,1-6H3,(H,34,35)
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n/an/a 13n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063239
PNG
(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C33H49NO3/c1-6-7-8-9-10-11-12-13-14-18-24-37-33(36)30(27-20-16-15-17-21-27)32(35)34-31-28(25(2)3)22-19-23-29(31)26(4)5/h15-17,19-23,25-26,30H,6-14,18,24H2,1-5H3,(H,34,35)
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n/an/a 10n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063242
PNG
(CHEMBL350951 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C24H31NO3/c1-6-15-28-24(27)21(18-11-8-7-9-12-18)23(26)25-22-19(16(2)3)13-10-14-20(22)17(4)5/h7-14,16-17,21H,6,15H2,1-5H3,(H,25,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063241
PNG
(CHEMBL159680 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C23H29NO3/c1-6-27-23(26)20(17-11-8-7-9-12-17)22(25)24-21-18(15(2)3)13-10-14-19(21)16(4)5/h7-16,20H,6H2,1-5H3,(H,24,25)
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Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Carboxylesterase 1


(Oryctolagus cuniculus (rabbit))
BDBM50063239
PNG
(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C33H49NO3/c1-6-7-8-9-10-11-12-13-14-18-24-37-33(36)30(27-20-16-15-17-21-27)32(35)34-31-28(25(2)3)22-19-23-29(31)26(4)5/h15-17,19-23,25-26,30H,6-14,18,24H2,1-5H3,(H,34,35)
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n/an/a 20n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal MAI2 assay


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063220
PNG
(CHEMBL161270 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C29H41NO3/c1-6-7-8-9-10-14-20-33-29(32)26(23-16-12-11-13-17-23)28(31)30-27-24(21(2)3)18-15-19-25(27)22(4)5/h11-13,15-19,21-22,26H,6-10,14,20H2,1-5H3,(H,30,31)
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n/an/a 13n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair