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30 similar compounds to monomer 50077273

Compile data set for download or QSAR
Wt: 1808.1
BDBM50132596
Wt: 1166.4
BDBM50063809
Wt: 1192.4
BDBM50063815
Wt: 1218.4
BDBM50063817
Wt: 1192.4
BDBM50063838
Wt: 1113.3
BDBM50077266
Wt: 1102.2
BDBM50077278
Wt: 1257.2
BDBM50077281
Wt: 1257.2
BDBM50077286
Wt: 1102.2
BDBM50077295
Wt: 1246.2
BDBM50077304
Wt: 2092.3
BDBM50091858
Wt: 905.0
BDBM50132593
Wt: 1555.8
BDBM50134944
Wt: 1527.7
BDBM50134942
Displayed 1 to 15 (of 30 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 50132596,50063809,50063815,50063817,50063838,50077266,50077278,50077281,50077286,50077295,50077304,50091858,50132593,50134944,50134942   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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12n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077278
PNG
(CHEMBL407496 | H-Fpa-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(F)cc1
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-16-33(54)17-13-30)26-77-76-25-42(65-46(69)36(56)19-29-10-14-32(53)15-11-29)51(74)64-41(22-34-24-58-27-60-34)49(72)63-40(21-31-23-59-37-8-4-3-7-35(31)37)48(71)61-38(47(70)67-44)9-5-6-18-55/h3-4,7-8,10-17,23-24,27-28,36,38-44,59H,5-6,9,18-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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31n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077281
PNG
(CHEMBL438726 | H-Pfp-cyclo[DCys-D2Pal-DTrp-Lys-Val...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33+,34-,35+,46+/m0/s1
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34n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077295
PNG
(CHEMBL406491 | H-2Fpa-cyclo[DCys-His-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1F)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1F
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-4-7-15-35(30)54)26-77-76-25-42(65-46(69)36(56)19-29-11-3-6-14-34(29)53)51(74)64-41(22-32-24-58-27-60-32)49(72)63-40(21-31-23-59-37-16-8-5-13-33(31)37)48(71)61-38(47(70)67-44)17-9-10-18-55/h3-8,11-16,23-24,27-28,36,38-44,59H,9-10,17-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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37n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077304
PNG
(CHEMBL414598 | H-Pfp-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C52H57F10N13O8S2/c1-20(2)44-52(83)74-33(50(81)70-29(45(65)76)14-25-36(55)40(59)43(62)41(60)37(25)56)18-85-84-17-32(73-46(77)26(64)13-24-34(53)38(57)42(61)39(58)35(24)54)51(82)72-31(12-22-16-66-19-68-22)49(80)71-30(11-21-15-67-27-8-4-3-7-23(21)27)48(79)69-28(47(78)75-44)9-5-6-10-63/h3-4,7-8,15-16,19-20,26,28-33,44,67H,5-6,9-14,17-18,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t26-,28-,29-,30+,31-,32-,33-,44+/m0/s1
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69n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077266
PNG
(CHEMBL406152 | H-3Fpa-cyclo[DCys-Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(F)c1
Show InChI InChI=1S/C54H66F2N12O8S2/c1-30(2)46-54(76)67-45(52(74)63-41(47(59)69)23-32-11-8-14-36(56)21-32)29-78-77-28-44(66-48(70)38(58)22-31-10-7-13-35(55)20-31)53(75)64-42(24-33-12-9-19-60-26-33)50(72)65-43(25-34-27-61-39-16-4-3-15-37(34)39)51(73)62-40(49(71)68-46)17-5-6-18-57/h3-4,7-16,19-21,26-27,30,38,40-46,61H,5-6,17-18,22-25,28-29,57-58H2,1-2H3,(H2,59,69)(H,62,73)(H,63,74)(H,64,75)(H,65,72)(H,66,70)(H,67,76)(H,68,71)/t38-,40-,41-,42-,43+,44-,45+,46+/m0/s1
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82n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077281
PNG
(CHEMBL438726 | H-Pfp-cyclo[DCys-D2Pal-DTrp-Lys-Val...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33+,34-,35+,46+/m0/s1
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93n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077266
PNG
(CHEMBL406152 | H-3Fpa-cyclo[DCys-Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(F)c1
Show InChI InChI=1S/C54H66F2N12O8S2/c1-30(2)46-54(76)67-45(52(74)63-41(47(59)69)23-32-11-8-14-36(56)21-32)29-78-77-28-44(66-48(70)38(58)22-31-10-7-13-35(55)20-31)53(75)64-42(24-33-12-9-19-60-26-33)50(72)65-43(25-34-27-61-39-16-4-3-15-37(34)39)51(73)62-40(49(71)68-46)17-5-6-18-57/h3-4,7-16,19-21,26-27,30,38,40-46,61H,5-6,17-18,22-25,28-29,57-58H2,1-2H3,(H2,59,69)(H,62,73)(H,63,74)(H,64,75)(H,65,72)(H,66,70)(H,67,76)(H,68,71)/t38-,40-,41-,42-,43+,44-,45+,46+/m0/s1
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117n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077304
PNG
(CHEMBL414598 | H-Pfp-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C52H57F10N13O8S2/c1-20(2)44-52(83)74-33(50(81)70-29(45(65)76)14-25-36(55)40(59)43(62)41(60)37(25)56)18-85-84-17-32(73-46(77)26(64)13-24-34(53)38(57)42(61)39(58)35(24)54)51(82)72-31(12-22-16-66-19-68-22)49(80)71-30(11-21-15-67-27-8-4-3-7-23(21)27)48(79)69-28(47(78)75-44)9-5-6-10-63/h3-4,7-8,15-16,19-20,26,28-33,44,67H,5-6,9-14,17-18,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t26-,28-,29-,30+,31-,32-,33-,44+/m0/s1
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124n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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150n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077286
PNG
(CHEMBL437057 | H-Pfp-cyclo[DCys-2Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33-,34-,35+,46+/m0/s1
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170n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077278
PNG
(CHEMBL407496 | H-Fpa-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(F)cc1
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-16-33(54)17-13-30)26-77-76-25-42(65-46(69)36(56)19-29-10-14-32(53)15-11-29)51(74)64-41(22-34-24-58-27-60-34)49(72)63-40(21-31-23-59-37-8-4-3-7-35(31)37)48(71)61-38(47(70)67-44)9-5-6-18-55/h3-4,7-8,10-17,23-24,27-28,36,38-44,59H,5-6,9,18-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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173n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077295
PNG
(CHEMBL406491 | H-2Fpa-cyclo[DCys-His-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1F)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1F
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-4-7-15-35(30)54)26-77-76-25-42(65-46(69)36(56)19-29-11-3-6-14-34(29)53)51(74)64-41(22-32-24-58-27-60-32)49(72)63-40(21-31-23-59-37-16-8-5-13-33(31)37)48(71)61-38(47(70)67-44)17-9-10-18-55/h3-8,11-16,23-24,27-28,36,38-44,59H,9-10,17-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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176n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077278
PNG
(CHEMBL407496 | H-Fpa-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(F)cc1
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-16-33(54)17-13-30)26-77-76-25-42(65-46(69)36(56)19-29-10-14-32(53)15-11-29)51(74)64-41(22-34-24-58-27-60-34)49(72)63-40(21-31-23-59-37-8-4-3-7-35(31)37)48(71)61-38(47(70)67-44)9-5-6-18-55/h3-4,7-8,10-17,23-24,27-28,36,38-44,59H,5-6,9,18-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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269n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077295
PNG
(CHEMBL406491 | H-2Fpa-cyclo[DCys-His-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1F)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1F
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-4-7-15-35(30)54)26-77-76-25-42(65-46(69)36(56)19-29-11-3-6-14-34(29)53)51(74)64-41(22-32-24-58-27-60-32)49(72)63-40(21-31-23-59-37-16-8-5-13-33(31)37)48(71)61-38(47(70)67-44)17-9-10-18-55/h3-8,11-16,23-24,27-28,36,38-44,59H,9-10,17-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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382n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50077266
PNG
(CHEMBL406152 | H-3Fpa-cyclo[DCys-Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(F)c1
Show InChI InChI=1S/C54H66F2N12O8S2/c1-30(2)46-54(76)67-45(52(74)63-41(47(59)69)23-32-11-8-14-36(56)21-32)29-78-77-28-44(66-48(70)38(58)22-31-10-7-13-35(55)20-31)53(75)64-42(24-33-12-9-19-60-26-33)50(72)65-43(25-34-27-61-39-16-4-3-15-37(34)39)51(73)62-40(49(71)68-46)17-5-6-18-57/h3-4,7-16,19-21,26-27,30,38,40-46,61H,5-6,17-18,22-25,28-29,57-58H2,1-2H3,(H2,59,69)(H,62,73)(H,63,74)(H,64,75)(H,65,72)(H,66,70)(H,67,76)(H,68,71)/t38-,40-,41-,42-,43+,44-,45+,46+/m0/s1
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495n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 3


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077286
PNG
(CHEMBL437057 | H-Pfp-cyclo[DCys-2Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33-,34-,35+,46+/m0/s1
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568n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077304
PNG
(CHEMBL414598 | H-Pfp-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C52H57F10N13O8S2/c1-20(2)44-52(83)74-33(50(81)70-29(45(65)76)14-25-36(55)40(59)43(62)41(60)37(25)56)18-85-84-17-32(73-46(77)26(64)13-24-34(53)38(57)42(61)39(58)35(24)54)51(82)72-31(12-22-16-66-19-68-22)49(80)71-30(11-21-15-67-27-8-4-3-7-23(21)27)48(79)69-28(47(78)75-44)9-5-6-10-63/h3-4,7-8,15-16,19-20,26,28-33,44,67H,5-6,9-14,17-18,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t26-,28-,29-,30+,31-,32-,33-,44+/m0/s1
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637n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077281
PNG
(CHEMBL438726 | H-Pfp-cyclo[DCys-D2Pal-DTrp-Lys-Val...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33+,34-,35+,46+/m0/s1
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692n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077266
PNG
(CHEMBL406152 | H-3Fpa-cyclo[DCys-Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(F)c1
Show InChI InChI=1S/C54H66F2N12O8S2/c1-30(2)46-54(76)67-45(52(74)63-41(47(59)69)23-32-11-8-14-36(56)21-32)29-78-77-28-44(66-48(70)38(58)22-31-10-7-13-35(55)20-31)53(75)64-42(24-33-12-9-19-60-26-33)50(72)65-43(25-34-27-61-39-16-4-3-15-37(34)39)51(73)62-40(49(71)68-46)17-5-6-18-57/h3-4,7-16,19-21,26-27,30,38,40-46,61H,5-6,17-18,22-25,28-29,57-58H2,1-2H3,(H2,59,69)(H,62,73)(H,63,74)(H,64,75)(H,65,72)(H,66,70)(H,67,76)(H,68,71)/t38-,40-,41-,42-,43+,44-,45+,46+/m0/s1
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748n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM50077278
PNG
(CHEMBL407496 | H-Fpa-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(F)cc1
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-16-33(54)17-13-30)26-77-76-25-42(65-46(69)36(56)19-29-10-14-32(53)15-11-29)51(74)64-41(22-34-24-58-27-60-34)49(72)63-40(21-31-23-59-37-8-4-3-7-35(31)37)48(71)61-38(47(70)67-44)9-5-6-18-55/h3-4,7-8,10-17,23-24,27-28,36,38-44,59H,5-6,9,18-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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847n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 4


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077286
PNG
(CHEMBL437057 | H-Pfp-cyclo[DCys-2Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33-,34-,35+,46+/m0/s1
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918n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077304
PNG
(CHEMBL414598 | H-Pfp-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C52H57F10N13O8S2/c1-20(2)44-52(83)74-33(50(81)70-29(45(65)76)14-25-36(55)40(59)43(62)41(60)37(25)56)18-85-84-17-32(73-46(77)26(64)13-24-34(53)38(57)42(61)39(58)35(24)54)51(82)72-31(12-22-16-66-19-68-22)49(80)71-30(11-21-15-67-27-8-4-3-7-23(21)27)48(79)69-28(47(78)75-44)9-5-6-10-63/h3-4,7-8,15-16,19-20,26,28-33,44,67H,5-6,9-14,17-18,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t26-,28-,29-,30+,31-,32-,33-,44+/m0/s1
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926n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077295
PNG
(CHEMBL406491 | H-2Fpa-cyclo[DCys-His-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1F)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1F
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-4-7-15-35(30)54)26-77-76-25-42(65-46(69)36(56)19-29-11-3-6-14-34(29)53)51(74)64-41(22-32-24-58-27-60-32)49(72)63-40(21-31-23-59-37-16-8-5-13-33(31)37)48(71)61-38(47(70)67-44)17-9-10-18-55/h3-8,11-16,23-24,27-28,36,38-44,59H,9-10,17-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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972n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM50077295
PNG
(CHEMBL406491 | H-2Fpa-cyclo[DCys-His-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1F)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1F
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-4-7-15-35(30)54)26-77-76-25-42(65-46(69)36(56)19-29-11-3-6-14-34(29)53)51(74)64-41(22-32-24-58-27-60-32)49(72)63-40(21-31-23-59-37-16-8-5-13-33(31)37)48(71)61-38(47(70)67-44)17-9-10-18-55/h3-8,11-16,23-24,27-28,36,38-44,59H,9-10,17-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 4


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50077286
PNG
(CHEMBL437057 | H-Pfp-cyclo[DCys-2Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33-,34-,35+,46+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 2


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM50077266
PNG
(CHEMBL406152 | H-3Fpa-cyclo[DCys-Pal-DTrp-Lys-Val-...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(F)c1
Show InChI InChI=1S/C54H66F2N12O8S2/c1-30(2)46-54(76)67-45(52(74)63-41(47(59)69)23-32-11-8-14-36(56)21-32)29-78-77-28-44(66-48(70)38(58)22-31-10-7-13-35(55)20-31)53(75)64-42(24-33-12-9-19-60-26-33)50(72)65-43(25-34-27-61-39-16-4-3-15-37(34)39)51(73)62-40(49(71)68-46)17-5-6-18-57/h3-4,7-16,19-21,26-27,30,38,40-46,61H,5-6,17-18,22-25,28-29,57-58H2,1-2H3,(H2,59,69)(H,62,73)(H,63,74)(H,64,75)(H,65,72)(H,66,70)(H,67,76)(H,68,71)/t38-,40-,41-,42-,43+,44-,45+,46+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 4


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM50077304
PNG
(CHEMBL414598 | H-Pfp-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C52H57F10N13O8S2/c1-20(2)44-52(83)74-33(50(81)70-29(45(65)76)14-25-36(55)40(59)43(62)41(60)37(25)56)18-85-84-17-32(73-46(77)26(64)13-24-34(53)38(57)42(61)39(58)35(24)54)51(82)72-31(12-22-16-66-19-68-22)49(80)71-30(11-21-15-67-27-8-4-3-7-23(21)27)48(79)69-28(47(78)75-44)9-5-6-10-63/h3-4,7-8,15-16,19-20,26,28-33,44,67H,5-6,9-14,17-18,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t26-,28-,29-,30+,31-,32-,33-,44+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 4


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50077281
PNG
(CHEMBL438726 | H-Pfp-cyclo[DCys-D2Pal-DTrp-Lys-Val...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C54H58F10N12O8S2/c1-22(2)46-54(84)75-35(52(82)71-31(47(67)77)18-27-38(57)42(61)45(64)43(62)39(27)58)21-86-85-20-34(74-48(78)28(66)17-26-36(55)40(59)44(63)41(60)37(26)56)53(83)73-33(16-24-9-6-8-14-68-24)51(81)72-32(15-23-19-69-29-11-4-3-10-25(23)29)50(80)70-30(49(79)76-46)12-5-7-13-65/h3-4,6,8-11,14,19,22,28,30-35,46,69H,5,7,12-13,15-18,20-21,65-66H2,1-2H3,(H2,67,77)(H,70,80)(H,71,82)(H,72,81)(H,73,83)(H,74,78)(H,75,84)(H,76,79)/t28-,30-,31-,32+,33+,34-,35+,46+/m0/s1
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1.38E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 5


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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1.70E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50077278
PNG
(CHEMBL407496 | H-Fpa-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(F)cc1
Show InChI InChI=1S/C52H65F2N13O8S2/c1-28(2)44-52(75)66-43(50(73)62-39(45(57)68)20-30-12-16-33(54)17-13-30)26-77-76-25-42(65-46(69)36(56)19-29-10-14-32(53)15-11-29)51(74)64-41(22-34-24-58-27-60-34)49(72)63-40(21-31-23-59-37-8-4-3-7-35(31)37)48(71)61-38(47(70)67-44)9-5-6-18-55/h3-4,7-8,10-17,23-24,27-28,36,38-44,59H,5-6,9,18-22,25-26,55-56H2,1-2H3,(H2,57,68)(H,58,60)(H,61,71)(H,62,73)(H,63,72)(H,64,74)(H,65,69)(H,66,75)(H,67,70)/t36-,38-,39-,40+,41-,42-,43-,44+/m0/s1
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1.95E+3n/an/an/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against human Somatostatin receptor type 1


J Med Chem 42: 1863-71 (1999)


Article DOI: 10.1021/jm9806289
BindingDB Entry DOI: 10.7270/Q2XW4J03
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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>3.90E+3n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50132593
PNG
((S)-6-Amino-2-{(R)-2-[(S)-2-amino-3-(3H-imidazol-4...)
Show SMILES NCCCC[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C46H56N12O6S/c47-17-9-8-16-36(54-46(64)40(25-65)58-42(60)33(48)21-30-24-50-26-53-30)43(61)56-38(18-27-10-2-1-3-11-27)44(62)57-39(20-29-23-52-35-15-7-5-13-32(29)35)45(63)55-37(41(49)59)19-28-22-51-34-14-6-4-12-31(28)34/h1-7,10-15,22-24,26,33,36-40,51-52,65H,8-9,16-21,25,47-48H2,(H2,49,59)(H,50,53)(H,54,64)(H,55,63)(H,56,61)(H,57,62)(H,58,60)/t33-,36-,37-,38-,39-,40-/m0/s1
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n/an/a 1.02E+5n/an/an/an/an/an/a



NIH

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 integrase enzyme 3'-end processing


Bioorg Med Chem Lett 13: 3203-5 (2003)


Article DOI: 10.1016/s0960-894x(03)00679-6
BindingDB Entry DOI: 10.7270/Q23B5ZJN
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50132596
PNG
(CHEMBL2370434 | Dimeric peptide)
Show SMILES NCCCC[C@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C92H110N24O12S2/c93-33-17-15-31-71(85(121)111-75(35-53-19-3-1-4-20-53)87(123)113-77(39-57-45-103-69-29-13-9-25-63(57)69)89(125)109-73(81(97)117)37-55-43-101-67-27-11-7-23-61(55)67)107-91(127)79(115-83(119)65(95)41-59-47-99-51-105-59)49-129-130-50-80(116-84(120)66(96)42-60-48-100-52-106-60)92(128)108-72(32-16-18-34-94)86(122)112-76(36-54-21-5-2-6-22-54)88(124)114-78(40-58-46-104-70-30-14-10-26-64(58)70)90(126)110-74(82(98)118)38-56-44-102-68-28-12-8-24-62(56)68/h1-14,19-30,43-48,51-52,65-66,71-80,101-104H,15-18,31-42,49-50,93-96H2,(H2,97,117)(H2,98,118)(H,99,105)(H,100,106)(H,107,127)(H,108,128)(H,109,125)(H,110,126)(H,111,121)(H,112,122)(H,113,123)(H,114,124)(H,115,119)(H,116,120)/t65-,66-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-/m0/s1
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n/an/a 5.80E+4n/an/an/an/an/an/a



NIH

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 integrase enzyme strand transfer process


Bioorg Med Chem Lett 13: 3203-5 (2003)


Article DOI: 10.1016/s0960-894x(03)00679-6
BindingDB Entry DOI: 10.7270/Q23B5ZJN
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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n/an/an/an/a 400n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50134942
PNG
(CHEMBL411564 | H-Tyr-Val-c[Cys-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C71H94N22O13S2/c1-39(2)59(93-60(97)47(72)27-42-21-23-45(94)24-22-42)69(106)92-55-36-107-108-37-56(68(105)87-50(20-12-26-80-71(76)77)63(100)88-51(61(98)82-34-57(73)95)28-40-13-5-3-6-14-40)91-66(103)53(30-43-32-81-48-18-10-9-17-46(43)48)90-64(101)49(19-11-25-79-70(74)75)86-65(102)52(29-41-15-7-4-8-16-41)89-67(104)54(31-44-33-78-38-84-44)85-58(96)35-83-62(55)99/h3-10,13-18,21-24,32-33,38-39,47,49-56,59,81,94H,11-12,19-20,25-31,34-37,72H2,1-2H3,(H2,73,95)(H,78,84)(H,82,98)(H,83,99)(H,85,96)(H,86,102)(H,87,105)(H,88,100)(H,89,104)(H,90,101)(H,91,103)(H,92,106)(H,93,97)(H4,74,75,79)(H4,76,77,80)/t47-,49-,50-,51-,52+,53-,54-,55+,56+,59-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Erythropoietin receptor


(Homo sapiens (Human))
BDBM50091858
PNG
(CHEMBL440818 | GGQPK-cyclic-(CVWTLPGFHC)-YSTGG-NH2)
Show SMILES CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)CN)C(C)C)[C@@H](C)O
Show InChI InChI=1S/C94H134N26O25S2/c1-48(2)32-65-94(145)119-30-14-21-69(119)88(139)103-43-76(130)107-61(33-52-16-8-7-9-17-52)81(132)110-64(36-55-39-99-47-105-55)83(134)115-67(86(137)109-62(34-53-23-25-56(124)26-24-53)82(133)113-66(44-121)85(136)117-78(50(5)122)90(141)104-41-74(128)101-40-72(98)126)45-146-147-46-68(87(138)116-77(49(3)4)91(142)111-63(84(135)118-79(51(6)123)92(143)112-65)35-54-38-100-58-19-11-10-18-57(54)58)114-80(131)59(20-12-13-29-95)108-89(140)70-22-15-31-120(70)93(144)60(27-28-71(97)125)106-75(129)42-102-73(127)37-96/h7-11,16-19,23-26,38-39,47-51,59-70,77-79,100,121-124H,12-15,20-22,27-37,40-46,95-96H2,1-6H3,(H2,97,125)(H2,98,126)(H,99,105)(H,101,128)(H,102,127)(H,103,139)(H,104,141)(H,106,129)(H,107,130)(H,108,140)(H,109,137)(H,110,132)(H,111,142)(H,112,143)(H,113,133)(H,114,131)(H,115,134)(H,116,138)(H,117,136)(H,118,135)/t50-,51-,59+,60+,61+,62+,63+,64+,65+,66+,67+,68-,69+,70+,77+,78+,79+/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibition of [125I]-EPO binding to Erythropoietin receptor (EBP)


Bioorg Med Chem Lett 10: 1995-9 (2001)


Article DOI: 10.1016/s0960-894x(00)00399-1
BindingDB Entry DOI: 10.7270/Q2TH8KXD
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50134944
PNG
(CHEMBL409049 | H-Tyr-Val-c[Pen-Gly-His-Phe-Arg-Trp...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C73H98N22O13S2/c1-40(2)59(94-61(99)48(74)29-43-23-25-46(96)26-24-43)69(107)95-60-70(108)85-37-58(98)87-55(33-45-35-80-39-86-45)67(105)91-53(31-42-17-9-6-10-18-42)65(103)88-50(21-13-27-81-71(76)77)64(102)92-54(32-44-34-83-49-20-12-11-19-47(44)49)66(104)93-56(38-109-110-73(60,3)4)68(106)89-51(22-14-28-82-72(78)79)63(101)90-52(62(100)84-36-57(75)97)30-41-15-7-5-8-16-41/h5-12,15-20,23-26,34-35,39-40,48,50-56,59-60,83,96H,13-14,21-22,27-33,36-38,74H2,1-4H3,(H2,75,97)(H,80,86)(H,84,100)(H,85,108)(H,87,98)(H,88,103)(H,89,106)(H,90,101)(H,91,105)(H,92,102)(H,93,104)(H,94,99)(H,95,107)(H4,76,77,81)(H4,78,79,82)/t48-,50-,51-,52-,53+,54-,55-,56-,59-,60-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay.


J Med Chem 46: 4965-73 (2003)


Article DOI: 10.1021/jm030119t
BindingDB Entry DOI: 10.7270/Q2SJ1K0P
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50063809
PNG
(CHEMBL437081 | H-Nal-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1
Show InChI InChI=1S/C60H71N13O8S2/c1-34(2)52-60(81)72-51(58(79)68-47(53(63)74)26-36-19-21-38-12-4-6-14-40(38)24-36)32-83-82-31-50(71-54(75)44(62)25-35-18-20-37-11-3-5-13-39(37)23-35)59(80)70-49(28-42-30-64-33-66-42)57(78)69-48(27-41-29-65-45-16-8-7-15-43(41)45)56(77)67-46(55(76)73-52)17-9-10-22-61/h3-8,11-16,18-21,23-24,29-30,33-34,44,46-52,65H,9-10,17,22,25-28,31-32,61-62H2,1-2H3,(H2,63,74)(H,64,66)(H,67,77)(H,68,79)(H,69,78)(H,70,80)(H,71,75)(H,72,81)(H,73,76)/t44-,46+,47-,48-,49+,50+,51-,52-/m0/s1
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n/an/a 68n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 3 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50063815
PNG
(CHEMBL440067 | H-Nal-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1
Show InChI InChI=1S/C62H73N13O8S2/c1-36(2)54-62(83)74-53(60(81)70-49(55(65)76)28-37-13-12-18-42(25-37)39-14-4-3-5-15-39)34-85-84-33-52(73-56(77)46(64)27-38-22-23-40-16-6-7-17-41(40)26-38)61(82)72-51(30-44-32-66-35-68-44)59(80)71-50(29-43-31-67-47-20-9-8-19-45(43)47)58(79)69-48(57(78)75-54)21-10-11-24-63/h3-9,12-20,22-23,25-26,31-32,35-36,46,48-54,67H,10-11,21,24,27-30,33-34,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t46-,48+,49-,50-,51+,52+,53-,54-/m0/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 5 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50063817
PNG
(CHEMBL429371 | H-Dip-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C64H75N13O8S2/c1-38(2)56-64(85)76-55(62(83)72-51(57(67)78)30-40-16-14-22-44(28-40)42-19-7-4-8-20-42)36-87-86-35-54(75-58(79)48(66)29-39-15-13-21-43(27-39)41-17-5-3-6-18-41)63(84)74-53(32-46-34-68-37-70-46)61(82)73-52(31-45-33-69-49-24-10-9-23-47(45)49)60(81)71-50(59(80)77-56)25-11-12-26-65/h3-10,13-24,27-28,33-34,37-38,48,50-56,69H,11-12,25-26,29-32,35-36,65-66H2,1-2H3,(H2,67,78)(H,68,70)(H,71,81)(H,72,83)(H,73,82)(H,74,84)(H,75,79)(H,76,85)(H,77,80)/t48-,50+,51-,52-,53+,54+,55-,56-/m0/s1
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n/an/a 669n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 2 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50063809
PNG
(CHEMBL437081 | H-Nal-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1
Show InChI InChI=1S/C60H71N13O8S2/c1-34(2)52-60(81)72-51(58(79)68-47(53(63)74)26-36-19-21-38-12-4-6-14-40(38)24-36)32-83-82-31-50(71-54(75)44(62)25-35-18-20-37-11-3-5-13-39(37)23-35)59(80)70-49(28-42-30-64-33-66-42)57(78)69-48(27-41-29-65-45-16-8-7-15-43(41)45)56(77)67-46(55(76)73-52)17-9-10-22-61/h3-8,11-16,18-21,23-24,29-30,33-34,44,46-52,65H,9-10,17,22,25-28,31-32,61-62H2,1-2H3,(H2,63,74)(H,64,66)(H,67,77)(H,68,79)(H,69,78)(H,70,80)(H,71,75)(H,72,81)(H,73,76)/t44-,46+,47-,48-,49+,50+,51-,52-/m0/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 1 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50063838
PNG
(CHEMBL217216 | H-Dip-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C62H73N13O8S2/c1-36(2)54-62(83)74-53(60(81)70-49(55(65)76)28-38-22-23-40-16-6-7-17-41(40)26-38)34-85-84-33-52(73-56(77)46(64)27-37-13-12-18-42(25-37)39-14-4-3-5-15-39)61(82)72-51(30-44-32-66-35-68-44)59(80)71-50(29-43-31-67-47-20-9-8-19-45(43)47)58(79)69-48(57(78)75-54)21-10-11-24-63/h3-9,12-20,22-23,25-26,31-32,35-36,46,48-54,67H,10-11,21,24,27-30,33-34,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t46-,48+,49-,50-,51+,52+,53-,54-/m0/s1
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n/an/a 1.01E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 1 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50063815
PNG
(CHEMBL440067 | H-Nal-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1
Show InChI InChI=1S/C62H73N13O8S2/c1-36(2)54-62(83)74-53(60(81)70-49(55(65)76)28-37-13-12-18-42(25-37)39-14-4-3-5-15-39)34-85-84-33-52(73-56(77)46(64)27-38-22-23-40-16-6-7-17-41(40)26-38)61(82)72-51(30-44-32-66-35-68-44)59(80)71-50(29-43-31-67-47-20-9-8-19-45(43)47)58(79)69-48(57(78)75-54)21-10-11-24-63/h3-9,12-20,22-23,25-26,31-32,35-36,46,48-54,67H,10-11,21,24,27-30,33-34,63-64H2,1-2H3,(H2,65,76)(H,66,68)(H,69,79)(H,70,81)(H,71,80)(H,72,82)(H,73,77)(H,74,83)(H,75,78)/t46-,48+,49-,50-,51+,52+,53-,54-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 3 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50063817
PNG
(CHEMBL429371 | H-Dip-cyclo[DCys-His-DTrp-Lys-Val-C...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C64H75N13O8S2/c1-38(2)56-64(85)76-55(62(83)72-51(57(67)78)30-40-16-14-22-44(28-40)42-19-7-4-8-20-42)36-87-86-35-54(75-58(79)48(66)29-39-15-13-21-43(27-39)41-17-5-3-6-18-41)63(84)74-53(32-46-34-68-37-70-46)61(82)73-52(31-45-33-69-49-24-10-9-23-47(45)49)60(81)71-50(59(80)77-56)25-11-12-26-65/h3-10,13-24,27-28,33-34,37-38,48,50-56,69H,11-12,25-26,29-32,35-36,65-66H2,1-2H3,(H2,67,78)(H,68,70)(H,71,81)(H,72,83)(H,73,82)(H,74,84)(H,75,79)(H,76,85)(H,77,80)/t48-,50+,51-,52-,53+,54+,55-,56-/m0/s1
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n/an/a 1.48E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human somatostatin 5 (hsst) receptor


J Med Chem 41: 1146-54 (1998)


Article DOI: 10.1021/jm970730q
BindingDB Entry DOI: 10.7270/Q26W9BS9
More data for this
Ligand-Target Pair
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