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1 similar compounds to monomer 50062136

Compile data set for download or QSAR
Wt: 188.2
BDBM50066777

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066777   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.12E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.29E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.39E+5n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50066777
PNG
(5-Benzyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hy...)
Show SMILES CC1CC(N)=NC1Cc1ccccc1
Show InChI InChI=1/C12H16N2/c1-9-7-12(13)14-11(9)8-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,13,14)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.39E+5n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)


J Med Chem 41: 3675-83 (1998)


Article DOI: 10.1021/jm970840x
BindingDB Entry DOI: 10.7270/Q2XP75MP
More data for this
Ligand-Target Pair