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1 similar compounds to monomer 50310818

Compile data set for download or QSAR
Wt: 320.4
BDBM50066843

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066843   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epoxide hydrolase 2


(Rattus norvegicus)
BDBM50066843
PNG
(CHEMBL3401636)
Show SMILES O=C(N[C@H]1[C@@H]([C@@H]1c1ccccc1)c1ccccc1)N1CCCCC1
Show InChI InChI=1/C21H24N2O/c24-21(23-14-8-3-9-15-23)22-20-18(16-10-4-1-5-11-16)19(20)17-12-6-2-7-13-17/h1-2,4-7,10-13,18-20H,3,8-9,14-15H2,(H,22,24)/t18-,19+,20+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate reader


Bioorg Med Chem Lett 25: 1705-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.02.076
BindingDB Entry DOI: 10.7270/Q25H7HX9
More data for this
Ligand-Target Pair
Epoxide hydratase


(Homo sapiens (Human))
BDBM50066843
PNG
(CHEMBL3401636)
Show SMILES O=C(N[C@H]1[C@@H]([C@@H]1c1ccccc1)c1ccccc1)N1CCCCC1
Show InChI InChI=1/C21H24N2O/c24-21(23-14-8-3-9-15-23)22-20-18(16-10-4-1-5-11-16)19(20)17-12-6-2-7-13-17/h1-2,4-7,10-13,18-20H,3,8-9,14-15H2,(H,22,24)/t18-,19+,20+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant human soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate reader


Bioorg Med Chem Lett 25: 1705-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.02.076
BindingDB Entry DOI: 10.7270/Q25H7HX9
More data for this
Ligand-Target Pair