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56 similar compounds to monomer 50124595

Compile data set for download or QSAR
Wt: 367.4
BDBM50067679
Wt: 363.4
BDBM50072699
Wt: 325.8
BDBM50072701
Wt: 367.9
BDBM50072704
Wt: 317.4
BDBM50072707
Wt: 363.4
BDBM50107344
Wt: 378.5
BDBM50107345
Wt: 349.4
BDBM50107346
Wt: 347.4
BDBM50107347
Wt: 351.4
BDBM50107351
Wt: 397.5
BDBM50107354
Wt: 335.4
BDBM50107355
Wt: 349.4
BDBM50107364
Wt: 446.7
BDBM50124591
Wt: 375.4
BDBM50124592
Displayed 1 to 15 (of 56 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 79 hits for monomerid = 50067679,50072699,50072701,50072704,50072707,50107344,50107345,50107346,50107347,50107351,50107354,50107355,50107364,50124591,50124592   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50072701
PNG
(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Show SMILES CC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C20H20ClNO/c1-11-10-20(3,4)22-16-7-6-14-15-9-13(21)5-8-17(15)23-12(2)19(14)18(11)16/h5-10,12,22H,1-4H3
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0.440n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assay


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072701
PNG
(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Show SMILES CC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C20H20ClNO/c1-11-10-20(3,4)22-16-7-6-14-15-9-13(21)5-8-17(15)23-12(2)19(14)18(11)16/h5-10,12,22H,1-4H3
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0.440n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptor


J Med Chem 42: 1466-72 (1999)


Article DOI: 10.1021/jm980723h
BindingDB Entry DOI: 10.7270/Q2NK3FQ9
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072704
PNG
(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Show SMILES CCCCC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H26ClNO/c1-5-6-7-20-22-16(17-12-15(24)8-11-19(17)26-20)9-10-18-21(22)14(2)13-23(3,4)25-18/h8-13,20,25H,5-7H2,1-4H3
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0.870n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assay


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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1.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067679
PNG
(5-Benzyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(Cc4ccccc4)c3c12
Show InChI InChI=1S/C26H25NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-14,16,23,27H,15H2,1-3H3
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2.10n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124591
PNG
(5-Allyl-7-bromo-10-chloro-2,2,4-trimethyl-2,5-dihy...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4c(Br)cc(O)c(Cl)c-34)c12
Show InChI InChI=1S/C22H21BrClNO2/c1-5-6-16-18-12(19-20(24)15(26)9-13(23)21(19)27-16)7-8-14-17(18)11(2)10-22(3,4)25-14/h5,7-10,16,25-26H,1,6H2,2-4H3
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2.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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2.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072699
PNG
(5-Butyl-9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CCCCC1Oc2ccc(OC)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C24H29NO2/c1-6-7-8-21-23-17(18-13-16(26-5)9-12-20(18)27-21)10-11-19-22(23)15(2)14-24(3,4)25-19/h9-14,21,25H,6-8H2,1-5H3
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3.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assay


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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4.80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assay


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107346
PNG
(10-Methoxy-2,2,4-trimethyl-5-propyl-2,5-dihydro-1H...)
Show SMILES CCCC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H27NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h7,9-13,18,24H,6,8H2,1-5H3
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5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107354
PNG
(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1cccc2OC(Cc3ccccc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C27H27NO2/c1-17-16-27(2,3)28-20-14-13-19-25-21(29-4)11-8-12-22(25)30-23(26(19)24(17)20)15-18-9-6-5-7-10-18/h5-14,16,23,28H,15H2,1-4H3
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8.10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107364
PNG
(5-Isopropyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro...)
Show SMILES COc1cccc2OC(C(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H27NO2/c1-13(2)22-21-15(20-17(25-6)8-7-9-18(20)26-22)10-11-16-19(21)14(3)12-23(4,5)24-16/h7-13,22,24H,1-6H3
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9n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107344
PNG
(5-Isobutyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H29NO2/c1-14(2)12-20-23-16(22-18(26-6)8-7-9-19(22)27-20)10-11-17-21(23)15(3)13-24(4,5)25-17/h7-11,13-14,20,25H,12H2,1-6H3
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9.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107355
PNG
(5-Ethyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CCC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C22H25NO2/c1-6-16-21-14(20-17(24-5)8-7-9-18(20)25-16)10-11-15-19(21)13(2)12-22(3,4)23-15/h7-12,16,23H,6H2,1-5H3
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14n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124591
PNG
(5-Allyl-7-bromo-10-chloro-2,2,4-trimethyl-2,5-dihy...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4c(Br)cc(O)c(Cl)c-34)c12
Show InChI InChI=1S/C22H21BrClNO2/c1-5-6-16-18-12(19-20(24)15(26)9-13(23)21(19)27-16)7-8-14-17(18)11(2)10-22(3,4)25-14/h5,7-10,16,25-26H,1,6H2,2-4H3
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22n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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36n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107345
PNG
(CHEMBL141426 | [2-(10-Methoxy-2,2,4-trimethyl-2,5-...)
Show SMILES COc1cccc2OC(CCN(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H30N2O2/c1-15-14-24(2,3)25-17-11-10-16-22-18(27-6)8-7-9-19(22)28-20(12-13-26(4)5)23(16)21(15)17/h7-11,14,20,25H,12-13H2,1-6H3
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62n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107351
PNG
(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Show SMILES COc1cccc2OC(CCO)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C22H25NO3/c1-13-12-22(2,3)23-15-9-8-14-20-16(25-4)6-5-7-17(20)26-18(10-11-24)21(14)19(13)15/h5-9,12,18,23-24H,10-11H2,1-4H3
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106n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072699
PNG
(5-Butyl-9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CCCCC1Oc2ccc(OC)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C24H29NO2/c1-6-7-8-21-23-17(18-13-16(26-5)9-12-20(18)27-21)10-11-19-22(23)15(2)14-24(3,4)25-19/h9-14,21,25H,6-8H2,1-5H3
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130n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of Dexamethasone from human glucocorticoid receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072701
PNG
(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Show SMILES CC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C20H20ClNO/c1-11-10-20(3,4)22-16-7-6-14-15-9-13(21)5-8-17(15)23-12(2)19(14)18(11)16/h5-10,12,22H,1-4H3
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367n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of Dexamethasone from human glucocorticoid receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072704
PNG
(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Show SMILES CCCCC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H26ClNO/c1-5-6-7-20-22-16(17-12-15(24)8-11-19(17)26-20)9-10-18-21(22)14(2)13-23(3,4)25-18/h8-13,20,25H,5-7H2,1-4H3
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394n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of Dexamethasone from human glucocorticoid receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124592
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES COC(=O)c1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H25NO3/c1-6-8-18-22-15(11-12-17-20(22)14(2)13-24(3,4)25-17)21-16(23(26)27-5)9-7-10-19(21)28-18/h6-7,9-13,18,25H,1,8H2,2-5H3
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400n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50072701
PNG
(9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-...)
Show SMILES CC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C20H20ClNO/c1-11-10-20(3,4)22-16-7-6-14-15-9-13(21)5-8-17(15)23-12(2)19(14)18(11)16/h5-10,12,22H,1-4H3
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621n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of DHT from human androgen receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50072699
PNG
(5-Butyl-9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CCCCC1Oc2ccc(OC)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C24H29NO2/c1-6-7-8-21-23-17(18-13-16(26-5)9-12-20(18)27-21)10-11-19-22(23)15(2)14-24(3,4)25-19/h9-14,21,25H,6-8H2,1-5H3
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785n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of DHT from human androgen receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50072704
PNG
(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Show SMILES CCCCC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H26ClNO/c1-5-6-7-20-22-16(17-12-15(24)8-11-19(17)26-20)9-10-18-21(22)14(2)13-23(3,4)25-18/h8-13,20,25H,5-7H2,1-4H3
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886n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of DHT from human androgen receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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889n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of Dexamethasone from human glucocorticoid receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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>1.00E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of DHT from human androgen receptor


Bioorg Med Chem Lett 8: 3365-70 (1999)


Article DOI: 10.1016/s0960-894x(98)00608-8
BindingDB Entry DOI: 10.7270/Q2BC402X
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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1.23E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards testosterone receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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1.79E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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1.80E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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1.80E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107354
PNG
(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1cccc2OC(Cc3ccccc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C27H27NO2/c1-17-16-27(2,3)28-20-14-13-19-25-21(29-4)11-8-12-22(25)30-23(26(19)24(17)20)15-18-9-6-5-7-10-18/h5-14,16,23,28H,15H2,1-4H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107344
PNG
(5-Isobutyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H29NO2/c1-14(2)12-20-23-16(22-18(26-6)8-7-9-19(22)27-20)10-11-17-21(23)15(3)13-24(4,5)25-17/h7-11,13-14,20,25H,12H2,1-6H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107351
PNG
(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Show SMILES COc1cccc2OC(CCO)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C22H25NO3/c1-13-12-22(2,3)23-15-9-8-14-20-16(25-4)6-5-7-17(20)26-18(10-11-24)21(14)19(13)15/h5-9,12,18,23-24H,10-11H2,1-4H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107355
PNG
(5-Ethyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CCC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C22H25NO2/c1-6-16-21-14(20-17(24-5)8-7-9-18(20)25-16)10-11-15-19(21)13(2)12-22(3,4)23-15/h7-12,16,23H,6H2,1-5H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards testosterone receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107346
PNG
(10-Methoxy-2,2,4-trimethyl-5-propyl-2,5-dihydro-1H...)
Show SMILES CCCC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H27NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h7,9-13,18,24H,6,8H2,1-5H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107364
PNG
(5-Isopropyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro...)
Show SMILES COc1cccc2OC(C(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H27NO2/c1-13(2)22-21-15(20-17(25-6)8-7-9-18(20)26-22)10-11-16-19(21)14(3)12-23(4,5)24-16/h7-13,22,24H,1-6H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50107345
PNG
(CHEMBL141426 | [2-(10-Methoxy-2,2,4-trimethyl-2,5-...)
Show SMILES COc1cccc2OC(CCN(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H30N2O2/c1-15-14-24(2,3)25-17-11-10-16-22-18(27-6)8-7-9-19(22)28-20(12-13-26(4)5)23(16)21(15)17/h7-11,14,20,25H,12-13H2,1-6H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards progesterone receptor (PR) by displacing [3H]-progesterone.


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/a 13n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transcriptional repression in CV-1 cells expressing glucocorticoid receptor


Bioorg Med Chem Lett 14: 1721-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.044
BindingDB Entry DOI: 10.7270/Q2KP81M9
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transcriptional repression in CV-1 cells expressing glucocorticoid receptor


Bioorg Med Chem Lett 14: 1721-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.044
BindingDB Entry DOI: 10.7270/Q2KP81M9
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/a 33n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transcriptional activation in CV-1 cells expressing glucocorticoid receptor


Bioorg Med Chem Lett 14: 1721-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.044
BindingDB Entry DOI: 10.7270/Q2KP81M9
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/a 6.90n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transcriptional repression in CV-1 cells expressing glucocorticoid receptor


Bioorg Med Chem Lett 14: 1721-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.044
BindingDB Entry DOI: 10.7270/Q2KP81M9
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107354
PNG
(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1cccc2OC(Cc3ccccc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C27H27NO2/c1-17-16-27(2,3)28-20-14-13-19-25-21(29-4)11-8-12-22(25)30-23(26(19)24(17)20)15-18-9-6-5-7-10-18/h5-14,16,23,28H,15H2,1-4H3
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n/an/an/an/a 255n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107346
PNG
(10-Methoxy-2,2,4-trimethyl-5-propyl-2,5-dihydro-1H...)
Show SMILES CCCC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
Show InChI InChI=1S/C23H27NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h7,9-13,18,24H,6,8H2,1-5H3
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n/an/an/an/a 70n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107364
PNG
(5-Isopropyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro...)
Show SMILES COc1cccc2OC(C(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H27NO2/c1-13(2)22-21-15(20-17(25-6)8-7-9-18(20)26-22)10-11-16-19(21)14(3)12-23(4,5)24-16/h7-13,22,24H,1-6H3
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n/an/an/an/a 39n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/an/an/a 13n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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n/an/an/an/a 33n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107344
PNG
(5-Isobutyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC(C)C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
Show InChI InChI=1S/C24H29NO2/c1-14(2)12-20-23-16(22-18(26-6)8-7-9-19(22)27-20)10-11-17-21(23)15(3)13-24(4,5)25-17/h7-11,13-14,20,25H,12H2,1-6H3
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n/an/an/an/a 223n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).


J Med Chem 44: 4481-91 (2001)


Article DOI: 10.1021/jm010367u
BindingDB Entry DOI: 10.7270/Q2CZ36F4
More data for this
Ligand-Target Pair
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