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2 similar compounds to monomer 50070076

Wt: 302.8
BDBM50070119
Wt: 270.7
BDBM50070116

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070119,50070116   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50070119
PNG
(CHEMBL3408022)
Show SMILES N=C(Nc1ccccc1)Nc1ccc2CCCCc2n1
Show InChI InChI=1S/C16H18N4/c17-16(18-13-7-2-1-3-8-13)20-15-11-10-12-6-4-5-9-14(12)19-15/h1-3,7-8,10-11H,4-6,9H2,(H3,17,18,19,20)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
178n/an/an/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of [3H]-RX-821002 from human alpha-2 adrenergic receptor in brain prefrontal cortex membrane by liquid scintillation spectrometry


J Med Chem 58: 963-77 (2015)

More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50070116
PNG
(CHEMBL3408025)
Show SMILES CCONC(=N)Nc1ccc2CCCCc2n1
Show InChI InChI=1S/C12H18N4O/c1-2-17-16-12(13)15-11-8-7-9-5-3-4-6-10(9)14-11/h7-8H,2-6H2,1H3,(H3,13,14,15,16)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.48E+3n/an/an/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of [3H]-RX-821002 from human alpha-2 adrenergic receptor in brain prefrontal cortex membrane by liquid scintillation spectrometry


J Med Chem 58: 963-77 (2015)

More data for this
Ligand-Target Pair