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35 similar compounds to monomer 50092567

Compile data set for download or QSAR
Wt: 546.6
BDBM50073718
Wt: 580.6
BDBM50073719
Wt: 680.8
BDBM50073720
Wt: 580.6
BDBM50073721
Wt: 680.8
BDBM50073722
Wt: 546.6
BDBM50073723
Wt: 680.8
BDBM50073724
Wt: 580.6
BDBM50073725
Wt: 580.6
BDBM50073726
Wt: 680.8
BDBM50073728
Wt: 580.6
BDBM50092575
Wt: 565.6
BDBM50092576
Wt: 580.6
BDBM50092577
Wt: 566.6
BDBM50092578
Wt: 594.6
BDBM50092565
Displayed 1 to 15 (of 35 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50073718,50073719,50073720,50073721,50073722,50073723,50073724,50073725,50073726,50073728,50092575,50092576,50092577,50092578,50092565   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(MOUSE)
BDBM50073718
PNG
((S)-3-[((2S,5S,11bR)-2-tert-Butoxycarbonylamino-3-...)
Show SMILES CC(C)(C)OC(=O)N[C@H]1C[C@H]2N([C@@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@H](CC(O)=O)Cc2ccccc2)C1=O
Show InChI InChI=1S/C30H34N4O6/c1-30(2,3)40-29(39)33-22-16-23-26-20(19-11-7-8-12-21(19)32-26)15-24(34(23)28(22)38)27(37)31-18(14-25(35)36)13-17-9-5-4-6-10-17/h4-12,18,22-24,32H,13-16H2,1-3H3,(H,31,37)(H,33,39)(H,35,36)/t18-,22-,23+,24-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092577
PNG
((2S,5S,11bR,1'R)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c1-42-32(40)26(16-20-10-4-2-5-11-20)35-30(38)28-17-23-22-14-8-9-15-24(22)34-29(23)27-18-25(31(39)37(27)28)36-33(41)43-19-21-12-6-3-7-13-21/h2-15,25-28,34H,16-19H2,1H3,(H,35,38)(H,36,41)/t25-,26+,27+,28-/m0/s1
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Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073720
PNG
((S)-3-[((2S,5S,11bR)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31-,32+,33-/m0/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073719
PNG
((S)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27-,28-/m0/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073721
PNG
((2S,5S,11bR,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27-,28+/m1/s1
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n/an/a 2.70E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073722
PNG
((S)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31-,32-,33-/m0/s1
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n/an/a 460n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073723
PNG
((R)-3-[((2S,5S,11bR)-2-tert-Butoxycarbonylamino-3-...)
Show SMILES CC(C)(C)OC(=O)N[C@H]1C[C@H]2N([C@@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@@H](CC(O)=O)Cc2ccccc2)C1=O
Show InChI InChI=1S/C30H34N4O6/c1-30(2,3)40-29(39)33-22-16-23-26-20(19-11-7-8-12-21(19)32-26)15-24(34(23)28(22)38)27(37)31-18(14-25(35)36)13-17-9-5-4-6-10-17/h4-12,18,22-24,32H,13-16H2,1-3H3,(H,31,37)(H,33,39)(H,35,36)/t18-,22+,23-,24+/m1/s1
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n/an/a 4.48E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073724
PNG
((R)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31+,32+,33+/m1/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073721
PNG
((2S,5S,11bR,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27-,28+/m1/s1
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n/an/a 7.40n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073723
PNG
((R)-3-[((2S,5S,11bR)-2-tert-Butoxycarbonylamino-3-...)
Show SMILES CC(C)(C)OC(=O)N[C@H]1C[C@H]2N([C@@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@@H](CC(O)=O)Cc2ccccc2)C1=O
Show InChI InChI=1S/C30H34N4O6/c1-30(2,3)40-29(39)33-22-16-23-26-20(19-11-7-8-12-21(19)32-26)15-24(34(23)28(22)38)27(37)31-18(14-25(35)36)13-17-9-5-4-6-10-17/h4-12,18,22-24,32H,13-16H2,1-3H3,(H,31,37)(H,33,39)(H,35,36)/t18-,22+,23-,24+/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073718
PNG
((S)-3-[((2S,5S,11bR)-2-tert-Butoxycarbonylamino-3-...)
Show SMILES CC(C)(C)OC(=O)N[C@H]1C[C@H]2N([C@@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@H](CC(O)=O)Cc2ccccc2)C1=O
Show InChI InChI=1S/C30H34N4O6/c1-30(2,3)40-29(39)33-22-16-23-26-20(19-11-7-8-12-21(19)32-26)15-24(34(23)28(22)38)27(37)31-18(14-25(35)36)13-17-9-5-4-6-10-17/h4-12,18,22-24,32H,13-16H2,1-3H3,(H,31,37)(H,33,39)(H,35,36)/t18-,22-,23+,24-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073725
PNG
((2S,5S,11bR,1'S)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27+,28-/m0/s1
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n/an/a 88n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073720
PNG
((S)-3-[((2S,5S,11bR)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31-,32+,33-/m0/s1
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n/an/a 220n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073726
PNG
((R)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27+,28+/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073724
PNG
((R)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31+,32+,33+/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073728
PNG
((R)-3-[((2S,5S,11bR)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31+,32-,33+/m1/s1
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n/an/a 180n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073726
PNG
((R)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27+,28+/m1/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073725
PNG
((2S,5S,11bR,1'S)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27+,28-/m0/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073722
PNG
((S)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31-,32-,33-/m0/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50073728
PNG
((R)-3-[((2S,5S,11bR)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES C[Si](C)(C)CCOC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C38H44N4O6Si/c1-49(2,3)19-18-47-34(43)21-27(20-25-12-6-4-7-13-25)39-36(44)33-22-29-28-16-10-11-17-30(28)40-35(29)32-23-31(37(45)42(32)33)41-38(46)48-24-26-14-8-5-9-15-26/h4-17,27,31-33,40H,18-24H2,1-3H3,(H,39,44)(H,41,46)/t27-,31+,32-,33+/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 specific binding to rat cerebral cortex membranes Cholecystokinin type B receptor


Bioorg Med Chem Lett 12: 109-12 (2001)


Article DOI: 10.1016/s0960-894x(01)00630-8
BindingDB Entry DOI: 10.7270/Q2P84B5G
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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n/an/a 4.70n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 specific binding to rat pancreatic Cholecystokinin type A receptor


Bioorg Med Chem Lett 12: 109-12 (2001)


Article DOI: 10.1016/s0960-894x(01)00630-8
BindingDB Entry DOI: 10.7270/Q2P84B5G
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Displacement of [3H]propionylCCK8 from rat cerebral cortex CCK2


J Med Chem 48: 7667-74 (2005)


Article DOI: 10.1021/jm050689o
BindingDB Entry DOI: 10.7270/Q2QJ7GV9
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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n/an/a 4.70n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Displacement of [3H]propionylCCK8 from rat pancreatic CCK1


J Med Chem 48: 7667-74 (2005)


Article DOI: 10.1021/jm050689o
BindingDB Entry DOI: 10.7270/Q2QJ7GV9
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092565
PNG
((2R,5R,11bS,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C34H34N4O6/c1-43-30(39)17-23(16-21-10-4-2-5-11-21)35-32(40)29-18-25-24-14-8-9-15-26(24)36-31(25)28-19-27(33(41)38(28)29)37-34(42)44-20-22-12-6-3-7-13-22/h2-15,23,27-29,36H,16-20H2,1H3,(H,35,40)(H,37,42)/t23-,27-,28+,29-/m1/s1
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n/an/a 4.91E+3n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50073725
PNG
((2S,5S,11bR,1'S)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27+,28-/m0/s1
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Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092575
PNG
((2R,5R,11bS,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c1-42-32(40)26(16-20-10-4-2-5-11-20)35-30(38)28-17-23-22-14-8-9-15-24(22)34-29(23)27-18-25(31(39)37(27)28)36-33(41)43-19-21-12-6-3-7-13-21/h2-15,25-28,34H,16-19H2,1H3,(H,35,38)(H,36,41)/t25-,26+,27+,28-/m1/s1
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Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092576
PNG
((2S,5S,11bR,1'R)-[5-(1-Carbamoyl-2-phenyl-ethylcar...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H31N5O5/c33-29(38)24(15-19-9-3-1-4-10-19)35-30(39)27-16-22-21-13-7-8-14-23(21)34-28(22)26-17-25(31(40)37(26)27)36-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,34H,15-18H2,(H2,33,38)(H,35,39)(H,36,41)/t24-,25+,26-,27+/m1/s1
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Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50073721
PNG
((2S,5S,11bR,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27-,28+/m1/s1
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n/an/a 2.70E+3n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092576
PNG
((2S,5S,11bR,1'R)-[5-(1-Carbamoyl-2-phenyl-ethylcar...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H31N5O5/c33-29(38)24(15-19-9-3-1-4-10-19)35-30(39)27-16-22-21-13-7-8-14-23(21)34-28(22)26-17-25(31(40)37(26)27)36-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,34H,15-18H2,(H2,33,38)(H,35,39)(H,36,41)/t24-,25+,26-,27+/m1/s1
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Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092577
PNG
((2S,5S,11bR,1'R)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c1-42-32(40)26(16-20-10-4-2-5-11-20)35-30(38)28-17-23-22-14-8-9-15-24(22)34-29(23)27-18-25(31(39)37(27)28)36-33(41)43-19-21-12-6-3-7-13-21/h2-15,25-28,34H,16-19H2,1H3,(H,35,38)(H,36,41)/t25-,26+,27+,28-/m0/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073721
PNG
((2S,5S,11bR,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26+,27-,28+/m1/s1
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n/an/a 7.40n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50092575
PNG
((2R,5R,11bS,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c1-42-32(40)26(16-20-10-4-2-5-11-20)35-30(38)28-17-23-22-14-8-9-15-24(22)34-29(23)27-18-25(31(39)37(27)28)36-33(41)43-19-21-12-6-3-7-13-21/h2-15,25-28,34H,16-19H2,1H3,(H,35,38)(H,36,41)/t25-,26+,27+,28-/m1/s1
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n/an/a 5.63E+3n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat cerebral cortex membranes at Cholecystokinin type B receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092578
PNG
((2S,5S,11bR,1'S)-2-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C32H30N4O6/c37-29(34-25(31(39)40)15-19-9-3-1-4-10-19)27-16-22-21-13-7-8-14-23(21)33-28(22)26-17-24(30(38)36(26)27)35-32(41)42-18-20-11-5-2-6-12-20/h1-14,24-27,33H,15-18H2,(H,34,37)(H,35,41)(H,39,40)/t24-,25-,26+,27-/m0/s1
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n/an/a 4.70n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50092565
PNG
((2R,5R,11bS,1'R)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES COC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C34H34N4O6/c1-43-30(39)17-23(16-21-10-4-2-5-11-21)35-32(40)29-18-25-24-14-8-9-15-26(24)36-31(25)28-19-27(33(41)38(28)29)37-34(42)44-20-22-12-6-3-7-13-22/h2-15,23,27-29,36H,16-20H2,1H3,(H,35,40)(H,37,42)/t23-,27-,28+,29-/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073725
PNG
((2S,5S,11bR,1'S)-3-[(2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27+,28-/m0/s1
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n/an/a 88n/an/an/an/an/an/a



Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]propionyl-CCK-8 binding to rat pancreatic membranes at Cholecystokinin type A receptor.


J Med Chem 43: 3770-7 (2000)


Article DOI: 10.1021/jm000959x
BindingDB Entry DOI: 10.7270/Q21J9BG8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50073719
PNG
((S)-3-[((2S,5S,11bS)-2-Benzyloxycarbonylamino-3-ox...)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Show InChI InChI=1S/C33H32N4O6/c38-29(39)16-22(15-20-9-3-1-4-10-20)34-31(40)28-17-24-23-13-7-8-14-25(23)35-30(24)27-18-26(32(41)37(27)28)36-33(42)43-19-21-11-5-2-6-12-21/h1-14,22,26-28,35H,15-19H2,(H,34,40)(H,36,42)(H,38,39)/t22-,26-,27-,28-/m0/s1
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n/an/a 635n/an/an/an/an/an/a



Instituto de Química Médica (CSIC)

Curated by ChEMBL


Assay Description
Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptor


Bioorg Med Chem Lett 9: 43-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00677-5
BindingDB Entry DOI: 10.7270/Q2XP743J
More data for this
Ligand-Target Pair